144 ·Filed Jun 3, 2026

ANAB

ANAPTYSBIO, INC
BEARISH
Impact 5/10
Horizondays Processed4mo ago SEC0001950047-26-005601
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

The CEO's persistent selling pattern (nearly daily for two weeks) is a bearish signal, especially given the stock's poor historical T+20 performance. Traders should monitor for any negative catalyst or guidance revision that may have prompted the selling. Consider reducing long exposure or hedging ahead of the next earnings or material event.

DirectionBearish
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
ANAB ▲ +8.92% at T+60d
SHORT call ✗ call lost -8.92% · α vs SPY -7.04% · entry $51.67 → $56.28
Entry anchored
Jun 3, 2026
via day open
T+1d
-2.52%
call +2.52% · α -0.08%
$50.37
settled 4mo ago
T+5d
+4.97%
call -4.97% · α -7.53%
$54.24
settled 4mo ago
T+20d
+22.74%
call -22.74% · α -24.11%
$63.42
settled 3mo ago
T+60d
+8.92%
call -8.92% · α -7.04%
$56.28
settled 5w ago

Price Chart

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Executive Summary

CEO Dennis Mulroy filed a Form 144 to sell 20,000 shares (~$1.0M at filing) via a stock option exercise, signaling intent to sell. This follows a heavy selling pattern: Mulroy has sold ~127,422 shares worth ~$7.5M over the prior two weeks (May 15–June 2), including 10,000–15,000 share blocks nearly every trading day. The persistent insider selling ahead of no disclosed positive catalyst is a bearish signal, especially given the stock's poor historical T+20 performance (33% win rate, -9.38% avg return) and the company's 94% analyst bullishness creating potential disappointment risk.

Key Facts

  • CEO Dennis Mulroy filed Form 144 to sell 20,000 shares via stock option exercise, with an estimated market value of ~$1,017,250.
  • Mulroy has sold ~127,422 shares worth ~$7.5M in the 15 trading days prior (May 15–June 2), including daily blocks of 10,000–15,000 shares.
  • The filing is an advance notice of intent to sell; the actual sale may or may not occur, but the pattern of persistent insider selling is notable.
  • No cross-filing context (earnings, M&A, or other material events) was provided to explain the selling.
  • Historical reports on ANAB show a 33% win rate at T+20 with an average return of -9.38%, suggesting the stock has underperformed following prior filings.

Financial Impact

CEO selling ~$1.0M in this notice, with ~$7.5M sold in the prior two weeks; total insider sales represent a small fraction of the $1.5B market cap but are concentrated and persistent.

insider sellingdilution

Risk Factors

  • CEO selling may signal lack of confidence in near-term prospects or upcoming negative news.
  • Heavy insider selling could pressure the stock price as the market interprets the pattern.
  • The stock's historical T+20 performance following filings has been poor (33% win rate, -9.38% avg return).

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
94% bullish (17 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-005601
Document: 0001950047-26-005601-index.html0001950047-26-005601
Document: 0001950047-26-005601.txt0001950047-26-005601
24 reports for ANAB
Performance horizon
65% Hit rate 11 of 17 directional calls best @ T+60▲ +41.26%Mar 3, 2026
Filters
Rows
Reports for ANAB — sortable, filterable
TypeNow
Aug 12, 2026
7w ago
Institutional Cluster
BULLISH ★ 5/10
$56.02 $53.87▼ −3.84%▼ −2.09%$48.53 (−13.37%)
Jun 29, 2026
13w ago
144
BEARISH ★ 6/10
$67.50 $53.61▲ +20.58%▲ +19.55%$48.53 (+28.10%)
Jun 29, 2026
13w ago
DEFA14A
NEUTRAL ★ 2/10
$67.50 $53.61▼ −20.58%▼ −19.55%$48.53 (−28.10%)
Jun 26, 2026
14w ago
144
BEARISH ★ 6/10
$65.97 $54.15▲ +17.92%▲ +17.64%$48.53 (+26.44%)
Jun 22, 2026
14w ago
8-K
NEUTRAL ★ 2/10
$59.43 $50.29▼ −15.38%▼ −16.54%$48.53 (−18.34%)
Jun 17, 2026
15w ago
144
BEARISH ★ 5/10
$57.51 $54.15▲ +5.84%▲ +6.38%$48.53 (+15.61%)
Jun 15, 2026
15w ago
144
BEARISH ★ 6/10
$57.61 $62.51▼ −8.51%▼ −8.31%$48.53 (+15.76%)
Jun 11, 2026
16w ago
144
BEARISH ★ 6/10
$56.07 $66.39▼ −18.41%▼ −16.63%$48.53 (+13.45%)
Jun 10, 2026
16w ago
144
BEARISH ★ 5/10
$54.24 $66.59▼ −22.77%▼ −20.88%$48.53 (+10.53%)
Jun 8, 2026
16w ago
144
BEARISH ★ 5/10
$51.63 $67.33▼ −30.40%▼ −28.95%$48.53 (+6.00%)
Showing 10 of 24

US Market Status

Market Closed — Opens Mon (64h 9m)

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