Insider Cluster (7 insiders) ·Filed Jun 1, 2026

TWST

Twist Bioscience Corp
NEUTRAL
Impact 3/10
Horizondays Processed4mo ago
Insider cluster: 7 insiders, $0.7M total
Actionable Insight • Neutral

The CEO's sales are mechanically tied to option exercises and follow a pattern seen in prior periods — not a fresh bearish signal. The dollar amount is trivial relative to market cap. No actionable trading signal from this cluster alone. Monitor the next 10-Q for any fundamental deterioration that would justify a more cautious stance.

DirectionNeutral
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
TWST ▲ +113.91% at T+60d
NEUTRAL call ✓ call won +113.91% · α vs SPY +112.80% · entry $70.15 → $150.06
Entry anchored
Jun 1, 03:59 PM ET
via exchange tick
T+1d
+3.11%
call +3.11% · α +3.80%
$72.33
settled 4mo ago
T+5d
-0.13%
call -0.13% · α +2.84%
$70.06
settled 4mo ago
T+20d
+45.76%
call +45.76% · α +47.32%
$102.25
settled 3mo ago
T+60d
+113.91%
call +113.91% · α +112.80%
$150.06
settled 5w ago

Price Chart

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Executive Summary

A cluster of insider selling at Twist Bioscience over the past week, led by CEO Emily Leproust who sold ~$3.2M in open-market shares alongside option exercises, while the CAO and a director also sold smaller amounts. The total open-market sales of ~$4.0M represent ~0.1% of the $4.2B market cap, falling at the low end of the proportionality band. The CEO's sales are part of a regular pattern tied to option exercises, reducing their informational signal per the academic literature.

Key Financial Metrics

Direction
selling
Total Value
$4.0M
Insiders
7

Key Facts

  • CEO Emily Leproust sold 49,516 shares open-market for ~$3.2M across May 26-28, all tied to same-day option exercises at $8.82 or $0 strike
  • CAO Robert Werner sold 800 shares for ~$50K on May 26
  • Director Melissa Starovasnik sold 3,000 shares for ~$201K across May 26 and May 28
  • Total open-market sales in the cluster: ~$4.0M, or ~0.1% of market cap
  • Non-cash option exercises (M transactions) by CEO totaled $0 economic value for 65,769 shares
  • Prior 30-day insider activity showed 5 sells totaling $3.4M, consistent with ongoing selling pattern

Financial Impact

Total open-market sales of ~$4.0M, representing ~0.1% of $4.2B market cap

dilutioninsider ownership

Risk Factors

  • CEO selling alongside option exercises could be misinterpreted as bearish by the market
  • If the company reports disappointing earnings in the next quarter, the insider sales may be viewed in hindsight as informed

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
88% bullish (16 analysts)

Investment Themes

Biotech & Drug DiscoveryGenomics & Gene Editing

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-TWST-1780344427670
27 reports for TWST
Performance horizon
88% Hit rate 7 of 8 directional calls best @ T+60▲ +52.11%May 4, 2026
Filters
Rows
Reports for TWST — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$127.22 $166.99▲ +31.26%▲ +31.60%$187.45 (+47.34%)
Aug 27, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$153.10 $128.71▼ −15.93%▼ −16.20%$187.45 (+22.44%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$151.42 $132.06▼ −12.79%▼ −12.25%$187.45 (+23.79%)
Aug 21, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$145.59 $141.38▼ −2.89%▼ −3.37%$187.45 (+28.75%)
Aug 20, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$136.23 $153.10▲ +12.38%▲ +11.27%$187.45 (+37.60%)
Aug 14, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$124.41 $140.80▲ +13.17%▲ +14.36%$187.45 (+50.67%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$124.41 $140.80▼ −13.17%▼ −14.36%$187.45 (−50.67%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 12, 2026
7w ago
144
NEUTRAL ★ 2/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 11, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$123.12 $116.10▼ −5.70%▼ −5.30%$187.45 (+52.25%)
Showing 10 of 27

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Report published Jun 1, 2026