144 ·Filed May 27, 2026

ANAB

ANAPTYSBIO, INC
BEARISH
Impact 6/10
Horizondays Processed4mo ago SEC0001950047-26-005168
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

The CEO's sustained selling pattern (55K+ shares in 12 days) is a bearish signal, especially given the company's $1.7B market cap and 89% analyst buy rating. Monitor for any negative news or guidance changes in the next 10-Q. The 144 is an intent to sell, but the pattern suggests the insider is actively reducing exposure.

DirectionBearish
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
ANAB ▲ +1.26% at T+60d
SHORT call ✗ call lost -1.26% · α vs SPY +0.47% · entry $57.02 → $57.74
Entry anchored
May 27, 2026
via day open
T+1d
-2.37%
call +2.37% · α +2.61%
$55.67
settled 4mo ago
T+5d
-9.38%
call +9.38% · α +9.70%
$51.67
settled 4mo ago
T+20d
+10.75%
call -10.75% · α -13.90%
$63.15
settled 3mo ago
T+60d
+1.26%
call -1.26% · α +0.47%
$57.74
settled 6w ago

Price Chart

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Executive Summary

CEO Dennis Mulroy filed a Form 144 notice to sell 10,000 shares of AnaptysBio common stock, valued at approximately $585,006 based on the filing date price. This follows a series of recent sales by Mulroy totaling over 55,000 shares in the past two weeks, representing a significant insider selling pattern ahead of potential catalysts.

Key Facts

  • CEO Dennis Mulroy filed Form 144 on 2026-05-27 to sell 10,000 shares at ~$585,006.
  • Mulroy has sold 55,467 shares in the prior 12 days (5/15-5/26) for ~$3.33M total.
  • The proposed sale is via Morgan Stanley Smith Barney, with shares acquired from stock option exercise on 5/27/2026.
  • No lock-up expiration or earnings catalyst is indicated in the filing; the sales appear discretionary.

Financial Impact

CEO selling ~$585K in proposed sale, with $3.33M in recent prior sales over 12 days; total insider selling of ~$3.9M in under two weeks.

insider selling volumeCEO holdings reduction

Risk Factors

  • CEO selling may signal lack of confidence in near-term prospects or upcoming negative catalyst.
  • Continued insider selling could pressure stock price and erode investor sentiment.
  • No offsetting insider buying or positive corporate events in the filing to counterbalance the selling.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
89% bullish (18 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-005168
Document: 0001950047-26-005168-index.html0001950047-26-005168
Document: 0001950047-26-005168.txt0001950047-26-005168
24 reports for ANAB
Performance horizon
65% Hit rate 11 of 17 directional calls best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
TypeNow
Aug 12, 2026
7w ago
Institutional Cluster
BULLISH ★ 5/10
$56.02 $53.87▼ −3.84%▼ −2.09%$48.77 (−12.94%)
Jun 29, 2026
13w ago
144
BEARISH ★ 6/10
$67.50 $53.61▲ +20.58%▲ +19.55%$48.77 (+27.75%)
Jun 29, 2026
13w ago
DEFA14A
NEUTRAL ★ 2/10
$67.50 $53.61▼ −20.58%▼ −19.55%$48.77 (−27.75%)
Jun 26, 2026
13w ago
144
BEARISH ★ 6/10
$65.97 $54.15▲ +17.92%▲ +17.64%$48.77 (+26.07%)
Jun 22, 2026
14w ago
8-K
NEUTRAL ★ 2/10
$59.43 $50.29▼ −15.38%▼ −16.54%$48.77 (−17.94%)
Jun 17, 2026
15w ago
144
BEARISH ★ 5/10
$57.51 $54.15▲ +5.84%▲ +6.38%$48.77 (+15.20%)
Jun 15, 2026
15w ago
144
BEARISH ★ 6/10
$57.61 $62.51▼ −8.51%▼ −8.31%$48.77 (+15.34%)
Jun 11, 2026
16w ago
144
BEARISH ★ 6/10
$56.07 $66.39▼ −18.41%▼ −16.63%$48.77 (+13.02%)
Jun 10, 2026
16w ago
144
BEARISH ★ 5/10
$54.24 $66.59▼ −22.77%▼ −20.88%$48.77 (+10.08%)
Jun 8, 2026
16w ago
144
BEARISH ★ 5/10
$51.63 $67.33▼ −30.40%▼ −28.95%$48.77 (+5.54%)
Showing 10 of 24

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