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144 ·Filed Sep 17, 2026

SION

Sionna Therapeutics, Inc.
BEARISH
Impact 5/10
Horizondays Processed1mo ago SEC0001315082-26-000002
Form 144, notice of proposed sale of securities
Actionable Insight ▼ Bearish

Monitor for actual sale execution on Form 4 and any subsequent insider selling patterns. The large block from a pre-IPO holder could signal reduced conviction ahead of upcoming catalysts or data readouts.

DirectionBearish
Confidencemedium
Horizondays
Latest settled: T+20d
SION ▼ -34.73% at T+20d
SHORT call ✓ call won +34.73% · α vs SPY +34.94% · entry $5.96 → $3.89
Next anchor: T+60d in 6w
Latest observation: T+28 -47.60% FF3 residual α
Entry = T+0 close
Sep 17, 2026
via day close
T+1d
+0.67%
call -0.67% · α +0.88%
$6.00
settled 6w ago
T+5d
-12.25%
call +12.25% · α +13.52%
$5.23
settled 5w ago
T+20d
-34.73%
call +34.73% · α +34.94%
$3.89
settled 15d ago
T+60d
Pending
in 6w

Price Chart

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Executive Summary

RA Capital Healthcare Fund LP, a 10% stockholder of Sionna Therapeutics, filed a Form 144 on September 17, 2026, indicating intent to sell up to 3,448,811 shares of common stock. The filing does not disclose the proposed sale price or dollar value, but the share count represents a material portion of the fund's reported holdings.

Key Facts

  • RA Capital Healthcare Fund LP filed Form 144 to sell up to 3,448,811 shares of Sionna Therapeutics common stock.
  • RA Capital is a 10% stockholder and director of the company.
  • The shares were acquired through private transactions in February 2022, March 2024, and the IPO in February 2025.
  • The filing does not specify the proposed sale price or total dollar value.
  • The sale is planned for the open market via Goldman Sachs & Co.

Financial Impact

3,448,811 shares proposed for sale; dollar value not disclosed in filing.

dilutioninsider selling

Risk Factors

  • Insider selling by a major holder may pressure the stock near-term.
  • Form 144 is an intent to sell; the sale may not occur, but the filing itself signals the insider considered selling.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001315082-26-000002
Document: 0001315082-26-000002-index.html0001315082-26-000002
Document: 0001315082-26-000002.txt0001315082-26-000002
19 reports for SION
Performance horizon
75% Hit rate @ T+5 6 of 8 directional calls Went positive at some point 7 of 8 best @ T+60▲ +89.29%Jul 9, 2026
Filters
Rows
Reports for SION, sortable and filterable
TypeNow
Sep 22, 2026
5w ago
Institutional Cluster
MIXED ★ 3/10
$6.02 $5.15▼ −14.45%▼ −13.26%$3.87 (−35.71%)
Sep 21, 2026
5w ago
SC 13D/A
BEARISH ★ 7/10
$6.02 $5.15▲ +14.45%▲ +13.26%$3.87 (+35.71%)
Sep 17, 2026
6w ago
144
BEARISH ★ 5/10
$5.96 $5.23▲ +12.25%▲ +13.52%$3.87 (+35.07%)
Aug 10, 2026
11w ago
8-K
BEARISH ★ 7/10
$4.50 $5.91▼ −31.33%▼ −31.38%$3.87 (+14.00%)
Aug 6, 2026
12w ago
8-K
NEUTRAL ★ 4/10
$49.61 $6.54▼ −86.82%▼ −88.03%$3.87 (−92.20%)
Jul 9, 2026
16w ago
Insider Cluster
NEUTRAL ★ 4/10
$45.29 $45.29· 0.00%▲ +0.56%$3.87 (−91.46%)
Jul 9, 2026
16w ago
Insider Cluster
BEARISH ★ 5/10
$45.29 $45.29· 0.00%▼ −0.56%$3.87 (+91.46%)
Jul 7, 2026
16w ago
Insider Cluster
BEARISH ★ 5/10
$44.00 $42.59▲ +3.20%▲ +4.07%$3.87 (+91.20%)
Jul 2, 2026
17w ago
Insider Cluster
NEUTRAL ★ 4/10
$43.12 $43.95▲ +1.92%▲ +2.21%$3.87 (−91.03%)
Jun 11, 2026
20w ago
Institutional Cluster
NEUTRAL ★ 4/10
$36.05 $36.73▲ +1.89%▲ +1.45%$3.87 (−89.26%)
Showing 10 of 19

US Market Status

Market Closed · Opens Mon (38h 35m)

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Report published Sep 17, 2026