424B5 ·Filed Aug 4, 2026

TYRA

Tyra Biosciences, Inc.
BEARISH
Impact 6/10
Horizonweeks Processed1mo ago SEC0001193125-26-333055
Notable filing: 424B5
Actionable Insight ▼ Bearish

The expanded ATM facility creates a persistent overhang; monitor daily volume and TD Cowen's selling activity for signs of accelerated distribution. With high short interest, any positive pipeline catalyst could trigger a squeeze, but the ATM cap increase suggests management expects to need more cash, likely capping near-term upside.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+20d
TYRA ▼ -2.26% at T+20d
SHORT call ✓ call won +2.26% · α vs SPY +1.65% · entry $25.71 → $25.13
Next anchor: T+60d in 26d
Latest observation: T+38 +40.72% FF3 residual α
Entry anchored
Aug 4, 03:59 PM ET
via exchange tick
T+1d
+4.86%
call -4.86% · α -5.02%
$26.96
settled 8w ago
T+5d
-1.59%
call +1.59% · α +1.95%
$25.30
settled 7w ago
T+20d
-2.26%
call +2.26% · α +1.65%
$25.13
settled 4w ago
T+60d
—
call — · α —
—
in 26d

Price Chart

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Executive Summary

Tyra Biosciences has amended its existing at-the-market (ATM) equity offering agreement with TD Cowen, increasing the maximum aggregate offering amount from $150 million to $250 million after fully utilizing the prior $150 million capacity. The filing signals ongoing dilution risk for existing shareholders as the company continues to access the public equity markets for capital, likely to fund its clinical-stage pipeline. With a $1.9B market cap and high short interest (~16.7%), the market may view this expanded ATM capacity as a near-term overhang on the stock.

Key Facts

  • Tyra Biosciences has fully utilized its prior $150 million ATM facility and amended the agreement to allow up to $250 million in total common stock sales.
  • The amendment was entered into on August 4, 2026, and the last reported sale price on August 3, 2026 was $32.04 per share.
  • The company is a clinical-stage biopharmaceutical firm with no disclosed revenue in this filing, relying on equity offerings for capital.
  • Short interest is approximately 16.7% of estimated shares outstanding as of mid-July 2026, indicating significant bearish positioning.

Financial Impact

Potential dilution of up to ~$100 million in additional common stock sales beyond the already-exhausted $150 million facility, representing roughly 5-8% of current market cap at the $32.04 reference price.

dilutionshare countmarket cap

Risk Factors

  • Continued dilution from ATM sales may pressure the stock price.
  • Clinical-stage biotech with no revenue; capital needs are uncertain and may require further equity raises.
  • High short interest could amplify downside if the ATM is used aggressively.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
91% bullish (22 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
424B5 Filing (Primary)0001193125-26-333055
Document: 0001193125-26-333055-index-headers.html0001193125-26-333055
Document: 0001193125-26-333055-index.html0001193125-26-333055
Document: 0001193125-26-333055.txt0001193125-26-333055
9 reports for TYRA
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for TYRA — sortable, filterable
TypeNow
Sep 14, 2026
18d ago
S-3ASR
NEUTRAL ★ 3/10
$25.07 $25.65▲ +2.31%▲ +2.21%$20.50 (−18.21%)
Sep 9, 2026
23d ago
8-K
BULLISH ★ 6/10
$22.01 $24.35▲ +10.63%▲ +11.73%$20.50 (−6.84%)
Aug 4, 2026
8w ago
424B5
BEARISH ★ 6/10
$25.71 $25.30▲ +1.59%▲ +1.95%$20.50 (+20.25%)
Jun 26, 2026
13w ago
144
BEARISH ★ 6/10
$32.11 $30.86▲ +3.89%▲ +5.28%$20.50 (+36.14%)
May 13, 2026
20w ago
8-K
MIXED ★ 5/10
$36.19 $33.78▼ −6.66%▼ −5.50%$20.50 (−43.34%)
Apr 20, 2026
23w ago
3
NEUTRAL ★ 2/10
$36.69 $35.06▼ −4.44%▼ −5.53%$20.50 (−44.11%)
Apr 17, 2026
24w ago
DEFA14A
NEUTRAL ★ 4/10
$35.56 $37.59▲ +5.71%▲ +5.15%$20.50 (−42.34%)
Apr 17, 2026
24w ago
8-K
NEUTRAL ★ 3/10
$35.56 $37.59▲ +5.71%▲ +5.15%$20.50 (−42.34%)
Apr 13, 2026
24w ago
144
NEUTRAL ★ 2/10
$35.27 $36.69▲ +4.03%▲ +2.63%$20.50 (−41.86%)
Showing 9 of 9

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