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Insider Cluster (4 insiders) ·Filed Jun 30, 2026

IONS

IONIS PHARMACEUTICALS INC
NEUTRAL
Impact 2/10
Horizonimmediate Processed3mo ago
Insider cluster: 4 insiders, $7.2M total
Actionable Insight • Neutral

The insider selling is routine and immaterial in size. No immediate trading signal. Monitor for any upcoming pipeline catalysts or earnings, but this cluster alone does not warrant action.

DirectionNeutral
Confidencehigh
Horizonimmediate
Final — all horizons settled through T+60d
IONS ▼ -44.68% at T+60d
NEUTRAL call -44.68% · α vs SPY -47.55% · entry $79.19 → $43.81
Entry = T+0 close
Jun 30, 2026
via day close
T+1d
+3.30%
call +3.30% · α +3.43%
$81.80
settled 4mo ago
T+5d
+9.02%
call +9.02% · α +8.75%
$86.33
settled 4mo ago
T+20d
-31.76%
call -31.76% · α -29.57%
$54.04
settled 3mo ago
T+60d
-44.68%
call -44.68% · α -47.55%
$43.81
settled 5w ago

Price Chart

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Executive Summary

Four IONIS executives, including CEO Brett Monia, sold a total of $7.22M in open-market shares over a three-day window. The sales represent only 0.054% of the company's $13.3B market cap, making them trivial in scale and routine in nature.

Key Financial Metrics

Direction
selling
Total Value
$7.2M
Insiders
4

Key Facts

  • CEO Brett Monia sold $4.03M worth of shares on June 26, 2026, plus additional sales on June 24-25 totaling ~$2.8M.
  • Total insider open-market sales of $7.22M represent just 0.054% of IONS' $13.3B market cap.
  • All sales were preceded by option exercises at zero or low strike prices, consistent with tax-motivated diversification.
  • No insider purchases were reported in the cluster.

Financial Impact

Insider sales of $7.22M are negligible relative to $13.3B market cap (0.054%).

Risk Factors

  • Insider selling could be misinterpreted as bearish, but the magnitude is too small to be informative.
  • CEO selling a large absolute dollar amount may attract attention, but it is proportional to his holdings and likely part of a planned 10b5-1 program.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
82% bullish (33 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-IONS-1782856154465
24 reports for IONS
Performance horizon
57% Hit rate @ T+20 4 of 7 directional calls Went positive at some point 7 of 9 best @ T+60▲ +32.25%Jul 9, 2026
Filters
Rows
Reports for IONS — sortable, filterable
TypeNow
Oct 23, 2026
3d ago
8-K
BULLISH ★ 7/10
$42.93awaiting T+20—$43.63 (+1.63%)
Oct 21, 2026
5d ago
8-K
BULLISH ★ 7/10
$43.91awaiting T+20—$43.63 (−0.64%)
Oct 21, 2026
5d ago
Institutional Cluster
MIXED ★ 3/10
$43.91awaiting T+20—$43.63 (−0.64%)
Sep 23, 2026
4w ago
8-K
BULLISH ★ 7/10
$43.93 $44.27▲ +0.77%▲ +0.09%$43.63 (−0.68%)
Sep 4, 2026
7w ago
8-K
BEARISH ★ 7/10
$56.71 $44.00▲ +22.41%▲ +24.13%$43.63 (+23.06%)
Sep 4, 2026
7w ago
8-K
BULLISH ★ 7/10
$58.09 $43.50▼ −25.12%▼ −25.72%$43.63 (−24.89%)
Jul 31, 2026
12w ago
Insider Buy
NEUTRAL ★ 4/10
$54.49 $60.36▲ +10.77%▲ +9.53%$43.63 (−19.93%)
Jul 29, 2026
12w ago
8-K
MIXED ★ 6/10
$54.04 $63.36▲ +17.25%▲ +12.23%$43.63 (−19.26%)
Jul 9, 2026
15w ago
8-K
NEUTRAL ★ 2/10
$58.25 $56.56▼ −2.90%▼ −5.33%$43.63 (−25.10%)
Jul 9, 2026
15w ago
Insider Cluster
NEUTRAL ★ 2/10
$58.25 $56.56▼ −2.90%▼ −5.33%$43.63 (−25.10%)
Showing 10 of 24

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Report published Jun 30, 2026