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SC 13G/A ·Filed Oct 27, 2026

PTGX

Protagonist Therapeutics, Inc
NEUTRAL
Impact 3/10
Horizonimmediate Processed4d 17h ago SEC0002012383-26-003834
Passive stake amendment
Actionable Insight • Neutral

BlackRock's passive stake increase is routine for a large index fund manager. No prior 13D conversion or activist intent is signaled. Monitor for any future 13D filing if BlackRock's engagement approach changes.

DirectionNeutral
Confidencehigh
Horizonimmediate
Latest settled: T+1d
PTGX ▲ +1.55% at T+1d
NEUTRAL call +1.55% · α vs SPY +1.93% · entry $142.14 → $144.34
Next anchor: T+5d tomorrow
Entry = T+0 close
Oct 27, 2026
via day close
T+1d
+1.55%
call +1.55% · α +1.93%
$144.34
settled 4d ago
T+5d
Pending
tomorrow
T+20d
Pending
in 23d
T+60d
Pending
in 3mo

Price Chart

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Executive Summary

BlackRock filed an amended Schedule 13G disclosing beneficial ownership of 9,834,146 shares of Protagonist Therapeutics common stock, representing 15.2% of outstanding shares as of September 30, 2026. This is a passive stake update; BlackRock's holdings increased from prior filings, but as a passive institutional investor this is a routine disclosure with no directional signal.

Key Financial Metrics

Stake
15.2%
Investor
BlackRock, Inc.
Investor Type
mutual fund

Key Facts

  • BlackRock reported beneficial ownership of 9,834,146 shares of Protagonist Therapeutics common stock as of September 30, 2026
  • The stake represents 15.2% of outstanding shares
  • BlackRock Fund Advisors is the entity that beneficially owns 5% or greater of the outstanding shares
  • The filing is an amendment to a Schedule 13G, indicating passive investment intent
  • BlackRock certifies the securities were acquired and held in the ordinary course of business, not to change or influence control

Financial Impact

BlackRock holds 9,834,146 shares, 15.2% of outstanding shares; at a $9.0B market cap this stake is valued at approximately $1.37B

ownership percentage

Risk Factors

  • No material risks identified from this routine passive stake amendment

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
95% bullish (20 analysts)

Investment Themes

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G/A Filing (Primary)0002012383-26-003834
Document: Item_7.txt0002012383-26-003834
Document: 0002012383-26-003834-index-headers.html0002012383-26-003834
Document: 0002012383-26-003834-index.html0002012383-26-003834
Document: 0002012383-26-003834.txt0002012383-26-003834
9 reports for PTGX
Performance horizon
33% Hit rate @ T+20 1 of 3 directional calls Went positive at some point 3 of 3 best @ T+60▲ +31.42%May 5, 2026
Filters
Rows
Reports for PTGX, sortable and filterable
TypeNow
Oct 27, 2026
4d ago
SC 13G/A
NEUTRAL ★ 3/10
$142.14awaiting T+20awaiting T+20$144.85 (+1.91%)
Aug 10, 2026
11w ago
144
BEARISH ★ 5/10
$148.29 $145.09▲ +2.16%▲ +1.10%$144.85 (+2.32%)
Jun 18, 2026
19w ago
8-K
NEUTRAL ★ 3/10
$115.03 $140.91▲ +22.50%▲ +22.65%$144.85 (+25.92%)
Jun 12, 2026
20w ago
Institutional Cluster
MIXED ★ 5/10
$109.78 $131.42▲ +19.71%▲ +17.93%$144.85 (+31.95%)
May 12, 2026
24w ago
144
BEARISH ★ 5/10
$103.88 $109.79▼ −5.69%▼ −6.30%$144.85 (−39.44%)
May 8, 2026
25w ago
Insider Cluster
NEUTRAL ★ 4/10
$99.36 $97.38▼ −1.99%▼ −2.02%$144.85 (+45.78%)
May 8, 2026
25w ago
Insider Cluster
NEUTRAL ★ 5/10
$99.36 $97.38▼ −1.99%▼ −2.02%$144.85 (+45.78%)
May 5, 2026
25w ago
8-K
BULLISH ★ 7/10
$103.97 $95.41▼ −8.23%▼ −11.01%$144.85 (+39.32%)
Feb 25, 2026
35w ago
8-K
MIXED ★ 6/10
$88.39 $102.17▲ +15.59%▲ +22.00%$144.85 (+63.88%)
Showing 9 of 9

US Market Status

Market Closed · Opens Mon (23h 43m)

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Report published Oct 27, 2026