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Institutional Cluster ·Filed Oct 16, 2026

VRTX

VERTEX PHARMACEUTICALS INC / MA
BULLISH
Impact 4/10
Horizonweeks Processed10d 2h ago
Institutional cluster: 3 buyers, 1 sellers (bullish)
Actionable Insight ▲ Bullish

Monitor VRTX for a catalyst that may have driven this Q3 accumulation (e.g., pipeline updates, FDA decisions, or earnings). The 45-day reporting lag means the cluster may have already been unwound; watch for insider buying or recent 13D filings to confirm conviction.

DirectionBullish
Confidencemedium
Horizonweeks
Latest settled — T+5d
VRTX ▲ +3.42% at T+5d
LONG call ✓ call won +3.42% · α vs SPY +3.57% · entry $500.36 → $517.49
Next anchor: T+20d in 17d
Entry = T+0 close
Oct 16, 2026
via day close
T+1d
+2.46%
call +2.46% · α +2.13%
$512.69
settled 8d ago
T+5d
+3.42%
call +3.42% · α +3.57%
$517.49
settled 4d ago
T+20d
Pending
in 17d
T+60d
Pending
in 3mo

Executive Summary

Three asset managers added to their VRTX positions in Q3 2026, led by a $260M increase from Assenagon Asset Management, while one small seller trimmed.

Key Financial Metrics

Direction
accumulating
Buy Value
$664.8M
Sell Value
$6.8M
Net Flow
$261.6M

Institutional Positions

Net institutional flow: $261.6M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
Assenagon Asset ManagementADD+60.5%$637.5M$260.2M
Wealth Enhancement Advisory ServicesADD+54.5%$22.4M$921.0K
Farther Finance AdvisorsADD+92.4%$5.0M$2.5M

▼ Sellers (1)

InstitutionActionChangePrev ValueValue Δ
Td Waterhouse CanadaTRIM-30.3%$6.8M-$2.0M

Key Facts

  • Three asset managers added VRTX positions totaling $664.8M in current holdings, up $263.6M from prior quarter.
  • Assenagon Asset Management was the largest buyer, increasing its stake by $260.2M (+60.5% shares).
  • Only one small seller (Td Waterhouse Canada) trimmed $2.0M, a negligible offset.
  • All buyers are active asset managers, not passive index funds, strengthening the signal.

Financial Impact

3 institutions accumulated $263.6M in net new VRTX positions while 1 institution reduced holdings by $2.0M, for a net inflow of approximately $261.6M.

institutional ownershipfloat

Risk Factors

  • 13F data is 45+ days stale; positions may have been reduced since quarter-end.
  • Only 3 buyers — cluster size is small; not a broad institutional consensus.

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-VRTX-2026-Q3
14 reports for VRTX
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for VRTX — sortable, filterable
TypeNow
Oct 22, 2026
4d ago
3
NEUTRAL ★ 2/10
$523.93awaiting T+5——
Oct 20, 2026
6d ago
8-K
NEUTRAL ★ 2/10
$524.52awaiting T+5——
Oct 16, 2026
10d ago
Institutional Cluster
BULLISH ★ 4/10
$500.36 $517.49▲ +3.42%▲ +3.57%—
Jul 7, 2026
15w ago
Insider Cluster
NEUTRAL ★ 2/10
$498.43 $477.08▼ −4.28%▼ −5.55%—
Jul 6, 2026
15w ago
8-K
BULLISH ★ 7/10
$522.25 $476.31▼ −8.80%▼ −9.35%—
Jul 6, 2026
16w ago
Insider Cluster
NEUTRAL ★ 2/10
$522.25 $476.31▼ −8.80%▼ −9.35%—
Jun 3, 2026
20w ago
Insider Cluster
NEUTRAL ★ 2/10
$441.47 $445.04▲ +0.81%▲ +3.36%—
May 19, 2026
22w ago
Insider Cluster
NEUTRAL ★ 2/10
$430.05 $447.70▲ +4.10%▲ +2.30%—
Mar 11, 2026
32w ago
Insider Cluster
NEUTRAL ★ 3/10
$491.96 $451.61▼ −8.20%▼ −6.01%—
Feb 25, 2026
34w ago
Insider Cluster
NEUTRAL ★ 4/10
$482.92 $476.54▼ −1.32%▼ −0.22%—
Showing 10 of 14

US Market Status

Market Closed — Opens Wed (12h 44m)

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Report published Oct 16, 2026