PRESS-RELEASE ·Filed May 14, 2026

PYXS

Pyxis Oncology
NEUTRAL
Impact 4/10
Horizonweeks Processed4mo ago WireGlobeNewswire
Press release: earnings
Actionable Insight • Neutral

Monitor upcoming MICVO data readouts (mid-2026 and 2H26) for potential catalysts; limited cash runway suggests financing risk if trials delay.

DirectionNeutral
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
PYXS ▲ +73.30% at T+60d
NEUTRAL call ✓ call won +73.30% · α vs SPY +69.71% · entry $2.21 → $3.83
Entry anchored
May 14, 2026
via day open
T+1d
+3.17%
call +3.17% · α +4.39%
$2.28
settled 5mo ago
T+5d
-12.22%
call -12.22% · α -11.50%
$1.94
settled 4mo ago
T+20d
-20.36%
call -20.36% · α -19.50%
$1.76
settled 4mo ago
T+60d
+73.30%
call +73.30% · α +69.71%
$3.83
settled 7w ago

Price Chart

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Executive Summary

Pyxis Oncology reported Q1 2026 EPS of -$0.37, missing consensus of -$0.35 by 5.7%. The clinical-stage biotech has $42.5M cash runway into Q4 2026 and reiterated MICVO Phase 1 monotherapy data for mid-2026 and combination data for 2H26. The modest earnings miss is typical for pre-revenue companies and overshadowed by pipeline milestones.

Key Financial Metrics

EPS
$-0.37
est $-0.35 · -5.7%
Revenue
$0.00
est $0.00
Rating
miss

Key Facts

  • Q1 2026 EPS -$0.37 vs consensus -$0.35 (5.7% miss)
  • Cash and investments $42.5M, runway into Q4 2026
  • MICVO Phase 1 monotherapy update expected mid-2026, combination data 2H26
  • No revenue (clinical-stage biotech)

Financial Impact

Net loss of $23.3M in Q1 2026, up from $21.2M in Q1 2025; cash burn $42.5M remaining

epscashnet loss

Risk Factors

  • Cash runway only into Q4 2026, possible dilution if milestones slip
  • Clinical trial failure risk for MICVO
  • Pre-revenue stage with no near-term revenue prospects

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
87% bullish (15 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3294764
12 reports for PYXS
Performance horizon
67% Hit rate 2 of 3 directional calls best @ T+60▲ +42.94%Apr 17, 2026
Filters
Rows
Reports for PYXS — sortable, filterable
TypeNow
Sep 9, 2026
23d ago
8-K
BULLISH ★ 6/10
$3.38 $3.34▼ −1.18%▼ −0.09%$2.14 (−36.54%)
Sep 8, 2026
24d ago
8-K
NEUTRAL ★ 3/10
$3.89 $3.33▼ −14.40%▼ −13.28%$2.14 (−44.86%)
Aug 28, 2026
5w ago
EFFECT
BEARISH ★ 6/10
$3.23 $3.89▼ −20.43%▼ −20.32%$2.14 (+33.59%)
Aug 13, 2026
7w ago
8-K
MIXED ★ 5/10
$3.01 $3.12▲ +3.65%▲ +5.62%$2.14 (−28.74%)
Jul 2, 2026
13w ago
8-K
MIXED ★ 6/10
$2.63 $2.64▲ +0.38%▼ −0.55%$2.14 (−18.44%)
Jun 30, 2026
13w ago
144
NEUTRAL ★ 2/10
$2.85 $3.07▲ +7.72%▲ +7.46%$2.14 (−24.74%)
Jun 30, 2026
13w ago
Press Release
MIXED ★ 6/10
$3.01 $2.46▼ −18.27%▼ −18.88%$2.14 (−28.74%)
May 14, 2026
20w ago
8-K
NEUTRAL ★ 5/10
$2.21 $1.94▼ −12.22%▼ −11.50%$2.14 (−2.94%)
May 14, 2026
20w ago
Press Release
NEUTRAL ★ 4/10
$2.21 $1.94▼ −12.22%▼ −11.50%$2.14 (−2.94%)
Apr 30, 2026
22w ago
DEFA14A
NEUTRAL ★ 2/10
$1.70 $2.26▲ +32.94%▲ +31.21%$2.14 (+26.18%)
Showing 10 of 12

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Report published May 14, 2026