Insider Buy ·Filed Sep 3, 2026

PRTA

PROTHENA CORP PUBLIC LTD CO
NEUTRAL
Impact 3/10
Horizonweeks Processed28d 20h ago SEC0001045463-26-000015
Insider cluster: 1 insiders, $256K total
Actionable Insight • Neutral

The purchase is too small relative to market cap to be a strong standalone signal, but the insider's 10% owner status and recent buying pattern warrant monitoring. Watch for additional insider purchases or a material catalyst (e.g., pipeline update, partnership) that could confirm the bullish view. The next catalyst to watch is the upcoming earnings or clinical data readout.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+5d ⚠ clustered
PRTA ▼ -9.78% at T+5d
NEUTRAL call ✗ call lost -9.78% · α vs SPY -8.57% · entry $9.82 → $8.86
Next anchor: T+20d due 7h ago
Latest observation: T+18 -11.42% FF3 residual α
Entry anchored
Sep 3, 04:00 PM ET
via 1-min bar
T+1d
-2.85%
call -2.85% · α -2.30%
$9.54
settled 28d ago
T+5d
-9.78%
call -9.78% · α -8.57%
$8.86
settled 21d ago
T+20d
—
call — · α —
—
due 7h ago
T+60d
—
call — · α —
—
in 8w

Price Chart

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Executive Summary

William P. Scully, a 10% owner of Prothena, purchased 27,000 shares on the open market for approximately $256K at $9.47/share. This is a standalone conviction buy from a major insider, representing about 0.05% of the company's $497M market cap, which is below the 0.1% threshold for materiality. The purchase is modest in size relative to market cap, but the insider's status as a 10% owner and the recent cluster of insider buys ($1.0M over 30 days) add some weight, though historical performance on PRTA insider-buy signals has been mixed with a 50% win rate at T+20.

Key Financial Metrics

Direction
buying
Total Value
$255.7K
Insiders
1

Key Facts

  • 10% owner William P. Scully purchased 27,000 shares at $9.47/share for $256K on 2026-09-02.
  • The purchase represents ~0.05% of PRTA's $497M market cap, below the 0.1% materiality threshold.
  • This is a single insider buy, not a cluster; the broader 30-day insider activity shows $1.0M in total buys.
  • Historical PRTA insider-buy signals have a 50% win rate at T+20 with an average alpha of +0.21% vs SPY.

Financial Impact

$256K open-market purchase by 10% owner, representing ~0.05% of market cap

insider ownership

Risk Factors

  • Purchase is modest at 0.05% of market cap, limiting its signaling power.
  • Historical insider-buy signals on PRTA have been mixed, with a 50% win rate at T+20.
  • No accompanying material corporate event (e.g., earnings, pipeline update) to contextualize the buy.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
67% bullish (12 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
INSIDER-BUY Data (Synthetic)0001045463-26-000015
10 reports for PRTA
Performance horizon
60% Hit rate 3 of 5 directional calls best @ T+60▲ +14.11%Jun 12, 2026
Filters
Rows
Reports for PRTA — sortable, filterable
TypeNow
Sep 3, 2026
28d ago
Insider Buy
NEUTRAL ★ 3/10
$9.82 $8.86▼ −9.78%▼ −8.57%$8.44 (−14.05%)
Aug 21, 2026
6w ago
Insider Buy
BULLISH ★ 4/10
$9.45 $9.33▼ −1.27%▼ −1.74%$8.44 (−10.69%)
Aug 10, 2026
7w ago
Insider Buy
BULLISH ★ 5/10
$9.12 $8.88▼ −2.63%▼ −2.58%$8.44 (−7.46%)
Jul 31, 2026
9w ago
Insider Cluster
NEUTRAL ★ 2/10
$8.12 $8.76▲ +7.88%▲ +4.37%$8.44 (+3.94%)
Jun 18, 2026
15w ago
Insider Buy
BULLISH ★ 5/10
$8.93 $9.27▲ +3.81%▲ +5.47%$8.44 (−5.49%)
Jun 12, 2026
15w ago
Insider Buy
BULLISH ★ 5/10
$8.15 $9.15▲ +12.27%▲ +13.65%$8.44 (+3.56%)
May 14, 2026
20w ago
3
NEUTRAL ★ 2/10
$9.76 $9.83▲ +0.72%▼ −0.25%$8.44 (−13.52%)
May 7, 2026
21w ago
8-K
BULLISH ★ 8/10
$10.73 $9.86▼ −8.11%▼ −9.57%$8.44 (−21.34%)
Mar 27, 2026
26w ago
DEFA14A
NEUTRAL ★ 3/10
$9.25 $10.36▲ +12.00%▲ +7.70%$8.44 (−8.76%)
Mar 3, 2026
30w ago
EFFECT
NEUTRAL ★ 3/10
$9.36 $9.77▲ +4.38%▲ +4.86%$8.44 (−9.83%)
Showing 10 of 10

US Market Status

Market Open — Closes in 51m

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