144 ·Filed May 22, 2026

ANAB

ANAPTYSBIO, INC
BEARISH
Impact 5/10
Horizondays Processed3mo ago SEC0001950047-26-004947
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

This is the fourth insider sale filing from the same officer within one week, signaling a routine option-exercise/cash-out cycle but at an elevated frequency. For a $1.5B biotech with no disclosed near-term catalyst, the concentrated selling is a modest negative signal. Historical reports on ANAB have shown poor T+20 performance (avg -9.4%), suggesting caution. Monitor for additional Form 4 filings or a material change in corporate outlook that could explain the selling.

DirectionBearish
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
ANAB ▲ +2.58% at T+60d
SHORT call ✗ call lost -2.58% · α vs SPY +0.15% · entry $57.77 → $59.26
Entry anchored
May 22, 03:59 PM ET
via exchange tick
T+1d
-0.14%
call +0.14% · α +0.15%
$57.69
settled 4mo ago
T+5d
-11.27%
call +11.27% · α +12.48%
$51.26
settled 4mo ago
T+20d
+1.92%
call -1.92% · α -3.87%
$58.88
settled 3mo ago
T+60d
+2.58%
call -2.58% · α +0.15%
$59.26
settled 6w ago

Price Chart

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Executive Summary

Dennis Mulroy, an officer of AnaptysBio, filed a Form 144 notice of intent to sell 10,000 shares of common stock, valued at approximately $593,008 based on the filing date price. This follows three prior sales in the same week totaling 35,467 shares for ~$2.16M, indicating a concentrated selling pattern by an insider.

Key Facts

  • Form 144 filed on 2026-05-22 by officer Dennis Mulroy
  • Proposed sale of 10,000 shares of common stock
  • Estimated value: ~$593,008 at market price on filing date
  • Shares acquired via stock option exercise on 05/22/2026 for cash
  • Three prior open-market sales by Mulroy in the preceding week: 15,467 shares on 05/21 ($928k), 10,000 on 05/19 ($599k), 10,000 on 05/15 ($633k)
  • Cumulative insider sales by Mulroy in the past week: ~45,467 shares for ~$2.75M

Financial Impact

Proposed additional sale of ~$593k; combined week of insider selling totals ~$2.75M against a $1.5B market cap

dilutioninsider ownership

Risk Factors

  • Insider selling may indicate lack of confidence in near-term share appreciation
  • Historical T+20 performance on ANAB filings has been negative across several prior reads
  • Biotech sector volatility could amplify any negative sentiment from insider sales

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
94% bullish (17 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-004947
Document: 0001950047-26-004947-index.html0001950047-26-004947
Document: 0001950047-26-004947.txt0001950047-26-004947
24 reports for ANAB
Performance horizon
65% Hit rate 11 of 17 directional calls best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
TypeNow
Aug 12, 2026
7w ago
Institutional Cluster
BULLISH ★ 5/10
$56.02 $53.87▼ −3.84%▼ −2.09%$48.53 (−13.37%)
Jun 29, 2026
13w ago
144
BEARISH ★ 6/10
$67.50 $53.61▲ +20.58%▲ +19.55%$48.53 (+28.10%)
Jun 29, 2026
13w ago
DEFA14A
NEUTRAL ★ 2/10
$67.50 $53.61▼ −20.58%▼ −19.55%$48.53 (−28.10%)
Jun 26, 2026
14w ago
144
BEARISH ★ 6/10
$65.97 $54.15▲ +17.92%▲ +17.64%$48.53 (+26.44%)
Jun 22, 2026
14w ago
8-K
NEUTRAL ★ 2/10
$59.43 $50.29▼ −15.38%▼ −16.54%$48.53 (−18.34%)
Jun 17, 2026
15w ago
144
BEARISH ★ 5/10
$57.51 $54.15▲ +5.84%▲ +6.38%$48.53 (+15.61%)
Jun 15, 2026
15w ago
144
BEARISH ★ 6/10
$57.61 $62.51▼ −8.51%▼ −8.31%$48.53 (+15.76%)
Jun 11, 2026
16w ago
144
BEARISH ★ 6/10
$56.07 $66.39▼ −18.41%▼ −16.63%$48.53 (+13.45%)
Jun 10, 2026
16w ago
144
BEARISH ★ 5/10
$54.24 $66.59▼ −22.77%▼ −20.88%$48.53 (+10.53%)
Jun 8, 2026
16w ago
144
BEARISH ★ 5/10
$51.63 $67.33▼ −30.40%▼ −28.95%$48.53 (+6.00%)
Showing 10 of 24

US Market Status

Market Closed — Opens Mon (38h 32m)

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