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S-3ASR ·Filed Jun 26, 2026

SYRE

Spyre Therapeutics, Inc.
NEUTRAL
Impact 5/10
Horizondays Processed3mo ago SEC0001628280-26-045742
Notable filing: S-3ASR
Actionable Insight • Neutral

LLM returned non-JSON response. Review the filing manually.

DirectionNeutral
Confidencelow
Horizondays
Final — all horizons settled through T+60d ⚠ clustered
SYRE ▲ +2.01% at T+60d
NEUTRAL call ✓ call won +2.01% · α vs SPY -2.38% · entry $90.16 → $91.97
Entry anchored
Jun 26, 03:59 PM ET
via exchange tick
T+1d
-1.53%
call -1.53% · α -2.31%
$88.78
settled 3mo ago
T+5d
-1.57%
call -1.57% · α -2.96%
$88.74
settled 3mo ago
T+20d
+13.28%
call +13.28% · α +13.56%
$102.13
settled 2mo ago
T+60d
+2.01%
call +2.01% · α -2.38%
$91.97
settled 10d ago

Price Chart

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Executive Summary

{ "summary": "Spyre Therapeutics filed an automatic shelf registration statement (S-3ASR) on June 26, 2026, registering an unlimited amount of securities, and concurrently entered into a $500M at-the-market (ATM) sales agreement with TD Cowen for common stock. The company has a $7.8B market cap, a strong cash position from prior raises, and no disclosed need for immediate capital, making this an opportunistic shelf filing to maintain financial flexibility rather than a distress-driven raise.",

Financial Impact

Unknown

Risk Factors

  • Analysis may be incomplete

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
96% bullish (23 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 8 SEC documents filed with EDGAR.

DocumentAccession Number
S-3ASR Filing (Primary)0001628280-26-045742
Exhibit: exhibit12-sx3asr.htm0001628280-26-045742
Exhibit: exfilingfees-s3asr.htm0001628280-26-045742
Exhibit: exhibit51-sx3asr.htm0001628280-26-045742
Exhibit: exhibit52-sx3asr.htm0001628280-26-045742
Exhibit: exhibit232-sx3asr.htm0001628280-26-045742
Exhibit: exhibit231-sx3asr.htm0001628280-26-045742
Document: spyre-formsx3asrjune2026.htm0001628280-26-045742
26 reports for SYRE
Performance horizon
77% Hit rate 10 of 13 directional calls best @ T+60▲ +54.27%Apr 13, 2026
Filters
Rows
Reports for SYRE — sortable, filterable
TypeNow
Sep 4, 2026
28d ago
Insider Cluster
BEARISH ★ 5/10
$88.98 $90.80▼ −2.05%▼ −3.25%$93.19 (−4.73%)
Aug 11, 2026
7w ago
Insider Cluster
BEARISH ★ 5/10
$102.74 $107.82▼ −4.94%▼ −5.35%$93.19 (+9.30%)
Aug 6, 2026
8w ago
Insider Cluster
BEARISH ★ 5/10
$103.42 $101.85▲ +1.52%▲ +2.73%$93.19 (+9.89%)
Jul 3, 2026
13w ago
Insider Cluster
NEUTRAL ★ 3/10
$86.63 $98.75▲ +13.99%▲ +13.06%$93.19 (+7.57%)
Jun 27, 2026
13w ago
Insider Cluster
BEARISH ★ 7/10
$90.16 $88.74▲ +1.57%▲ +2.96%$93.19 (−3.36%)
Jun 26, 2026
14w ago
S-3ASR
NEUTRAL ★ 5/10
$90.16 $88.74▼ −1.57%▼ −2.96%$93.19 (+3.36%)
Jun 24, 2026
14w ago
Insider Cluster
BEARISH ★ 7/10
$86.24 $88.89▼ −3.07%▼ −1.37%$93.19 (−8.06%)
Jun 15, 2026
15w ago
8-K
BULLISH ★ 7/10
$83.58 $100.32▲ +20.03%▲ +21.41%$93.19 (+11.50%)
Jun 12, 2026
16w ago
Institutional Cluster
BULLISH ★ 6/10
$80.79 $88.34▲ +9.35%▲ +8.67%$93.19 (+15.35%)
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 3/10
$80.77 $87.49▲ +8.32%▲ +7.89%$93.19 (+15.38%)
Showing 10 of 26

US Market Status

Market Closed — Opens Mon (65h 4m)

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