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Institutional Cluster ·Filed Oct 21, 2026

KRYS

Krystal Biotech, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed6d 9h ago
Institutional cluster: 4 buyers, 1 sellers (bullish)
Actionable Insight • Neutral

The cluster is small in dollar terms and dominated by routine asset-manager rebalancing. No activist or event-driven fund participation. Monitor next 13F for continuation or reversal of this accumulation pattern.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+1d
KRYS ▼ -2.70% at T+1d
NEUTRAL call -2.70% · α vs SPY -2.17% · entry $320.13 → $311.50
Next anchor: T+5d in 7h
Entry = T+0 close
Oct 21, 2026
via day close
T+1d
-2.70%
call -2.70% · α -2.17%
$311.50
settled 6d ago
T+5d
Pending
in 7h
T+20d
Pending
in 21d
T+60d
Pending
in 3mo

Executive Summary

Four institutional asset managers increased their KRYS positions in Q3 2026, led by Congress Asset Management adding $3.1M to bring its stake to $18.0M. One small seller trimmed $151K. The net $3.6M buying is modest relative to KRYS's market cap, and all participants are passive-oriented asset managers, not activist or event-driven funds.

Key Financial Metrics

Direction
accumulating
Buy Value
$20.2M
Sell Value
$299.0K
Net Flow
$3.6M

Institutional Positions

Net institutional flow: $3.6M

▲ Buyers (4)

InstitutionActionChangePosition ValueValue Δ
Congress Asset ManagementADD+34.8%$18.0M$3.1M
Wealth Enhancement Advisory ServicesDOUBLED+104.9%$437.0K$199.0K
AssetmarkADD+40.1%$1.7M$352.0K

▼ Sellers (1)

InstitutionActionChangePrev ValueValue Δ
Nisa Investment AdvisorsTRIM-25.8%$450.0K-$151.0K

Key Facts

  • 4 buyers added net $3.6M; 1 seller trimmed $151K
  • Congress Asset Management added $3.1M (34.8% increase) to a $18.0M position
  • Wealth Enhancement Advisory Services doubled its position (+$199K)
  • All participants are asset managers, not hedge funds or activists
  • 13F data is 45+ days stale; positions may have been unwound

Financial Impact

Net institutional buying of $3.6M across 4 funds, with Congress Asset Management accounting for $3.1M of the total. One seller reduced by $151K.

institutional ownership

Risk Factors

  • 13F data is stale (45+ day lag); positions may have been reversed
  • All buyers are passive-oriented asset managers — signal is weak
  • No hedge fund or activist involvement to suggest a catalyst thesis

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-KRYS-2026-Q3
15 reports for KRYS
Performance horizon
100% Hit rate @ T+20 3 of 3 directional calls Went positive at some point 3 of 4 best @ T+60▲ +26.60%May 4, 2026
Filters
Rows
Reports for KRYS — sortable, filterable
TypeNow
Oct 27, 2026
today
Institutional Cluster
BULLISH ★ 4/10
$311.52awaiting T+20——
Oct 27, 2026
today
SC 13G/A
NEUTRAL ★ 3/10
$311.52awaiting T+20——
Oct 22, 2026
5d ago
Press Release
NEUTRAL ★ 1/10
$320.13awaiting T+20——
Oct 21, 2026
6d ago
Institutional Cluster
NEUTRAL ★ 3/10
$320.13awaiting T+20——
Oct 15, 2026
12d ago
8-K
BULLISH ★ 6/10
$330.00awaiting T+20——
Sep 4, 2026
7w ago
Insider Cluster
BEARISH ★ 5/10
$351.26 $326.81▲ +6.96%▲ +8.67%—
Aug 14, 2026
10w ago
144
NEUTRAL ★ 2/10
$335.73 $336.68▲ +0.28%▲ +2.26%—
Aug 3, 2026
12w ago
8-K
BULLISH ★ 6/10
$312.57 $359.36▲ +14.97%▲ +13.73%—
Jul 23, 2026
13w ago
Press Release
NEUTRAL ★ 1/10
$335.19 $346.58▲ +3.40%▼ −0.23%—
Jun 5, 2026
20w ago
Insider Cluster
NEUTRAL ★ 2/10
$301.76 $374.68▲ +24.16%▲ +22.53%—
Showing 10 of 15

US Market Status

Market Closed — Opens in 8h 11m

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Report published Oct 21, 2026