Nasdaq· Pharmaceutical Preparations· Inc. DE· CIK 0001933414

MLYS

Mineralys Therapeutics, Inc.
$23.91 ▲ +0.78%
Prev close $23.72
Market cap$2.2B
12-mo target$48.50 (+102.9%)
Insider Selling Cluster (3 insiders)High Impact Filing (7/10)35 New Institutional Positions15 Institutional Exits Biotech & Drug Discovery
Snapshot
The big-picture read on MLYS right now — valuation, ownership and activity at a glance.
Market Cap
$2.2B
Cap Size
Mid Cap
Inst. Holders
50 funds
Inst. Value
$1.4B
Inst. Activity
35 buys / 15 sells
Insider Activity
$0.00 buy / $10.8M sell
Insider Net $
-$10.8M
SEC Reports
17
Press Releases
5
Price chart 30d -17.7%
Daily candles (open–high–low–close) with volume. Green = up day, red = down day.
Vol
Recent activity
The latest filings, insider trades, analyst actions, press and options flow — newest first.
Dec 22, 2026 fda_pdufa
PDUFA: MLYS — lorundrostat in hypertension — 2026-12-22
FDA target action date 2026-12-22 for MLYS (Mineralys Therapeutics, Inc.). Drug: lorundrostat. Indic
Sep 22, 2026 Insider
Slingsby Brian Taylor sold 104,320 shares
Director @ $28.81 ($3.0M)
Sep 21, 2026 Insider
Warren Eric acquired via exercise 7,438 shares
Chief Commercial Officer @ $13.24 ($98.5K)
Sep 21, 2026 Insider
Warren Eric sold 7,438 shares
Chief Commercial Officer @ $28.12 ($209.1K)
Aug 12, 2026 SEC
James J. Ferguson III filed an initial statement of beneficial ownership (Form 3) with the SEC, disclosing his appointme
3 — Impact 2/10
Jul 23, 2026 SEC
Two C-suite insiders at Mineralys Therapeutics sold shares totaling ~$211K in open-market transactions after exercising
CLUSTER — Impact 2/10
Jul 21, 2026 SEC
CEO Jon Congleton and CMO David Malcom Rodman sold a combined ~$302K in MLYS stock over a 7-day window, with the CEO's $
CLUSTER — Impact 3/10
Jun 30, 2026 Inst.
BlackRock, Inc. — ADD
5,887,038 shares ($158.8M)
Analyst ratings buy % +1.1%
How Wall Street rates the stock today, and the latest firm-by-firm actions.
Recent analyst actions
DateFirmActionRatingFirm rating
Apr 27, 2026TD CowenINITIATEBuy 56%
Monthly consensus history
PeriodStr. BuyBuyHoldSellStr. SellBuy %Distribution
Sep 1, 20265920088%
Aug 1, 20265920088%
Jul 1, 20265920088%
Jun 1, 20265920088%
May 1, 20265920088%
Apr 1, 20265820087%
Mar 1, 20265820087%
Feb 1, 20265820087%
Price targets
Where 8 covering analysts think MLYS trades over the next 12 months.
$48.50 +102.9% upside Strong Buy
Current$23.91 Low$30.00 Median$52.00 High$56.00 8 analysts
$30.00$56.00
Analyst rating None as of Oct 2, 2026
Reports & filings
AI-scored summaries of recent SEC filings and press releases, with sentiment and impact.
17 SEC filing reports analyzed · 1 bullish, 1 bearish, 1 mixed, 14 neutral · avg impact 3.2/10.Plus 5 press releases.
Upcoming & catalyst events
Scheduled dates plus disclosed catalysts — earnings, dividends, enforcement, FDA and clinical-trial events. Colored dot = impact.
Dec 22, 2026
fda_pdufa
PDUFA: MLYS — lorundrostat in hypertension — 2026-12-22
FDA target action date 2026-12-22 for MLYS (Mineralys Therapeutics, Inc.). Drug: lorundrostat. Indication: hypertension. FDA assigned PDUFA target act
Oct 1, 2026
other
Mineralys Therapeutics Announces Presentation of Lorundrostat Data at American Heart Association Hypertension Scientific Sessions 2026
RADNOR, Pa., Oct. 01, 2026 (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicine
Sep 29, 2026
activist
Mineralys Therapeutics Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)
RADNOR, Pa., Sept. 29, 2026 (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicin
Sep 24, 2026
other
Mineralys Therapeutics to Participate in the Stifel 2026 Virtual Cardiometabolic Forum
RADNOR, Pa., Sept. 24, 2026 (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicin
Sep 23, 2026
other
Mineralys Therapeutics’ Transform-HTN Open-Label Extension Trial Data Selected for Late-Breaking Presentation at American Heart Association Scientific Sessions 2026
RADNOR, Pa., Sept. 23, 2026 (GLOBE NEWSWIRE) -- Mineralys Therapeutics, Inc. (Nasdaq: MLYS), a biopharmaceutical company focused on developing medicin
Earnings estimates
Forecast earnings per share and revenue by period — and whether estimates are rising.
PeriodEPS Est.RangeGrowth30d RevUp/DnRevenue#
Current Q$-0.53$-0.60–$-0.39-2.8%+5.2%4↑ 2↓$0.0B7
Next Q$-0.59$-0.73–$-0.45-47.9%+6.5%3↑ 2↓$0.0B7
Current FY$-4.43$-4.63–$-3.93-93.4%-97.8%0↑ 7↓$0.0B7
Next FY$-2.50$-3.78–$-1.2043.5%-19.3%2↑ 5↓$0.1B8
Current-quarter EPS estimate — revision history
WhenEPS estimateChange vs now
Current$-0.534—
7d ago$-0.564+0.029
30d ago$-0.564+0.029
60d ago$-0.564+0.029
90d ago$-0.569+0.034
Institutional ownership
Which big funds own MLYS (from quarterly 13F filings) and who is adding or trimming.
50 institutional holders with $1.4B total value (53,315,053 shares) as of 2026-Q2. Top holders: NOMURA, RA, BlackRock,. Net buying activity: 35 institutions added/increased vs 15 reduced.
Top holders — 2026-Q2
FundSharesValue% TrackedLast move
NOMURA ASSET MANAGEMENT CO LTD0$0.000.0%—
RA CAPITAL MANAGEMENT, L.P.7,692,750$207.6M14.4%—
BlackRock, Inc.5,887,038$158.8M11.0%ADD +31.4%
FMR LLC4,511,689$121.7M8.5%—
STATE STREET CORP4,141,636$111.7M7.8%ADD +41.1%
VANGUARD CAPITAL MANAGEMENT LLC2,756,770$74.4M5.2%—
Capital World Investors1,997,607$53.9M3.7%DOUBLED +401.7%
FRANKLIN RESOURCES INC1,635,520$44.1M3.1%—
GEODE CAPITAL MANAGEMENT, LLC1,584,326$42.8M3.0%—
BANK OF AMERICA CORP /DE/1,505,547$40.6M2.8%ADD +36.8%
Recent position changes
FundActionPrevCurrentChangeValue
BlackRock, Inc.ADD4,481,5825,887,038+31.4%$158.8M
STATE STREET CORPADD2,935,9404,141,636+41.1%$111.7M
Capital World InvestorsDOUBLED398,1791,997,607+401.7%$53.9M
BANK OF AMERICA CORP /DE/ADD1,100,3721,505,547+36.8%$40.6M
GOLDMAN SACHS GROUP INCADD785,0431,458,676+85.8%$39.4M
Pictet Asset Management Holding SAADD1,034,4381,430,649+38.3%$38.6M
MILLENNIUM MANAGEMENT LLCDOUBLED525,2601,221,758+132.6%$33.0M
WELLINGTON MANAGEMENT GROUP LLPNEAR_EXIT3,359,068806,716-76.0%$21.8M
TUDOR INVESTMENT CORP ET ALDOUBLED155,740738,370+374.1%$19.9M
Aberdeen Group plcNEW—689,235—$18.6M
Insider activity
Buying and selling by company executives and directors (SEC Form 4).
6 insiders, 50 transactions. Net -$10.8M — $0.00 bought, $10.8M sold.
DateInsiderTitleTypeSharesPriceValue
Sep 22, 2026Slingsby Brian TaylorDirectorSELL104,320$28.81$3.0M
Sep 21, 2026Warren EricChief Commercial OfficerEXERCISE7,438$13.24$98.5K
Sep 21, 2026Warren EricChief Commercial OfficerSELL7,438$28.12$209.1K
Sep 15, 2026Karydas DaphneDirectorEXERCISE3,000$12.02$36.1K
Sep 15, 2026Karydas DaphneDirectorSELL3,000$28.58$85.7K
Aug 21, 2026Warren EricChief Commercial OfficerEXERCISE7,437$13.24$98.5K
Aug 21, 2026Warren EricChief Commercial OfficerSELL7,437$25.98$193.2K
Aug 10, 2026Ferguson James J. IIIChief Medical OfficerAWARD102,400——
Aug 10, 2026Rodman David MalcomChief Medical OfficerEXERCISE2,170$16.00$34.7K
Aug 10, 2026Rodman David MalcomChief Medical OfficerSELL2,170$27.09$58.8K
Short interest & halts
FINRA semi-monthly short positions, Reg SHO threshold status, and recent trading halts for MLYS.
Shares short
9,181,891
Settlement Sep 15, 2026
Change vs prior
-1.6%
Semi-monthly cycle
Days to cover
6.4
At avg daily volume
Of shares outstanding
≈10.4%
Estimate — not % of float
All MLYS filing & press-release reports (22)