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Insider Buy ·Filed Oct 26, 2026

PRTA

PROTHENA CORP PUBLIC LTD CO
BULLISH
Impact 5/10
Horizonweeks Processed1d 4h ago SEC0001045463-26-000022
Insider cluster: 1 insiders, $819K total
Actionable Insight ▲ Bullish

The cluster of open-market purchases by a 10% owner at current levels signals strong insider conviction. Monitor for any upcoming corporate events (pipeline updates, regulatory milestones) that may have prompted the buying, and watch for additional insider filings or institutional accumulation.

DirectionBullish
Confidencehigh
Horizonweeks

Price Chart

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Executive Summary

Prothena director and 10% owner William Scully purchased $819K in open-market shares on October 22, 2026, at $8.19 per share, outside a 10b5-1 plan. This follows his $404K purchase on October 23, bringing his two-day total to $1.22M. The insider buying cluster is significant relative to the company's $424M market cap (0.29% combined) and signals conviction from a major shareholder.

Key Financial Metrics

Direction
buying
Total Value
$819.0K
Insiders
1

Key Facts

  • William Scully, a 10% owner, purchased 100,000 shares at $8.19 for $819K on October 22, 2026.
  • The purchase was an open-market transaction (Form 4 code P) with no 10b5-1 plan.
  • Scully also bought 50,000 shares at $8.07 for $404K on October 23, 2026, for a two-day total of $1.22M.
  • The combined $1.22M represents 0.29% of Prothena's $424M market cap.
  • Recent insider activity (30 days) shows 9 buys totaling $7.1M, indicating sustained insider conviction.
  • Institutional holders include Fidelity ($70M), Rubric Capital Management ($49M), and BlackRock ($48M).

Financial Impact

Insider purchase of $819K (0.19% of market cap) by a 10% owner, with no 10b5-1 plan.

insider ownershipmarket sentiment

Risk Factors

  • Insider buying does not guarantee near-term stock performance; the stock may still face clinical or regulatory risks.
  • The company is a biotech with no approved products, making it inherently volatile and dependent on pipeline success.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
67% bullish (12 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
INSIDER-BUY Data (Synthetic)0001045463-26-000022
15 reports for PRTA
Performance horizon
56% Hit rate @ T+1 5 of 9 directional calls Went positive at some point 6 of 9 best @ T+60▲ +14.11%Jun 12, 2026
Filters
Rows
Reports for PRTA — sortable, filterable
TypeNow
Oct 26, 2026
1d ago
Insider Buy
BULLISH ★ 5/10
$8.40awaiting T+1—$8.40 (−0.00%)
Oct 15, 2026
12d ago
Insider Buy
BULLISH ★ 5/10
$8.35 $8.48▲ +1.56%▲ +1.13%$8.40 (+0.60%)
Sep 30, 2026
27d ago
Insider Buy
BULLISH ★ 5/10
$8.54 $8.36▼ −2.11%▼ −2.85%$8.40 (−1.64%)
Sep 29, 2026
28d ago
Insider Buy
BULLISH ★ 5/10
$8.38 $8.54▲ +1.91%▲ +1.73%$8.40 (+0.24%)
Sep 21, 2026
5w ago
Insider Buy
BULLISH ★ 6/10
$8.99 $8.68▼ −3.45%▼ −2.73%$8.40 (−6.56%)
Sep 3, 2026
7w ago
Insider Buy
NEUTRAL ★ 3/10
$9.82 $9.54▼ −2.85%▼ −2.30%$8.40 (−14.46%)
Aug 21, 2026
9w ago
Insider Buy
BULLISH ★ 4/10
$9.45 $9.39▼ −0.63%▼ −0.34%$8.40 (−11.11%)
Aug 10, 2026
11w ago
Insider Buy
BULLISH ★ 5/10
$9.12 $9.22▲ +1.10%▲ +1.42%$8.40 (−7.89%)
Jul 30, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$8.12 $8.33▲ +2.59%▲ +1.16%$8.40 (+3.45%)
Jun 18, 2026
18w ago
Insider Buy
BULLISH ★ 5/10
$8.93 $9.15▲ +2.46%▲ +2.78%$8.40 (−5.94%)
Showing 10 of 15

US Market Status

Market Closed — Opens Thu (13h 3m)

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Report published Oct 26, 2026