144 ·Filed Aug 10, 2026

PTGX

Protagonist Therapeutics, Inc
BEARISH
Impact 5/10
Horizonimmediate Processed1mo ago SEC0001968582-26-000805
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

CEO's large proposed sale (~$33.6M) signals potential insider distribution; monitor for actual Form 4 filings to confirm execution. The sale is concurrent with option exercise, suggesting a planned liquidity event rather than a distress signal, but the magnitude relative to market cap is notable. Watch for any subsequent insider selling patterns or changes in guidance.

DirectionBearish
Confidencemedium
Horizonimmediate
Latest settled — T+20d
PTGX ▼ -2.16% at T+20d
SHORT call ✓ call won +2.16% · α vs SPY +1.10% · entry $148.29 → $145.09
Next anchor: T+60d in 5w
Latest observation: T+34 +17.82% FF3 residual α
Entry anchored
Aug 10, 04:00 PM ET
via 1-min bar
T+1d
+2.51%
call -2.51% · α -2.26%
$152.01
settled 7w ago
T+5d
+6.10%
call -6.10% · α -6.51%
$157.34
settled 7w ago
T+20d
-2.16%
call +2.16% · α +1.10%
$145.09
settled 24d ago
T+60d
—
call — · α —
—
in 5w

Price Chart

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Executive Summary

CEO Dinesh Patel filed a Form 144 notice of intent to sell 225,000 shares of Protagonist Therapeutics (PTGX) through J.P. Morgan Securities, with an estimated aggregate market value of approximately $33.6 million based on the filing date. This represents a large proposed sale relative to Patel's remaining holdings of ~64.7 million shares, but the CEO's intent to sell a meaningful stake signals potential insider distribution at a $9.4B market cap company.

Key Facts

  • CEO Dinesh Patel filed Form 144 to sell 225,000 shares of PTGX common stock.
  • Estimated aggregate market value of the proposed sale is $33,583,500.
  • Patel holds approximately 64,708,285 shares after the proposed sale (post-sale holdings).
  • The shares to be sold were acquired via option exercise on August 10, 2026.
  • The sale is planned through J.P. Morgan Securities LLC as agent.
  • The filing date is August 10, 2026; the proposed sale date is also August 10, 2026.

Financial Impact

CEO proposes to sell ~$33.6M worth of stock, representing ~0.35% of market cap and ~0.35% of his post-sale holdings.

insider holdingsdilutionmarket cap

Risk Factors

  • CEO selling a large dollar amount could signal lack of confidence or need for liquidity.
  • The sale may be executed quickly (same-day filing and proposed sale date), increasing near-term selling pressure.
  • If the sale is completed, it could weigh on sentiment given the $9.4B market cap and 90% analyst bullishness.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
90% bullish (20 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001968582-26-000805
Document: 0001968582-26-000805-index.html0001968582-26-000805
Document: 0001968582-26-000805.txt0001968582-26-000805
8 reports for PTGX
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for PTGX — sortable, filterable
TypeNow
Aug 10, 2026
7w ago
144
BEARISH ★ 5/10
$148.29 $145.09▲ +2.16%▲ +1.10%$140.06 (+5.55%)
Jun 18, 2026
15w ago
8-K
NEUTRAL ★ 3/10
$115.03 $140.91▲ +22.50%▲ +22.65%$140.06 (+21.76%)
Jun 12, 2026
16w ago
Institutional Cluster
MIXED ★ 5/10
$109.78 $131.42▲ +19.71%▲ +17.93%$140.06 (+27.58%)
May 12, 2026
20w ago
144
BEARISH ★ 5/10
$103.88 $109.79▼ −5.69%▼ −6.30%$140.06 (−34.83%)
May 8, 2026
21w ago
Insider Cluster
NEUTRAL ★ 4/10
$99.36 $97.38▼ −1.99%▼ −2.02%$140.06 (+40.96%)
May 8, 2026
21w ago
Insider Cluster
NEUTRAL ★ 5/10
$99.36 $97.38▼ −1.99%▼ −2.02%$140.06 (+40.96%)
May 5, 2026
21w ago
8-K
BULLISH ★ 7/10
$103.97 $95.41▼ −8.23%▼ −11.01%$140.06 (+34.71%)
Feb 25, 2026
31w ago
8-K
MIXED ★ 6/10
$87.10 $104.31▲ +19.76%▲ +25.00%$140.06 (+60.80%)
Showing 8 of 8

US Market Status

Market Closed — Opens Mon (64h 22m)

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