A 10% owner deploying 61% of market cap into open-market stock is an extreme conviction signal. Watch for a near-term catalyst (data readout, partnership, or M&A) that RA Capital may be anticipating.
Price Chart
Executive Summary
Two Tyra Biosciences insiders, including 10% owner RA Capital Management, made open-market purchases totaling $200.01M from September 8-15, 2026. The $199.99M purchase by RA Capital alone represents approximately 61% of the company's $326M market cap, an extraordinarily large and concentrated bullish signal from a sophisticated healthcare investor.
Key Financial Metrics
Key Facts
- RA Capital Management (Director, 10% Owner) purchased 9.08M shares at $22.03 for $199.99M on 2026-09-15
- Director Rehan Verjee purchased 972 shares at $20.58 for $20K on 2026-09-09
- Total cluster value: $200.01M, all open-market purchases (code P)
- RA Capital's purchase alone equals ~61% of Tyra's $326M market cap
- No 10b5-1 plan indication; both trades are voluntary open-market buys
Financial Impact
RA Capital's $199.99M purchase is ~61% of market cap, the largest insider buy relative to company size in the cluster dataset
Risk Factors
- RA Capital may be averaging into a larger strategic position rather than signaling near-term news
- Biotech binary catalysts (FDA, trial data) carry inherent downside risk regardless of insider buying
Investment Themes
Documents Analyzed
This report is based on 1 SEC document filed with EDGAR.
| Document | Accession Number |
|---|---|
| CLUSTER Data (Synthetic) | cluster-TYRA-1789708822534 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Sep 21, 2026 5w ago | SC 13G | $25.57 $21.98 | ▼ −14.04% | ▼ −12.85% | $20.42 (−20.14%) |
Sep 17, 2026 5w ago | Insider Cluster | $25.73 $21.76 | ▼ −15.43% | ▼ −16.70% | $20.42 (−20.64%) |
Sep 14, 2026 6w ago | S-3ASR | $25.07 $25.65 | ▲ +2.31% | ▲ +2.21% | $20.42 (−18.55%) |
Sep 9, 2026 6w ago | 8-K | $22.01 $24.35 | ▲ +10.63% | ▲ +11.73% | $20.42 (−7.22%) |
Aug 4, 2026 11w ago | 424B5 | $25.71 $25.30 | ▲ +1.59% | ▲ +1.95% | $20.42 (+20.58%) |
Jun 26, 2026 17w ago | 144 | $32.11 $30.86 | ▲ +3.89% | ▲ +5.28% | $20.42 (+36.41%) |
May 13, 2026 23w ago | 8-K | $36.19 $33.78 | ▼ −6.66% | ▼ −5.50% | $20.42 (−43.58%) |
Apr 20, 2026 27w ago | 3 | $36.69 $35.06 | ▼ −4.44% | ▼ −5.53% | $20.42 (−44.34%) |
Apr 17, 2026 27w ago | DEFA14A | $35.56 $37.59 | ▲ +5.71% | ▲ +5.15% | $20.42 (−42.58%) |
Apr 17, 2026 27w ago | 8-K | $35.56 $37.59 | ▲ +5.71% | ▲ +5.15% | $20.42 (−42.58%) |
US Market Status
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