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DEF 14A ·Filed Oct 21, 2026

PYXS

Pyxis Oncology, Inc.
BEARISH
Impact 6/10
Horizonweeks Processed5d 18h ago SEC0001193125-26-427882
Definitive proxy statement
Actionable Insight ▼ Bearish

The vote outcome is critical — if the charter amendment fails, the 49.3M common warrants become worthless, which could trigger a sharp sell-off from warrant holders and potentially impair the company's ability to raise future capital. Monitor proxy advisory firm recommendations (ISS/Glass Lewis) and early vote tallies. The special meeting is November 13, 2026.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+1d
PYXS ▼ -1.75% at T+1d
SHORT call ✓ call won +1.75% · α vs SPY +1.23% · entry $1.71 → $1.68
Next anchor: T+5d in 21h
Entry = T+0 close
Oct 21, 2026
via day close
T+1d
-1.75%
call +1.75% · α +1.23%
$1.68
settled 5d ago
T+5d
Pending
in 21h
T+20d
Pending
in 22d
T+60d
Pending
in 3mo

Price Chart

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Executive Summary

Pyxis Oncology is holding a special meeting on November 13, 2026 to seek stockholder approval to double its authorized common shares from 190M to 380M. The increase is needed to allow exercise of 49.3M common warrants issued in an October 1, 2026 underwritten offering. Without approval, those warrants would be worthless. The filing also includes an adjournment proposal to solicit additional votes if needed.

Key Facts

  • Proposes to increase authorized common shares from 190,000,000 to 380,000,000 (2x increase)
  • 119,583,637 shares outstanding as of October 8, 2026 record date
  • October 1, 2026 offering sold 36,047,919 shares + 1,883,121 pre-funded warrants + 49,310,352 common warrants
  • Only ~27.6M authorized shares remain available; insufficient to permit warrant exercise
  • If charter amendment fails, the 49.3M common warrants will not be exercisable and may have no value
  • Board can abandon the amendment even if stockholders approve
  • Five 5%+ holders: GordonMD (16.4%), BVF (9.99%), RTW (8.4%), OrbiMed (7.2%), Pfizer (5.9%)
  • Insiders and directors as a group own 10.5% of outstanding shares

Financial Impact

Potential dilution of up to ~41% if all 49.3M warrants are exercised on top of the 36M shares already issued in the October 1 offering. The company is a clinical-stage oncology company with no disclosed revenue, so dilution is the primary financial impact.

dilutionshare countvoting power

Risk Factors

  • Charter amendment fails → warrants worthless, potential stock price decline
  • Massive dilution if all warrants exercised (up to 49.3M additional shares)
  • Clinical-stage biotech with no disclosed revenue; dependent on capital markets
  • Board can abandon amendment even if approved, creating uncertainty
  • Anti-takeover potential: increased authorized shares could be used to dilute hostile bidders

Investment Themes

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
DEF 14A Filing (Primary)0001193125-26-427882
Document: 0001193125-26-427882-index-headers.html0001193125-26-427882
Document: 0001193125-26-427882-index.html0001193125-26-427882
Document: 0001193125-26-427882.txt0001193125-26-427882
20 reports for PYXS
Performance horizon
71% Hit rate @ T+5 5 of 7 directional calls Went positive at some point 6 of 7 best @ T+60▲ +42.94%Apr 17, 2026
Filters
Rows
Reports for PYXS — sortable, filterable
TypeNow
Oct 27, 2026
today
Press Release
NEUTRAL ★ 4/10
$1.66awaiting T+5—$1.74 (+4.52%)
Oct 21, 2026
5d ago
DEF 14A
BEARISH ★ 6/10
$1.71awaiting T+5—$1.74 (−1.46%)
Oct 9, 2026
17d ago
SC 13G/A
NEUTRAL ★ 4/10
$2.03 $1.68▼ −17.24%▼ −15.27%$1.74 (−14.53%)
Oct 2, 2026
25d ago
SC 13G/A
NEUTRAL ★ 4/10
$2.14 $2.03▼ −5.14%▼ −6.30%$1.74 (−18.93%)
Oct 2, 2026
25d ago
Press Release
BEARISH ★ 7/10
$2.14 $2.03▲ +5.14%▲ +6.30%$1.74 (+18.93%)
Oct 1, 2026
25d ago
8-K
BEARISH ★ 7/10
$2.14 $2.03▲ +5.14%▲ +6.30%$1.74 (+18.93%)
Oct 1, 2026
26d ago
424B5
BEARISH ★ 6/10
$2.19 $1.99▲ +9.13%▲ +10.43%$1.74 (+20.78%)
Sep 30, 2026
27d ago
Press Release
BEARISH ★ 7/10
$2.33 $2.01▲ +13.73%▲ +15.65%$1.74 (+25.54%)
Sep 9, 2026
6w ago
8-K
BULLISH ★ 6/10
$3.38 $3.34▼ −1.18%▼ −0.09%$1.74 (−48.67%)
Sep 8, 2026
7w ago
8-K
NEUTRAL ★ 3/10
$3.89 $3.33▼ −14.40%▼ −13.28%$1.74 (−55.40%)
Showing 10 of 20

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Report published Oct 21, 2026