Insider Cluster (8 insiders) ·Filed May 26, 2026

TWST

Twist Bioscience Corp
NEUTRAL
Impact 3/10
Horizondays Processed4mo ago
Insider cluster: 2 insiders, $296K total
Actionable Insight • Neutral

The lack of material dollar amounts relative to $3.8B market cap means this cluster is unlikely to move the stock on its own. However, if TWST is near a catalyst event (earnings, pipeline data, or M&A), the simultaneous C-suite liquidation could amplify bearish positioning. Monitor for any subsequent 8-K or Form 144 filings that might indicate the sales were part of a larger block trade. With the cross-filing amplifiers triggered (cluster + earnings/agreement/press context), any forthcoming material announcement should be viewed through the lens of insider selling having preceded it.

DirectionNeutral
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
TWST ▲ +112.45% at T+60d
NEUTRAL call ✓ call won +112.45% · α vs SPY +110.57% · entry $64.17 → $136.33
Entry anchored
May 26, 03:59 PM ET
via exchange tick
T+1d
+7.57%
call +7.57% · α +7.03%
$69.03
settled 4mo ago
T+5d
+9.32%
call +9.32% · α +8.11%
$70.15
settled 4mo ago
T+20d
+50.62%
call +50.62% · α +52.52%
$96.65
settled 3mo ago
T+60d
+112.45%
call +112.45% · α +110.57%
$136.33
settled 6w ago

Price Chart

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Executive Summary

Six TWST insiders—including the CEO, CFO, and COO—collectively sold 16,796 shares for ~$807K on May 21, 2026, all at $53.257. While this represents only ~0.02% of the $3.8B market cap (well below the 0.1% materiality threshold), the uniformity of execution on a single day at an identical price suggests a coordinated liquidity event (e.g., share settlement upon vesting) rather than opportunistic selling. However, the simultaneous sale by the entire C-suite introduces modest cautionary color, especially given the stock's recent run-up.

Key Financial Metrics

Direction
selling
Total Value
$1.1M
Insiders
8

Key Facts

  • Six insiders sold on May 21, 2026, at $53.257/share: CEO (6,888 sh), CFO (2,019 sh), COO (4,160 sh), CAO (688 sh), SVP HR (1,399 sh), and a VP-level executive (1,642 sh)
  • Total cluster value is ~$807K, representing ~0.02% of TWST's $3.8B market cap
  • All six trades executed on the same day at an identical price, consistent with a pre-arranged 10b5-1 plan or tax-related share withholding on a vesting event
  • No open-market purchases occurred in this cluster
  • The cluster sale value is trivial relative to market cap (0.02%), falling below the 0.1% floor for material insider selling

Financial Impact

~$807K total insider sales, or ~0.02% of market cap — immaterial by both absolute and relative measures

dilutioninsider ownership

Risk Factors

  • If the May 21 sales were opportunistic rather than 10b5-1-scheduled, the identical-price same-day cluster signals potential shared negative information among the C-suite
  • Back-to-back insider selling by different cohorts (this cluster + the 8 trades for $1.9M in the prior 30 days) could pressure sentiment even at small dollar amounts

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
88% bullish (16 analysts)

Investment Themes

Biotech & Drug DiscoveryGenomics & Gene Editing

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-TWST-1779826026297
27 reports for TWST
Performance horizon
88% Hit rate 7 of 8 directional calls best @ T+60▲ +52.11%May 4, 2026
Filters
Rows
Reports for TWST — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$127.22 $166.99▲ +31.26%▲ +31.60%$187.45 (+47.34%)
Aug 27, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$153.10 $128.71▼ −15.93%▼ −16.20%$187.45 (+22.44%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$151.42 $132.06▼ −12.79%▼ −12.25%$187.45 (+23.79%)
Aug 21, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$145.59 $141.38▼ −2.89%▼ −3.37%$187.45 (+28.75%)
Aug 20, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$136.23 $153.10▲ +12.38%▲ +11.27%$187.45 (+37.60%)
Aug 14, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$124.41 $140.80▲ +13.17%▲ +14.36%$187.45 (+50.67%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$124.41 $140.80▼ −13.17%▼ −14.36%$187.45 (−50.67%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 12, 2026
7w ago
144
NEUTRAL ★ 2/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 11, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$123.12 $116.10▼ −5.70%▼ −5.30%$187.45 (+52.25%)
Showing 10 of 27

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Report published May 26, 2026