The drop below 5% signals Decheng Capital is reducing its position, though the fund remains a notable holder. Monitor for further reductions or a potential exit, which could add selling pressure.
Price Chart
Executive Summary
Decheng Capital Global Life Sciences Fund IV, L.P. filed an amended Schedule 13G disclosing a 4.9% passive stake (2,724,868 shares) in Upstream Bio, Inc. as of September 30, 2026, down from a prior 5%+ position. The filing includes a joint filing agreement among the fund, its general partner, and its manager.
Key Financial Metrics
Key Facts
- Decheng Capital Global Life Sciences Fund IV, L.P. holds 2,724,868 shares of Upstream Bio common stock.
- The stake represents 4.9% of shares outstanding based on 54,771,041 shares outstanding as of August 4, 2026.
- The filing is an amendment to Schedule 13G, indicating passive investor status.
- The stake decreased from a prior filing where it was above 5% (now below the 5% threshold).
- Reporting persons include Decheng Capital Management IV (Cayman), LLC and Xiangmin Cui.
Financial Impact
Stake valued at approximately $7.5M based on $153M market cap and 4.9% ownership.
Risk Factors
- Continued selling by Decheng Capital could pressure the stock.
- Passive filing status means no activist engagement is expected from this holder.
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 4 SEC documents filed with EDGAR.
| Document | Accession Number |
|---|---|
| SC 13G/A Filing (Primary) | 0001834150-26-000006 |
| Document: 0001834150-26-000006-index-headers.html | 0001834150-26-000006 |
| Document: 0001834150-26-000006-index.html | 0001834150-26-000006 |
| Document: 0001834150-26-000006.txt | 0001834150-26-000006 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Oct 29, 2026 3d ago | SC 13G/A | $3.00 | awaiting T+60 | awaiting T+60 | $3.41 (+13.67%) |
Sep 1, 2026 8w ago | 8-K | $6.55 | awaiting T+60 | awaiting T+60 | $3.41 (−47.94%) |
Aug 11, 2026 11w ago | 8-K | $7.44 | awaiting T+60 | awaiting T+60 | $3.41 (−54.17%) |
Jun 17, 2026 19w ago | Insider Cluster | $6.25 | awaiting T+60 | awaiting T+60 | $3.41 (−45.44%) |
Jun 14, 2026 20w ago | Press Release | $6.10 $5.96 | ▼ −2.30% | ▼ −3.30% | $3.41 (−44.10%) |
May 18, 2026 23w ago | Press Release | $8.51 $6.91 | ▼ −18.80% | ▼ −23.65% | $3.41 (−59.93%) |
May 13, 2026 24w ago | Press Release | $9.36 $7.25 | ▲ +22.54% | ▲ +26.98% | $3.41 (+63.57%) |
Apr 17, 2026 28w ago | Press Release | $9.99 $7.14 | ▼ −28.53% | ▼ −34.67% | $3.41 (−65.87%) |
Mar 26, 2026 31w ago | 424B5 | $8.67 $6.41 | ▲ +26.07% | ▲ +42.13% | $3.41 (+60.67%) |
Mar 26, 2026 31w ago | Press Release | $9.79 $6.40 | ▼ −34.68% | ▼ −48.63% | $3.41 (−65.17%) |
US Market Status
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