| MANE | CLUSTER | neutral | 3/10 | CEO Reid Alexander and Director John Childs sold a combined $2.82M in open-market MANE shares within a week of Veradermi | Aug 18, 2026 |
| STOK | CLUSTER | neutral | 3/10 | Two Stoke Therapeutics insiders, a director and the general counsel, executed open-market sales totaling $469K on August | Aug 18, 2026 |
| GILD | CLUSTER | neutral | 2/10 | Two GILD C-suite executives (CFO and Chief Communications & Corporate Affairs Officer) sold a combined $2.69M in open-ma | Aug 18, 2026 |
| IRON | CLUSTER | neutral | 2/10 | CEO John Quisel and COO Jonathan Yu sold a combined $723K in open-market shares following derivative exercises. The CEO' | Aug 18, 2026 |
| JNJ | CLUSTER | neutral | 2/10 | CEO Joaquin Duato and EVP Jennifer Taubert sold a combined $30.65M in open-market stock over a 5-day window, with Duato' | Aug 18, 2026 |
| ABCL | CLUSTER | bullish | 5/10 | Three AbCellera insiders, including the CFO and two directors, purchased a total of ~$975K in open-market shares over a | Aug 18, 2026 |
| APLM | CLUSTER | bullish | 8/10 | Three top executives at Apollomics (CEO, CFO, COO) collectively purchased $2.25M of APLM stock in open-market transactio | Aug 18, 2026 |
| DYN | CLUSTER | bearish | 6/10 | Director Jason P. Rhodes sold ~$65.2M worth of DYN shares (1.4% of market cap) in a cluster over two days, while CEO Joh | Aug 18, 2026 |
| ZVRA | CLUSTER | neutral | 3/10 | Two ZVRA insiders, the Chief Legal & Compliance Officer and a Director, sold a combined $613K in open-market transaction | Aug 18, 2026 |
| APLM | CLUSTER | bullish | 6/10 | Apollomics CFO and COO made open-market purchases totaling $700K at $15/share, representing ~1% of the $68M market cap. | Aug 17, 2026 |
| EWTX | CLUSTER | neutral | 4/10 | Five C-suite insiders at Edgewise Therapeutics sold a total of ~$401K in open-market shares on August 12, 2026, followin | Aug 17, 2026 |
| CUE | CLUSTER | bearish | 6/10 | CEO Shao-Lee Lin sold ~$1.6M of CUE shares in open-market sales last week, and VP Meluzio sold ~$169K, both after exerci | Aug 17, 2026 |
| ORKA | CLUSTER | neutral | 2/10 | Two senior insiders at Oruka Therapeutics (CMO and General Counsel) executed large-derivative exercises and sold shares | Aug 17, 2026 |
| RCKT | CLUSTER | neutral | 4/10 | Three Rocket Pharmaceuticals insiders, including the CEO and COO, sold a total of $154K in open-market sales over a 7-da | Aug 17, 2026 |
| RYTM | CLUSTER | neutral | 4/10 | Three Rhythm Pharmaceuticals executives sold a total of $9.77M in open-market stock within a week of the company's stron | Aug 17, 2026 |
| SEPN | CLUSTER | bearish | 7/10 | Septerna insiders sold $40.2M in stock over a 7-day window, led by a $31.7M open-market sale by director/10% owner RA Ca | Aug 15, 2026 |
| AMRX | CLUSTER | mixed | 5/10 | Amneal Pharmaceuticals insiders sold $7.1M in stock over a 7-day window, including the EVP of Legal and an Executive VP, | Aug 15, 2026 |
| BCAX | CLUSTER | neutral | 5/10 | No summary provided | Aug 15, 2026 |
| DNTH | CLUSTER | neutral | 4/10 | Multiple Dianthus Therapeutics insiders, including CEO Marino and GC Veness, executed open-market sales totaling $3.15M | Aug 15, 2026 |
| JNJ | CLUSTER | neutral | 2/10 | JNJ CEO Joaquin Duato and EVP/Chief Legal Officer Elizabeth Forminard sold a combined $29.11M in open-market shares over | Aug 15, 2026 |
| MEDP | CLUSTER | neutral | 4/10 | Medpace CEO August Troendle sold $21.1M in stock over a 3-day window (Aug 10-12), with a director selling an additional | Aug 15, 2026 |
| TWST | CLUSTER | neutral | 4/10 | Multiple Twist Bioscience insiders, including CEO Emily Leproust, sold a combined $6.37M of stock over a 7-day window. T | Aug 15, 2026 |
| INCY | CLUSTER | bearish | 4/10 | Two top R&D executives at Incyte sold a combined $1.57M in stock over a 7-day window. President Pablo Cagnoni sold $1.30 | Aug 15, 2026 |
| EWTX | CLUSTER | neutral | 3/10 | CEO Kevin Koch and General Counsel John Moore sold a combined ~$468K in open-market sales on August 12, 2026, following | Aug 15, 2026 |
| CORT | CLUSTER | neutral | 3/10 | Two C-suite insiders at Corcept Therapeutics sold shares on August 10, 2026, totaling $662K in open-market sales. The sa | Aug 15, 2026 |
| UTHR | CLUSTER | neutral | 3/10 | CEO Martine Rothblatt sold ~$7.1M in open-market shares over two days (Aug 12-13), exercising options at $135.42 and imm | Aug 15, 2026 |
| IRON | CLUSTER | neutral | 2/10 | Two senior insiders at Disc Medicine (IRON), the COO and Chief Legal Officer, sold a combined $466K in open-market sales | Aug 14, 2026 |
| SEPN | CLUSTER | bearish | 6/10 | Two insiders at Septerna sold a combined $32.83M in open-market transactions within a 7-day window, representing 1.6% of | Aug 14, 2026 |
| LGND | CLUSTER | neutral | 4/10 | CFO Octavio Espinoza and Director Jason Haas executed a cluster of derivative exercises and open-market sales on August | Aug 14, 2026 |
| TWST | CLUSTER | bearish | 6/10 | Twist Bioscience CEO Emily Leproust sold $14.2M of stock via a derivative exercise-and-sell transaction, while two direc | Aug 14, 2026 |