While the dollar amount is not large relative to market cap, the coordinated exit by two top executives immediately after exercising options may signal lack of near-term conviction. Traders should monitor for absence of offsetting buys and watch for upcoming earnings or clinical updates that could explain timing.
Price Chart
Executive Summary
Two key executives at Spyre Therapeutics — the CFO and CMO — sold a combined $703K in open-market transactions on April 1, 2026, following derivative exercises. The sales represent a modest but notable insider selling cluster involving C-suite leadership.
Key Financial Metrics
Key Facts
- CFO Burrows Scott L sold 6,200 shares for $305,102 at $49.21 per share.
- CMO Sloan Sheldon sold 7,958 shares for $397,900 at $50.00 per share.
- Both executives also exercised in-the-money derivatives prior to selling, with no additional open-market purchases.
- Total open-market sale value: $703K, representing ~0.019% of $3.7B market cap — modest in size but significant due to C-suite participation.
- No insider buying was reported in the cluster.
Financial Impact
$703,000 in net insider selling by CFO and CMO
Risk Factors
- Perception of insider pessimism given no reinvestment or retention of shares post-exercise.
- Potential for negative market reaction due to C-suite selling, especially if no clear rationale is disclosed.
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 1 SEC document filed with EDGAR.
| Document | Accession Number |
|---|---|
| CLUSTER Data (Synthetic) | cluster-SYRE-1775266236001 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Sep 4, 2026 28d ago | Insider Cluster | $88.98 $90.80 | ▼ −2.05% | ▼ −3.25% | $93.19 (−4.73%) |
Aug 11, 2026 7w ago | Insider Cluster | $102.74 $107.82 | ▼ −4.94% | ▼ −5.35% | $93.19 (+9.30%) |
Aug 6, 2026 8w ago | Insider Cluster | $103.42 $101.85 | ▲ +1.52% | ▲ +2.73% | $93.19 (+9.89%) |
Jul 3, 2026 13w ago | Insider Cluster | $86.63 $98.75 | ▲ +13.99% | ▲ +13.06% | $93.19 (+7.57%) |
Jun 27, 2026 13w ago | Insider Cluster | $90.16 $88.74 | ▲ +1.57% | ▲ +2.96% | $93.19 (−3.36%) |
Jun 26, 2026 14w ago | S-3ASR | $90.16 $88.74 | ▼ −1.57% | ▼ −2.96% | $93.19 (+3.36%) |
Jun 24, 2026 14w ago | Insider Cluster | $86.24 $88.89 | ▼ −3.07% | ▼ −1.37% | $93.19 (−8.06%) |
Jun 15, 2026 15w ago | 8-K | $83.58 $100.32 | ▲ +20.03% | ▲ +21.41% | $93.19 (+11.50%) |
Jun 12, 2026 16w ago | Institutional Cluster | $80.79 $88.34 | ▲ +9.35% | ▲ +8.67% | $93.19 (+15.35%) |
Jun 11, 2026 16w ago | Institutional Cluster | $80.77 $87.49 | ▲ +8.32% | ▲ +7.89% | $93.19 (+15.38%) |
US Market Status
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