This cluster is routine — the dollar value is negligible relative to Spyre's $6.9B market cap. The CMO's derivative exercise is a standard cashless exercise, not a signal. No action warranted. Monitor for any material change in insider selling velocity (e.g., >$10M in a 7-day window) before assigning directional significance.
Price Chart
Executive Summary
CEO and CMO sold a combined $1.85M in open-market sales at ~$69.50, representing 0.027% of Spyre's $6.9B market cap. The CMO also exercised and sold shares from a derivative grant, a routine cashless exercise pattern. The dollar amount is trivial relative to market cap, making this a routine cluster with no material directional signal.
Key Financial Metrics
Key Facts
- CEO Turtle Cameron sold 5,300 shares for $369K on May 1, 2026
- CMO Sloan Sheldon sold 21,306 shares for $1.48M on May 1, 2026
- CMO also exercised 78,333 derivative shares at $27.46 ($2.15M) and 78,333 at $0 (non-cash award) — these are non-cash events
- Total open-market sales of $1.85M represent just 0.027% of $6.9B market cap
- No open-market purchases in the cluster
Financial Impact
Total insider sales of $1.85M, or 0.027% of market cap — immaterial
Risk Factors
- Insider selling could accelerate ahead of a catalyst event (e.g., clinical data readout)
- CEO selling, while small, is the first CEO sale in the recent 30-day window — worth tracking
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 1 SEC document filed with EDGAR.
| Document | Accession Number |
|---|---|
| CLUSTER Data (Synthetic) | cluster-SYRE-1777685708871 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Sep 4, 2026 28d ago | Insider Cluster | $88.98 $90.80 | ▼ −2.05% | ▼ −3.25% | $93.19 (−4.73%) |
Aug 11, 2026 7w ago | Insider Cluster | $102.74 $107.82 | ▼ −4.94% | ▼ −5.35% | $93.19 (+9.30%) |
Aug 6, 2026 8w ago | Insider Cluster | $103.42 $101.85 | ▲ +1.52% | ▲ +2.73% | $93.19 (+9.89%) |
Jul 3, 2026 13w ago | Insider Cluster | $86.63 $98.75 | ▲ +13.99% | ▲ +13.06% | $93.19 (+7.57%) |
Jun 27, 2026 13w ago | Insider Cluster | $90.16 $88.74 | ▲ +1.57% | ▲ +2.96% | $93.19 (−3.36%) |
Jun 26, 2026 14w ago | S-3ASR | $90.16 $88.74 | ▼ −1.57% | ▼ −2.96% | $93.19 (+3.36%) |
Jun 24, 2026 14w ago | Insider Cluster | $86.24 $88.89 | ▼ −3.07% | ▼ −1.37% | $93.19 (−8.06%) |
Jun 15, 2026 15w ago | 8-K | $83.58 $100.32 | ▲ +20.03% | ▲ +21.41% | $93.19 (+11.50%) |
Jun 12, 2026 16w ago | Institutional Cluster | $80.79 $88.34 | ▲ +9.35% | ▲ +8.67% | $93.19 (+15.35%) |
Jun 11, 2026 16w ago | Institutional Cluster | $80.77 $87.49 | ▲ +8.32% | ▲ +7.89% | $93.19 (+15.38%) |
US Market Status
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