Insider Cluster (2 insiders) ·Filed Apr 16, 2026

SION

Sionna Therapeutics, Inc.
BEARISH
Impact 6/10
Horizondays Processed5mo ago
Insider cluster: 2 insiders, $12.6M total
Actionable Insight ▼ Bearish

This level of coordinated insider selling by two directors, especially a single transaction exceeding $10 million, signals meaningful lack of confidence at the board level. Traders should watch for downward pressure on the stock and monitor upcoming filings for further dispositions or commentary on financial health.

DirectionBearish
Confidencehigh
Horizondays
Final — all horizons settled through T+60d
SION ▼ -2.85% at T+60d
SHORT call ✓ call won +2.85% · α vs SPY +9.90% · entry $45.24 → $43.95
Entry anchored
Apr 15, 03:59 PM ET
via exchange tick
T+1d
-3.76%
call +3.76% · α +4.97%
$43.54
settled 6mo ago
T+5d
-15.23%
call +15.23% · α +16.21%
$38.35
settled 5mo ago
T+20d
-4.69%
call +4.69% · α +10.50%
$43.12
settled 5mo ago
T+60d
-2.85%
call +2.85% · α +9.90%
$43.95
settled 3mo ago

Price Chart

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Executive Summary

Two company insiders, both directors, sold shares in a concentrated 7-day window, totaling $12.63 million in open-market transactions. The largest sale came from Thompson Peter A., who disposed of 226,906 shares for $10.29 million, followed by Orbimed Advisors LLC selling $2.34 million worth. This represents a significant insider selling cluster just below 0.7% of the company's $1.9B market cap.

Key Financial Metrics

Direction
selling
Total Value
$12.6M
Insiders
2

Key Facts

  • Two directors executed open-market sales totaling $12.63 million over four days in mid-April 2026.
  • Thompson Peter A. sold 226,906 shares at $45.34, generating $10.29 million in proceeds.
  • Orbimed Advisors LLC sold 52,397 shares at $44.68, totaling $2.34 million.
  • Total cluster value represents approximately 0.66% of Sionna Therapeutics' $1.9B market capitalization.
  • All transactions were open-market sales (S code), indicating direct liquidity events, not tax-related or derivative settlements.

Financial Impact

$12.63 million in insider sales over 7 days

insider ownershipmarket sentimentshare supply

Risk Factors

  • Sustained insider selling could erode investor confidence and drive share price lower.
  • Large open-market transactions may indicate anticipation of negative news or limited near-term catalysts.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-SION-1776818445260
16 reports for SION
Performance horizon
83% Hit rate 5 of 6 directional calls best @ T+60▲ +88.41%Jul 7, 2026
Filters
Rows
Reports for SION — sortable, filterable
TypeNow
Aug 10, 2026
7w ago
8-K
BEARISH ★ 7/10
$4.50 $7.30▼ −62.22%▼ −63.14%$5.04 (−12.00%)
Aug 6, 2026
8w ago
8-K
NEUTRAL ★ 4/10
$49.61 $6.75▼ −86.39%▼ −86.99%$5.04 (−89.84%)
Jul 9, 2026
12w ago
Insider Cluster
NEUTRAL ★ 4/10
$45.29 $51.04▲ +12.70%▲ +10.27%$5.04 (−88.87%)
Jul 9, 2026
12w ago
Insider Cluster
BEARISH ★ 5/10
$45.29 $51.04▼ −12.70%▼ −10.27%$5.04 (+88.87%)
Jul 7, 2026
12w ago
Insider Cluster
BEARISH ★ 5/10
$44.00 $47.34▼ −7.59%▼ −4.32%$5.04 (+88.55%)
Jul 2, 2026
13w ago
Insider Cluster
NEUTRAL ★ 4/10
$43.99 $46.78▲ +6.34%▲ +6.76%$5.04 (−88.54%)
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 4/10
$36.05 $44.94▲ +24.66%▲ +22.77%$5.04 (−86.02%)
May 30, 2026
17w ago
Insider Cluster
NEUTRAL ★ 2/10
$40.90 $43.99▲ +7.55%▲ +8.85%$5.04 (−87.68%)
May 29, 2026
17w ago
144
BEARISH ★ 6/10
$40.90 $43.99▼ −7.55%▼ −8.85%$5.04 (+87.68%)
May 12, 2026
20w ago
8-K
NEUTRAL ★ 5/10
$40.94 $34.03▼ −16.88%▼ −15.15%$5.04 (−87.69%)
Showing 10 of 16

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Report published Apr 22, 2026