The cluster is small and stale, with only one meaningful active manager move (Assenagon). The lack of insider buying and the 45-day lag reduce signal reliability. Monitor the Q4 2026 13F for whether these positions were maintained or sold after the stock offering and Phase 3 readout.
How similar events traded
Executive Summary
Four institutional investors increased their Disc Medicine positions in Q3 2026, led by Assenagon Asset Management which more than doubled its stake to $73.3M. The cluster follows the company's positive Phase 3 APOLLO bitopertin data and a $450M public offering, but the total net buying of $45.8M is modest relative to the $3.7B market cap and the 13F data is 45+ days stale.
Key Financial Metrics
Institutional Positions
Net institutional flow: $45.8M
▲ Buyers (4)
| Institution | Action | Change | Position Value | Value Δ |
|---|---|---|---|---|
| Assenagon Asset Management | DOUBLED | +191.4% | $73.3M | $45.2M |
| Alps Advisors | ADD | +31.9% | $3.3M | $508.0K |
| Creative Planning | ADD | +40.4% | $575.0K | $117.0K |
| Assetmark | ADD | +33.3% | $1.0K | $169.00 |
Key Facts
- 4 institutional buyers added $45.8M net in Q3 2026, with zero sellers in the cluster
- Assenagon Asset Management doubled its stake, adding $45.2M to reach $73.3M
- The cluster follows positive Phase 3 APOLLO data for bitopertin (Oct 19) and a $450M public offering (Oct 21-22)
- No open-market insider buying corroborates the institutional accumulation (confluence score 15/100)
- 13F data is at least 45 days stale; positions may have been unwound since quarter-end
Financial Impact
4 institutions accumulated $45.8M net in new positions, with Assenagon alone adding $45.2M
Risk Factors
- 13F data is 45+ days stale; positions may have been reduced or exited since September 30
- No insider buying corroboration weakens conviction signal
- Cluster dominated by one fund (Assenagon at 95% of net buying); not broad-based conviction
- Stock offering in October may have altered institutional positioning post-quarter-end
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 1 institutional 13F filing from SEC EDGAR.
| Document | Accession Number |
|---|---|
| INST-CLUSTER Data (Synthetic) | inst-cluster-IRON-2026-Q3 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Nov 4, 2026 today | Press Release | $82.49 | awaiting T+20 | awaiting T+20 | No price |
Nov 3, 2026 1d ago | Institutional Cluster | $79.41 | awaiting T+20 | awaiting T+20 | No price |
Oct 26, 2026 8d ago | SC 13D/A | $79.90 | awaiting T+20 | awaiting T+20 | No price |
Oct 22, 2026 12d ago | 8-K | $74.51 | awaiting T+20 | awaiting T+20 | No price |
Oct 21, 2026 13d ago | 424B5 | $75.03 | awaiting T+20 | awaiting T+20 | No price |
Oct 21, 2026 13d ago | 144 | $75.03 | awaiting T+20 | awaiting T+20 | No price |
Oct 21, 2026 13d ago | 144 | $75.03 | awaiting T+20 | awaiting T+20 | No price |
Oct 21, 2026 13d ago | 144 | $75.03 | awaiting T+20 | awaiting T+20 | No price |
Oct 20, 2026 14d ago | 144 | $76.00 | awaiting T+20 | awaiting T+20 | No price |
Oct 20, 2026 14d ago | 144 | $76.00 | awaiting T+20 | awaiting T+20 | No price |
US Market Status
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