Insider Cluster (7 insiders) ·Filed Feb 25, 2026

VRTX

VERTEX PHARMACEUTICALS INC / MA
NEUTRAL
Impact 4/10
Horizondays Processed7mo ago
Insider cluster: 5 insiders, $2.4M total
Actionable Insight • Neutral

Monitor for next earnings release or pipeline updates; this cluster reflects routine post-vesting tax management, not a bearish signal. No abnormal selling pressure observed.

DirectionNeutral
Confidencehigh
Horizondays
Final — all horizons settled through T+60d ⚠ clustered
VRTX ▼ -10.87% at T+60d
NEUTRAL call ✗ call lost -10.87% · α vs SPY -17.82% · entry $482.92 → $430.44
Entry anchored
Feb 24, 03:59 PM ET
via exchange tick
T+1d
-0.58%
call -0.58% · α -0.03%
$480.12
settled 7mo ago
T+5d
-1.32%
call -1.32% · α -0.22%
$476.54
settled 7mo ago
T+20d
-5.79%
call -5.79% · α -0.55%
$454.96
settled 6mo ago
T+60d
-10.87%
call -10.87% · α -17.82%
$430.44
settled 5mo ago

Price Chart

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Executive Summary

Seven Vertex Pharmaceuticals executives sold shares in the past week, including open-market sales totaling $2.3M and tax-related share withholdings worth $7.3M. The activity is primarily driven by routine tax settlements following vesting events, not discretionary selling.

Key Financial Metrics

Direction
selling
Total Value
$2.3M
Insiders
7

Key Facts

  • Five executives conducted open-market sales totaling $2.31M in the past two days.
  • All seven insiders also surrendered shares for tax withholding totaling $7.31M, including CEO Reshma Kewalramani ($2.42M) and Executive Chairman Jeffrey Leiden ($1.72M).
  • Tax withholdings accounted for ~76% of total transaction value in the cluster.
  • Total economic value of open-market sales is 0.0019% of VRTX's $122.5B market cap — immaterial in scale.
  • No purchases or negative disclosures (e.g., downgrades, restatements) accompany the filings.

Financial Impact

$2.31M in open-market sales and $7.31M in tax withholdings over 7 days

insider ownershipshare count

Risk Factors

  • Perception risk if investors misinterpret tax withholdings as active selling.
  • Future insider selling above 0.1% of market cap could signal concern.

Market Snapshot

Exchange
Nasdaq

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (13 trades, 7d window)cluster-VRTX-1772149724915
11 reports for VRTX
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for VRTX — sortable, filterable
TypeNow
Jul 7, 2026
12w ago
8-K
BULLISH ★ 7/10
$522.25 $522.81▲ +0.11%▼ −1.89%$506.74 (−2.97%)
Jul 7, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$522.25 $522.81▲ +0.11%▼ −1.89%$506.74 (−2.97%)
Jul 6, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$529.59 $526.73▼ −0.54%▼ −2.26%$506.74 (−4.31%)
Jun 3, 2026
17w ago
Insider Cluster
NEUTRAL ★ 2/10
$441.47 $541.69▲ +22.70%▲ +21.08%$506.74 (+14.79%)
May 19, 2026
19w ago
Insider Cluster
NEUTRAL ★ 2/10
$430.05 $505.75▲ +17.60%▲ +12.87%$506.74 (+17.83%)
Mar 11, 2026
29w ago
Insider Cluster
NEUTRAL ★ 3/10
$491.96 $428.34▼ −12.93%▼ −24.45%$506.74 (+3.01%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 4/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Feb 25, 2026
31w ago
Insider Cluster
BEARISH ★ 6/10
$482.92 $430.44▲ +10.87%▲ +17.82%$506.74 (−4.93%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 3/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 4/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Showing 10 of 11

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Report published Feb 26, 2026