SecBot SecBot
PRESS-RELEASE ·Filed Sep 21, 2026

ANAB

AnaptysBio, Inc.
NEUTRAL
Impact 5/10
Horizonweeks Processed1mo ago WireGlobeNewswire
Press release · Earnings
Actionable Insight • Neutral

The EPS miss is largely non-operational due to the First Tracks separation and one-time tax benefit; focus on Jemperli royalty growth trajectory (26% YoY) and upcoming binary catalysts: FDA decisions on Jemperli (Feb 2027) and Quimilza (Dec 2026), plus the GSK litigation judgment (Q4 2026/Q1 2027) which could return Jemperli rights to Anaptys. Monitor the Oct 20 post-trial hearing for litigation signals.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+20d
ANAB ▼ -15.75% at T+20d
NEUTRAL call -15.75% · α vs SPY -15.19% · entry $53.92 → $45.43
Next anchor: T+60d in 7w
Latest observation: T+23 -6.70% FF3 residual α
Entry = T+0 close
Sep 21, 2026
via day close
T+1d
-5.84%
call -5.84% · α -5.12%
$50.77
settled 5w ago
T+5d
-6.58%
call -6.58% · α -5.40%
$50.37
settled 28d ago
T+20d
-15.75%
call -15.75% · α -15.19%
$45.43
settled 7d ago
T+60d
Pending
in 7w

Price Chart

Loading chart...

Executive Summary

AnaptysBio reported Q2 2026 EPS of $0.07, a 50.5% miss vs consensus of $0.14, though collaboration revenue of $27.5M beat the $20.1M estimate. The company highlighted strong Jemperli royalty growth (26% YoY) and upcoming catalysts: FDA PDUFA for Jemperli in rectal cancer (Feb 2027) and Quimilza in GPP (Dec 2026), plus a pending litigation judgment against GSK/Tesaro expected in Q4 2026/Q1 2027. The EPS miss is largely mechanical due to the separation of First Tracks Biotherapeutics and a one-time $181.5M tax benefit that inflated GAAP net income, making the headline EPS unreliable for operational assessment.

Key Financial Metrics

EPS
$0.07
est $0.14 · -50.0%
Revenue
$27.5M
est $20.1M · +36.8% · +23.5% YoY
Rating
miss

Key Facts

  • Q2 2026 EPS $0.07 vs consensus $0.14 (50.5% miss)
  • Q2 2026 collaboration revenue $27.5M vs consensus $20.1M (36.8% beat)
  • Jemperli global net sales $331M for Q2 2026, 26% YoY growth
  • Cash, equivalents and investments $164.1M as of June 30, 2026, down from $211.6M at Dec 31, 2025
  • Separation of First Tracks Biotherapeutics completed April 20, 2026; fiscal year changed to June 30
  • FDA PDUFA action date Feb 2027 for Jemperli in untreated dMMR/MSI-H rectal cancer; eligible for expedited review
  • FDA PDUFA action date Dec 12, 2026 for Quimilza in generalized pustular psoriasis
  • Litigation with GSK/Tesaro trial held July 2026; post-trial hearing Oct 20, 2026; judgment expected Q4 2026 or Q1 2027
  • Net income from continuing operations $177.3M for Q2 2026, including $181.5M tax benefit from valuation allowance release
  • $100M stock repurchase plan authorized; no shares repurchased as of June 30, 2026

Financial Impact

EPS miss of $0.07 vs $0.14 consensus (-50.5%) but revenue beat of $27.5M vs $20.1M (+36.8%); GAAP net income inflated by $181.5M non-cash tax benefit

epsrevenuecashroyalties

Risk Factors

  • GSK/Tesaro litigation outcome uncertain; loss could impair Jemperli royalty stream
  • Cash burn continues ($47.5M decrease in H1 2026) with no repurchases under $100M buyback plan
  • FDA decisions on Jemperli and Quimilza are binary and subject to delay or rejection
  • EPS volatility from discontinued operations and one-time tax items obscures underlying performance

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3365866
25 reports for ANAB
Performance horizon
50% Hit rate @ T+1 9 of 18 directional calls Went positive at some point 12 of 18 best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
TypeNow
Sep 21, 2026
4w ago
Press Release
NEUTRAL ★ 5/10
$53.92 $50.77▼ −5.84%▼ −5.12%$49.07 (−8.99%)
Aug 12, 2026
10w ago
Institutional Cluster
BULLISH ★ 5/10
$56.02 $58.47▲ +4.37%▲ +4.57%$49.07 (−12.41%)
Jun 29, 2026
16w ago
144
BEARISH ★ 6/10
$67.50 $65.43▲ +3.07%▲ +2.93%$49.07 (+27.30%)
Jun 29, 2026
16w ago
DEFA14A
NEUTRAL ★ 2/10
$67.50 $65.43▼ −3.07%▼ −2.93%$49.07 (−27.30%)
Jun 26, 2026
17w ago
144
BEARISH ★ 6/10
$65.97 $67.50▼ −2.32%▼ −1.54%$49.07 (+25.62%)
Jun 22, 2026
17w ago
8-K
NEUTRAL ★ 2/10
$59.43 $58.48▼ −1.60%▼ −1.55%$49.07 (−17.43%)
Jun 17, 2026
18w ago
144
BEARISH ★ 5/10
$57.51 $59.99▼ −4.31%▼ −4.63%$49.07 (+14.68%)
Jun 15, 2026
18w ago
144
BEARISH ★ 6/10
$57.61 $56.77▲ +1.46%▲ +0.21%$49.07 (+14.82%)
Jun 11, 2026
19w ago
144
BEARISH ★ 6/10
$56.07 $59.51▼ −6.14%▼ −4.37%$49.07 (+12.48%)
Jun 10, 2026
19w ago
144
BEARISH ★ 5/10
$54.24 $56.07▼ −3.37%▼ −2.83%$49.07 (+9.53%)
Showing 10 of 25

US Market Status

Market Open — Closes in 5h 41m

Subscribe to SecBot

Get Real-Time SEC Filing Intelligence

Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.

Create a free account Live analysis, Telegram alerts, watchlists and the MCP server for subscribers
Report published Sep 21, 2026