PRESS-RELEASE ·Filed Mar 18, 2026

SPRO

Spero Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonimmediate Processed6mo ago WireGlobeNewswire
Press release: earnings
Actionable Insight • Neutral

Traders should prepare for a potentially muted reaction post-release due to lack of a conference call; monitor the earnings press release closely for any surprises in financials or pipeline updates.

DirectionNeutral
Confidencemedium
Horizonimmediate
Final — all horizons settled through T+60d
SPRO ▲ +17.81% at T+60d
NEUTRAL call ✓ call won +17.81% · α vs SPY +3.47% · entry $2.47 → $2.91
Entry anchored
Mar 18, 03:59 PM ET
via exchange tick
T+1d
-4.05%
call -4.05% · α -2.31%
$2.37
settled 7mo ago
T+5d
-4.05%
call -4.05% · α -1.84%
$2.37
settled 6mo ago
T+20d
+11.34%
call +11.34% · α +3.71%
$2.75
settled 6mo ago
T+60d
+17.81%
call +17.81% · α +3.47%
$2.91
settled 4mo ago

Price Chart

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Executive Summary

Spero Therapeutics announced it will release its Q4 and full-year 2025 financial results on March 26, 2026, after market close. The company will not host a conference call, limiting immediate investor engagement and real-time clarification of results.

Key Facts

  • Spero Therapeutics will report Q4 and full-year 2025 financial results on March 26, 2026, after market close.
  • No conference call is planned, which may limit investor interaction and near-term market reaction.
  • Company remains focused on clinical-stage development for rare and high unmet need diseases.

Financial Impact

Results pending — no financial figures provided in this release

revenueepscashFlow

Risk Factors

  • Lack of management commentary via conference call increases risk of misinterpretation or delayed reaction to results.
  • As a clinical-stage biopharma with no commercial revenue, financial results will likely reflect continued R&D spend and cash burn.

Market Snapshot

Exchange
Nasdaq

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3258588
13 reports for SPRO
Performance horizon
63% Hit rate 5 of 8 directional calls best @ T+20▲ +14.59%Mar 26, 2026
Filters
Rows
Reports for SPRO — sortable, filterable
TypeNow
Sep 11, 2026
21d ago
EFFECT
BEARISH ★ 7/10
$1.13 $1.13· 0.00%▼ −0.34%$1.19 (−5.31%)
Aug 28, 2026
4w ago
8-K
BEARISH ★ 7/10
$1.22 $1.19▲ +2.46%▲ +2.32%$1.19 (+2.46%)
Aug 28, 2026
4w ago
S-3
BEARISH ★ 7/10
$1.22 $1.19▲ +2.46%▲ +2.32%$1.19 (+2.46%)
Aug 12, 2026
7w ago
Press Release
NEUTRAL ★ 4/10
$1.24 $1.22▼ −1.61%▲ +0.35%$1.19 (−4.03%)
Jul 14, 2026
11w ago
8-K
BULLISH ★ 8/10
$1.70 $1.44▼ −15.29%▼ −14.00%$1.19 (−30.00%)
Jul 14, 2026
11w ago
Press Release
BULLISH ★ 7/10
$1.70 $1.44▼ −15.29%▼ −14.00%$1.19 (−30.00%)
Jun 25, 2026
14w ago
8-K
NEUTRAL ★ 3/10
$2.26 $2.20▼ −2.65%▼ −4.82%$1.19 (−47.35%)
Jun 22, 2026
14w ago
8-K
BULLISH ★ 8/10
$2.15 $2.26▲ +5.12%▲ +4.10%$1.19 (−44.65%)
Jun 17, 2026
15w ago
Press Release
BULLISH ★ 8/10
$2.11 $2.10▼ −0.47%▲ +0.57%$1.19 (−43.60%)
May 13, 2026
20w ago
8-K
MIXED ★ 5/10
$2.76 $2.69▼ −2.54%▼ −1.82%$1.19 (−56.88%)
Showing 10 of 13

US Market Status

Market Closed — Opens Mon (65h)

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Report published Mar 18, 2026