PRESS-RELEASE ·Filed Aug 12, 2026

SPRO

Spero Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonmonths Processed1mo ago WireGlobeNewswire
Press release: earnings
Actionable Insight • Neutral

As a clinical-stage biotech with no revenue, the key catalysts are pipeline milestones and regulatory updates. Monitor for upcoming data readouts or partnership announcements, as these are the primary drivers for the stock. The current cash position provides a runway into 2027, reducing near-term financing risk.

DirectionNeutral
Confidencemedium
Horizonmonths
Latest settled — T+20d
SPRO ▼ -8.87% at T+20d
NEUTRAL call ✗ call lost -8.87% · α vs SPY -7.12% · entry $1.24 → $1.13
Next anchor: T+60d in 5w
Latest observation: T+34 +65.72% FF3 residual α
Entry anchored
Aug 12, 04:00 PM ET
via 1-min bar
T+1d
-0.81%
call -0.81% · α -0.61%
$1.23
settled 7w ago
T+5d
-1.61%
call -1.61% · α +0.35%
$1.22
settled 6w ago
T+20d
-8.87%
call -8.87% · α -7.12%
$1.13
settled 22d ago
T+60d
—
call — · α —
—
in 5w

Price Chart

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Executive Summary

Spero Therapeutics reported Q2 2026 financial results, highlighting a net loss of $11.0 million for the quarter, compared to a net loss of $10.7 million in the same period last year. The company ended the quarter with $60.7 million in cash, cash equivalents, and marketable securities, providing a runway into 2027. The results are largely neutral for a clinical-stage biotech with no approved products, as the focus remains on pipeline development rather than financial performance.

Key Financial Metrics

EPS
$-0.13
Revenue
$0.00
est $0.00
Rating
in line

Key Facts

  • Net loss of $11.0 million for Q2 2026, compared to $10.7 million in Q2 2025.
  • Cash, cash equivalents, and marketable securities of $60.7 million as of June 30, 2026.
  • Research and development expenses were $7.5 million for Q2 2026, down from $8.5 million in Q2 2025.
  • General and administrative expenses were $4.2 million for Q2 2026, compared to $4.0 million in Q2 2025.
  • No revenue was reported for the quarter, consistent with the company's clinical-stage status.

Financial Impact

Net loss of $11.0 million, with cash runway into 2027.

net losscash positionr&d expenses

Risk Factors

  • Clinical trial failures or delays could significantly impact the stock.
  • Need for future capital raises to fund operations beyond current cash runway.
  • No approved products or revenue streams, making the company entirely dependent on pipeline success.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
0% bullish (6 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3344036
13 reports for SPRO
Performance horizon
63% Hit rate 5 of 8 directional calls best @ T+20▲ +14.59%Mar 26, 2026
Filters
Rows
Reports for SPRO — sortable, filterable
TypeNow
Sep 11, 2026
21d ago
EFFECT
BEARISH ★ 7/10
$1.13 $1.13· 0.00%▼ −0.34%$1.20 (−5.75%)
Aug 28, 2026
4w ago
8-K
BEARISH ★ 7/10
$1.22 $1.19▲ +2.46%▲ +2.32%$1.20 (+2.05%)
Aug 28, 2026
4w ago
S-3
BEARISH ★ 7/10
$1.22 $1.19▲ +2.46%▲ +2.32%$1.20 (+2.05%)
Aug 12, 2026
7w ago
Press Release
NEUTRAL ★ 4/10
$1.24 $1.22▼ −1.61%▲ +0.35%$1.20 (−3.63%)
Jul 14, 2026
11w ago
8-K
BULLISH ★ 8/10
$1.70 $1.44▼ −15.29%▼ −14.00%$1.20 (−29.71%)
Jul 14, 2026
11w ago
Press Release
BULLISH ★ 7/10
$1.70 $1.44▼ −15.29%▼ −14.00%$1.20 (−29.71%)
Jun 25, 2026
14w ago
8-K
NEUTRAL ★ 3/10
$2.26 $2.20▼ −2.65%▼ −4.82%$1.20 (−47.12%)
Jun 22, 2026
14w ago
8-K
BULLISH ★ 8/10
$2.15 $2.26▲ +5.12%▲ +4.10%$1.20 (−44.42%)
Jun 17, 2026
15w ago
Press Release
BULLISH ★ 8/10
$2.11 $2.10▼ −0.47%▲ +0.57%$1.20 (−43.36%)
May 13, 2026
20w ago
8-K
MIXED ★ 5/10
$2.76 $2.69▼ −2.54%▼ −1.82%$1.20 (−56.70%)
Showing 10 of 13

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Report published Aug 12, 2026