ANALYST-UPGRADE

AMGN

AMGEN INC
NEUTRAL
Impact 1/10
Processed5mo ago SECanalyst-AMGN-canaccor-20260421
Canaccord Genuity initiates coverage on AMGN at Hold
Actionable Insight • Neutral

Neutral initiation from a low-accuracy firm provides minimal new information. With earnings in 8 days and high short interest, price action will likely be driven by fundamentals, not this call. Avoid positioning based on this trigger.

DirectionNeutral
Final — all horizons settled through T+60d ⚠ clustered
AMGN ▲ +7.85% at T+60d
NEUTRAL call ✓ call won +7.85% · α vs SPY +1.23% · entry $344.52 → $371.58
Entry anchored
Apr 21, 11:59 AM ET
via exchange tick
T+1d
+0.36%
call +0.36% · α -0.66%
$345.77
settled 5mo ago
T+5d
-1.50%
call -1.50% · α -2.58%
$339.37
settled 5mo ago
T+20d
-5.84%
call -5.84% · α -10.76%
$324.39
settled 5mo ago
T+60d
+7.85%
call +7.85% · α +1.23%
$371.58
settled 3mo ago

Price Chart

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Executive Summary

Canaccord Genuity initiates Amgen (AMGN) at Hold with a $366 price target, implying 4.5% upside from $350.16. The firm's accuracy is below average at 47% (722/1538), and its call is below the consensus Buy rating (62% Buy/Hold). The mean price target is $352.03, with Canaccord’s $366 above median. AMGN reports earnings in 8 days. EPS estimates are stable, with slight downward revisions over 30 days. Institutional activity shows divergence: Renaissance Technologies trimmed, Two Sigma doubled. Short ratio is elevated at 57.4%. Bottom line: low-conviction initiation from a below-average firm ahead of earnings limits impact.

Impact Score

Base Score
0/7
LLM Adjustment
-1
Final Score
1/10

Consensus & Targets

Buy / Strong Buy
21 (49%)
Hold
19
Sell / Strong Sell
3
Total Analysts
29
Mean PT
$352.03
Median PT
$351.00
High PT
$432.00
Low PT
$200.00
Current Price
$350.16
Implied Upside
+0.5%

Of 29 analysts, 21 rate AMGN as Buy (72.4%), 19 Hold (65.5%), 2 Sell, and 1 Strong Sell. Note: totals exceed 100% due to rounding. The consensus leans Buy, with a clear majority favoring positive sentiment. Canaccord’s Hold rating is below consensus and aligns with only 65.5% of analysts.

The consensus mean price target is $352.03, median $351, range $200–$432. At $350.16, shares imply 0.5% upside to the mean. Canaccord’s $366 target is 4.0% above the mean and 4.3% above the median, positioning it above average but not outlier. Piper Sandler’s $432 target remains the high.

Recent Analyst Activity

DateFirmActionRatingPrice Target
2026-04-21Canaccord GenuityinitiateHold$366.00
2026-04-13UBSmaintainBuy$400.00
2026-04-10Morgan StanleymaintainEqual-Weight$326.00
2026-04-09GuggenheimmaintainNeutral$351.00
2026-04-08Cantor FitzgeraldreiterateNeutral$350.00
2026-03-10JefferiesinitiateHold$350.00
2026-02-20BarclaysinitiateEqual-Weight$350.00
2026-02-19Wells FargomaintainEqual-Weight$375.00
2026-02-18Piper SandlermaintainOverweight$432.00
2026-02-12Freedom BrokerdowngradeHold$375.00

Over the past 30 days, there has been 1 upgrade and 0 downgrades. EPS revisions show modest downward pressure: for current year (0y), 4 revisions up vs 6 down; for +1y, 8 up vs 6 down. Near-term estimates (0q, +1q) show slight trimming, indicating softening sentiment despite stable current estimates.

Firm Track Record — Canaccord Genuity

Canaccord Genuity accuracy: 47% on 1538 calls | avg return: 3%

Industry benchmark: mean 51% ± 11%. Top tier: ≥61% (mean + 1σ). Based on 13 firms with ≥5 scored calls.

FirmAccuracyCallsAvg Returnvs Average
BMO Capital100%3/37.1%top tier
Truist Securities100%3/34.8%top tier
Mizuho100%2/24%top tier
RBC Capital88%7/84.9%top tier
Morgan Stanley86%6/76.9%top tier
UBS86%6/77%top tier
B of A Securities80%4/51%top tier
Wells Fargo75%3/411.9%top tier
Piper Sandler67%4/68%top tier
TD Cowen67%2/36.4%top tier

Canaccord Genuity has a 47% accuracy rate (722 correct out of 1538 rated stocks), below the average firm. Their average return on rated stocks is +3%. Among 13 firms covering AMGN, 8 are top-tier (80–100% accuracy), including Morgan Stanley (86%, 6.9% avg return) and UBS (86%, 7%). Canaccord ranks near the bottom in reliability.

Earnings Estimates

Next earnings: Apr 29, 2026

PeriodEPS Est.EPS RangeRevenueRevisions (7d)
0q$4.79$4.17 — $6.15$8.6B↑6 ↓0
+1q$5.75$4.65 — $6.23$9.5B↑3 ↓0
0y$22.35$21.58 — $23.18$37.8B↑5 ↓0
+1y$23.29$20.80 — $25.04$38.7B↑5 ↓0

Cross-Platform Signals

Congressional
David Taylor (republican) — sell $1,001 - $15,000
Institutional
NORGES BANK — new
Institutional
RENAISSANCE TECHNOLOGIES LLC — exit (-100%)
Institutional
TWO SIGMA INVESTMENTS, LP — doubled (835.1%)
Short Interest
Short: 307,989 | Exempt: 4,018 | TRF Vol: 536,629 | Short Ratio: 57.4% | Off-exchange volume (dark pool + OTC)

Institutional activity is mixed: Two Sigma increased position by 835.1%, while Renaissance Technologies exited and then trimmed further. Norges Bank entered and exited. No insider trades reported. Congressional trade: Rep. David Taylor (R) sold $1k–$15k on Feb 26. Short interest is extremely high at 57.4% of float, suggesting elevated bearish positioning ahead of earnings. Analyst sentiment (bullish) diverges from short and some institutional signals (bearish).

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

Report based on filing metadata.

16 reports for AMGN
Performance horizon
83% Hit rate 5 of 6 directional calls best @ T+60▲ +29.13%Jun 3, 2026
Filters
Rows
Reports for AMGN — sortable, filterable
TypeNow
Sep 10, 2026
22d ago
ANALYST-DOWNGRADE
BEARISH ★ 4/10
$382.47 $379.78▲ +0.70%▲ +0.20%$403.04 (−5.38%)
Sep 8, 2026
24d ago
ANALYST-DOWNGRADE
BEARISH ★ 4/10
$393.17 $375.65▲ +4.46%▲ +3.34%$403.04 (−2.51%)
Aug 14, 2026
7w ago
Court Ruling
BULLISH ★ 7/10
$415.21 $439.33▲ +5.81%▲ +7.18%$403.04 (−2.93%)
Aug 13, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$415.21 $439.33▲ +5.81%▲ +7.18%$403.04 (−2.93%)
Aug 11, 2026
7w ago
Court Ruling
NEUTRAL ★ 3/10
$414.30 $425.28▲ +2.65%▲ +3.05%$403.04 (−2.72%)
Aug 7, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$417.20 $419.38▲ +0.52%▲ +0.57%$403.04 (−3.39%)
Aug 7, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$417.20 $419.38▲ +0.52%▲ +0.57%$403.04 (−3.39%)
Aug 7, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$417.20 $419.38▲ +0.52%▲ +0.57%$403.04 (−3.39%)
Aug 4, 2026
8w ago
GOVT-CONTRACT
NEUTRAL ★ 3/10
$390.02 $414.30▲ +6.23%▲ +6.33%$403.04 (+3.34%)
Jul 31, 2026
9w ago
8-K
BEARISH ★ 5/10
$378.87 $417.20▼ −10.12%▼ −8.09%$403.04 (−6.38%)
Showing 10 of 16

US Market Status

Market Closed — Opens Mon (38h 35m)

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Report published Apr 21, 2026