Insider Cluster (2 insiders) ·Filed Feb 25, 2026

VRTX

VERTEX PHARMACEUTICALS INC / MA
NEUTRAL
Impact 3/10
Horizondays Processed7mo ago
Insider cluster: 2 insiders, $433K total
Actionable Insight • Neutral

Monitor for additional selling in the coming weeks — isolated transactions of this size are routine, but continued outflows could signal caution. Tax-related share surrenders are standard with RSU vesting and not a negative signal.

DirectionNeutral
Confidencehigh
Horizondays
Final — all horizons settled through T+60d ⚠ clustered
VRTX ▼ -10.87% at T+60d
NEUTRAL call ✗ call lost -10.87% · α vs SPY -17.82% · entry $482.92 → $430.44
Entry anchored
Feb 24, 03:59 PM ET
via exchange tick
T+1d
-0.58%
call -0.58% · α -0.03%
$480.12
settled 7mo ago
T+5d
-1.32%
call -1.32% · α -0.22%
$476.54
settled 7mo ago
T+20d
-5.79%
call -5.79% · α -0.55%
$454.96
settled 6mo ago
T+60d
-10.87%
call -10.87% · α -17.82%
$430.44
settled 5mo ago

Price Chart

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Executive Summary

Two executives at Vertex Pharmaceuticals executed open-market share sales totaling $433K, while the same insiders also surrendered shares for tax withholding purposes related to equity compensation. The open-market sales are modest in value relative to the company's $122.5B market cap.

Key Financial Metrics

Direction
selling
Total Value
$433.3K
Insiders
2

Key Facts

  • EVP Edward Atkinson sold 668 shares for $324,881.80 in an open-market transaction.
  • SVP Kristen Ambrose sold 223 shares for $108,456.05 in an open-market transaction.
  • Both executives also surrendered shares to cover tax liabilities from equity vesting: Atkinson (1,627 shares, $789,273.97) and Ambrose (546 shares, $264,870.06).
  • Total open-market proceeds: $433,337.85; total tax-related share surrenders: ~$1.05M.
  • All transactions occurred between February 24–25, 2026.

Financial Impact

$433K in net open-market selling by two executives; $1.05M in non-cash tax withholding transactions

insider ownershipshare count

Risk Factors

  • Perception of insider selling may weigh on sentiment if misinterpreted
  • Concentration of selling among C-suite executives, though small in dollar terms

Market Snapshot

Exchange
Nasdaq

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (4 trades, 7d window)cluster-VRTX-1772146834885
11 reports for VRTX
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for VRTX — sortable, filterable
TypeNow
Jul 7, 2026
12w ago
8-K
BULLISH ★ 7/10
$522.25 $522.81▲ +0.11%▼ −1.89%$506.74 (−2.97%)
Jul 7, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$522.25 $522.81▲ +0.11%▼ −1.89%$506.74 (−2.97%)
Jul 6, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$529.59 $526.73▼ −0.54%▼ −2.26%$506.74 (−4.31%)
Jun 3, 2026
17w ago
Insider Cluster
NEUTRAL ★ 2/10
$441.47 $541.69▲ +22.70%▲ +21.08%$506.74 (+14.79%)
May 19, 2026
19w ago
Insider Cluster
NEUTRAL ★ 2/10
$430.05 $505.75▲ +17.60%▲ +12.87%$506.74 (+17.83%)
Mar 11, 2026
29w ago
Insider Cluster
NEUTRAL ★ 3/10
$491.96 $428.34▼ −12.93%▼ −24.45%$506.74 (+3.01%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 4/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Feb 25, 2026
31w ago
Insider Cluster
BEARISH ★ 6/10
$482.92 $430.44▲ +10.87%▲ +17.82%$506.74 (−4.93%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 3/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Feb 25, 2026
31w ago
Insider Cluster
NEUTRAL ★ 4/10
$482.92 $430.44▼ −10.87%▼ −17.82%$506.74 (+4.93%)
Showing 10 of 11

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Report published Feb 26, 2026