Vanguard's reduction below 5% removes a major passive holder from the 5%+ ownership list. Monitor for further institutional selling and any impact on stock liquidity.
Price Chart
Executive Summary
Vanguard Portfolio Management LLC filed an amended Schedule 13G for Krystal Biotech, reporting beneficial ownership of 1,312,431 shares (4.43% of common stock) as of September 30, 2026. This is a decrease from the prior filing three days ago, which reported 3,427,645 shares (11.6%), indicating a significant reduction in Vanguard's stake below the 5% threshold.
Key Financial Metrics
Key Facts
- Vanguard Portfolio Management LLC filed an amended Schedule 13G for Krystal Biotech, Inc.
- Beneficial ownership reported as 1,312,431 shares (4.43% of common stock) as of September 30, 2026.
- This is a decrease from the prior filing on October 27, 2026, which reported 3,427,645 shares (11.6%).
- The stake has fallen below the 5% threshold, indicating a significant reduction in Vanguard's position.
Financial Impact
Vanguard reduced its stake from 11.6% to 4.43%, a reduction of approximately 2,115,214 shares. At the current market cap of $9.5B, this represents a significant sell-down.
Risk Factors
- Large institutional holder reducing stake may signal reduced confidence or a portfolio rebalancing.
- Potential for further selling pressure if other institutions follow suit.
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 3 SEC documents filed with EDGAR.
| Document | Accession Number |
|---|---|
| SC 13G/A Filing (Primary) | 0002100121-26-001077 |
| Document: 0002100121-26-001077-index.html | 0002100121-26-001077 |
| Document: 0002100121-26-001077.txt | 0002100121-26-001077 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Oct 30, 2026 2d ago | SC 13G/A | $328.98 | awaiting T+20 | awaiting T+20 | $332.29 (−1.01%) |
Oct 27, 2026 5d ago | Institutional Cluster | $321.42 | awaiting T+20 | awaiting T+20 | $332.29 (+3.38%) |
Oct 27, 2026 5d ago | SC 13G/A | $321.42 | awaiting T+20 | awaiting T+20 | $332.29 (+3.38%) |
Oct 22, 2026 10d ago | Press Release | $320.13 | awaiting T+20 | awaiting T+20 | $332.29 (+3.80%) |
Oct 21, 2026 11d ago | Institutional Cluster | $320.13 | awaiting T+20 | awaiting T+20 | $332.29 (+3.80%) |
Oct 15, 2026 17d ago | 8-K | $330.00 | awaiting T+20 | awaiting T+20 | $332.29 (+0.69%) |
Sep 4, 2026 8w ago | Insider Cluster | $351.26 $326.81 | ▲ +6.96% | ▲ +8.67% | $332.29 (+5.40%) |
Aug 14, 2026 11w ago | 144 | $335.73 $336.68 | ▲ +0.28% | ▲ +2.26% | $332.29 (−1.02%) |
Aug 3, 2026 12w ago | 8-K | $312.57 $359.36 | ▲ +14.97% | ▲ +13.73% | $332.29 (+6.31%) |
Jul 23, 2026 14w ago | Press Release | $335.19 $346.58 | ▲ +3.40% | ▼ −0.23% | $332.29 (−0.87%) |
US Market Status
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