Nasdaq· Biological Products, (No Diagnostic Substances)· Inc. DE· CIK 0001806310

TSHA

Taysha Gene Therapies, Inc.
$4.63 ▼ -2.32%
Prev close $4.74
Market cap$1.6B
ConsensusStrong Buy
12-mo target$13.00 (+180.8%)
▲ Bullish
Analyst conviction 9/10
High Impact Filing (7/10)30 New Institutional Positions10 Institutional Exits Biotech & Drug Discovery
Snapshot
The big-picture read on TSHA right now — valuation, ownership and activity at a glance.
Market Cap
$1.6B
Cap Size
Small Cap
Analyst Consensus
Strong Buy (94%)
Inst. Holders
50 funds
Inst. Value
$1.5B
Inst. Activity
30 buys / 10 sells
Insider Activity
$0.00 buy / $2.1M sell
Insider Net $
-$2.1M
SEC Reports
8
Press Releases
4
Price chart 30d -16.9%
Daily candles (open–high–low–close) with volume. Green = up day, red = down day.
Vol
Recent activity
The latest filings, insider trades, analyst actions, press and options flow — newest first.
Oct 2, 2026 other
Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
DALLAS, Oct. 02, 2026 (GLOBE NEWSWIRE) -- Taysha Gene Therapies, Inc. (Nasdaq: TSHA) (Taysha or the
Aug 11, 2026 SEC
Taysha Gene Therapies reported Q2 2026 EPS of -$0.13, missing consensus of -$0.11 by 18.2%, with zero revenue vs. $1.99M
PRESS-RELEASE — Impact 5/10
Jul 10, 2026 Insider
Nagendran Sukumar sold 200,000 shares
President and Head of R&D @ $6.24 ($1.2M)
Jun 30, 2026 Inst.
WELLINGTON MANAGEMENT GROUP LLP — DOUBLED
3,975,605 shares ($27.1M)
Jun 30, 2026 Inst.
HEALTHCARE OF ONTARIO PENSION — ADD
3,885,501 shares ($26.5M)
Jun 26, 2026 SEC
Taysha Gene Therapies is raising approximately $187.4 million ($215.6 million if underwriters' option is exercised) thro
424B5 — Impact 6/10
Jun 26, 2026 SEC
Taysha Gene Therapies priced a $200M underwritten public offering of 32,500,001 common shares at $6.00/share and 833,333
8-K — Impact 5/10
Jun 25, 2026 Press
Taysha Gene Therapies announced the pricing of a $200M underwritten public offering of 32.5M shares at $6.00/share, plus
Impact 7/10
Analyst ratings buy % -1.1%
How Wall Street rates the stock today, and the latest firm-by-firm actions.
Strong Buy 94% rate it Buy or better · 18 analysts
Strong Buy 6 33% Buy 11 61% Hold 1 6% Sell 0 0% Strong Sell 0 0%
Recent analyst actions
DateFirmActionRatingFirm rating
Sep 17, 2026Wolfe ResearchINITIATEOutperform 52%
Jul 21, 2026Goldman SachsMAINTAINBuy 54%
Jul 2, 2026CitizensREITERATEMarket Outperform 38%
Jun 30, 2026NeedhamMAINTAINBuy 50%
Jun 30, 2026BairdMAINTAINOutperform 54%
Jun 23, 2026BMO CapitalMAINTAINOutperform 53%
Jun 23, 2026B of A SecuritiesMAINTAINBuy 54%
Jun 23, 2026CitizensMAINTAINMarket Outperform 38%
Jun 22, 2026NeedhamMAINTAINBuy 50%
Apr 6, 2026Canaccord GenuityMAINTAINBuy 47%
Monthly consensus history
PeriodStr. BuyBuyHoldSellStr. SellBuy %Distribution
Sep 1, 202661110094%
Aug 1, 202661110094%
Jul 1, 202661210095%
Jun 1, 202661210095%
May 1, 202661310095%
Apr 1, 202661310095%
Mar 1, 202661310095%
Feb 1, 202661310095%
Price targets
Where 13 covering analysts think TSHA trades over the next 12 months.
$13.00 +180.8% upside Strong Buy
Current$4.63 Low$9.00 Median$12.00 High$19.00 13 analysts
$9.00$19.00
Analyst rating Strong Buy· 1.2/5 as of Oct 2, 2026
Reports & filings
AI-scored summaries of recent SEC filings and press releases, with sentiment and impact.
8 SEC filing reports analyzed · 0 bullish, 1 bearish, 2 mixed, 5 neutral · avg impact 4.4/10.Plus 4 press releases.
Upcoming & catalyst events
Scheduled dates plus disclosed catalysts — earnings, dividends, enforcement, FDA and clinical-trial events. Colored dot = impact.
Oct 2, 2026
other
Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
DALLAS, Oct. 02, 2026 (GLOBE NEWSWIRE) -- Taysha Gene Therapies, Inc. (Nasdaq: TSHA) (Taysha or the Company), a clinical-stage biotechnology company f
Oct 1, 2026
short_volume
Short Volume: TSHA — 69.2% short (0.5M / 0.8M)
Short: 538,550 | Exempt: 172 | TRF Vol: 778,127 | Short Ratio: 69.2% | Off-exchange volume (dark pool + OTC)
Sep 30, 2026
short_volume
Short Volume: TSHA — 83.5% short (0.9M / 1.0M)
Short: 865,350 | Exempt: 75 | TRF Vol: 1,035,773 | Short Ratio: 83.5% | Off-exchange volume (dark pool + OTC)
Sep 29, 2026
short_volume
Short Volume: TSHA — 83.1% short (1.0M / 1.3M)
Short: 1,049,032 | Exempt: 230 | TRF Vol: 1,262,662 | Short Ratio: 83.1% | Off-exchange volume (dark pool + OTC)
Sep 25, 2026
short_volume
Short Volume: TSHA — 67.8% short (0.9M / 1.3M)
Short: 852,627 | Exempt: 65 | TRF Vol: 1,257,142 | Short Ratio: 67.8% | Off-exchange volume (dark pool + OTC)
Earnings estimates
Forecast earnings per share and revenue by period — and whether estimates are rising.
PeriodEPS Est.RangeGrowth30d RevUp/DnRevenue#
Current Q$-0.13$-0.14–$-0.10-42.9%-4.2%0↑ 3↓$0.0B4
Next Q$-0.13$-0.15–$-0.11-81.1%-15.2%0↑ 3↓$0.0B4
Current FY$-0.47$-0.58–$-0.38-49.1%-7.7%0↑ 3↓$0.0B5
Next FY$-0.46$-0.53–$-0.432.4%-6.3%0↑ 3↓$0.0B4
Current-quarter EPS estimate — revision history
WhenEPS estimateChange vs now
Current$-0.125—
7d ago$-0.125—
30d ago$-0.120-0.005
60d ago$-0.120-0.005
90d ago$-0.122-0.003
Institutional ownership
Which big funds own TSHA (from quarterly 13F filings) and who is adding or trimming.
50 institutional holders with $1.5B total value (223,080,887 shares) as of 2026-Q2. Top holders: Avoro, RA, GOLDMAN. Net buying activity: 30 institutions added/increased vs 10 reduced.
Top holders — 2026-Q2
FundSharesValue% TrackedLast move
Avoro Capital Advisors LLC23,888,888$162.7M10.7%—
RA CAPITAL MANAGEMENT, L.P.23,555,648$160.4M10.6%—
GOLDMAN SACHS GROUP INC22,713,118$154.7M10.2%—
BlackRock, Inc.20,691,927$140.9M9.3%—
MORGAN STANLEY16,487,479$112.3M7.4%—
RTW INVESTMENTS, LP13,560,258$92.3M6.1%—
FMR LLC13,336,413$90.8M6.0%—
VANGUARD CAPITAL MANAGEMENT LLC12,478,595$85.0M5.6%—
STATE STREET CORP11,421,920$77.8M5.1%—
GEODE CAPITAL MANAGEMENT, LLC6,560,394$44.7M2.9%—
Recent position changes
FundActionPrevCurrentChangeValue
WELLINGTON MANAGEMENT GROUP LLPDOUBLED626,3613,975,605+534.7%$27.1M
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUNDADD2,883,3013,885,501+34.8%$26.5M
VANGUARD PORTFOLIO MANAGEMENT LLCADD2,022,4983,140,009+55.3%$21.4M
Pictet Asset Management Holding SADOUBLED19,3182,770,701+14242.6%$18.9M
Aberdeen Group plcDOUBLED1,021,0632,327,152+127.9%$15.8M
FARALLON CAPITAL MANAGEMENT, L.L.C.NEW—2,250,000—$15.3M
NORGES BANKNEW—2,233,600—$15.2M
MILLENNIUM MANAGEMENT LLCTRIM3,281,8202,126,838-35.2%$14.5M
BARCLAYS PLCTRIM2,812,0101,630,659-42.0%$11.1M
CITADEL ADVISORS LLCDOUBLED411,1351,535,287+273.4%$10.5M
Insider activity
Buying and selling by company executives and directors (SEC Form 4).
6 insiders, 12 transactions. Net -$2.1M — $0.00 bought, $2.1M sold.
DateInsiderTitleTypeSharesPriceValue
Jul 10, 2026Nagendran SukumarPresident and Head of R&DSELL200,000$6.24$1.2M
Jun 1, 2026Long Alison SDirectorAWARD21,335——
Jun 1, 2026Stalfort John A IIIDirectorAWARD21,335——
Jun 1, 2026Long Alison SDirectorAWARD42,671——
Jun 1, 2026Donenberg Phillip B.DirectorAWARD21,335——
Jun 1, 2026Donenberg Phillip B.DirectorAWARD42,671——
Jun 1, 2026Sepp-Lorenzino LauraDirectorAWARD42,671——
Jun 1, 2026Stalfort John A IIIDirectorAWARD42,671——
Jun 1, 2026Sepp-Lorenzino LauraDirectorAWARD21,335——
Apr 10, 2026Nagendran SukumarPresident and Head of R&DEXERCISE19,021$1.71$32.5K
Short interest & halts
FINRA semi-monthly short positions, Reg SHO threshold status, and recent trading halts for TSHA.
Shares short
51,405,384
Settlement Sep 15, 2026
Change vs prior
+9.8%
Semi-monthly cycle
Days to cover
18.8
At avg daily volume
Of shares outstanding
≈15.8%
Estimate — not % of float
All TSHA filing & press-release reports (12)