Insider Cluster (6 insiders) ·Filed Feb 23, 2026

TWST

Twist Bioscience Corp
BEARISH
Impact 6/10
Horizondays Processed7mo ago
Actionable Insight ▼ Bearish

Traders should monitor for potential downward pressure on TWST shares, especially if this selling follows weak fundamentals or precedes an earnings release. The uniformity of the transaction date and price suggests pre-arranged 10b5-1 plans, but the concentration of C-suite participation raises concerns about confidence in near-term performance.

DirectionBearish
Confidencehigh
Horizondays
Final — all horizons settled through T+60d ⚠ clustered
TWST ▲ +3.54% at T+60d
SHORT call ✗ call lost -3.54% · α vs SPY +4.72% · entry $48.09 → $49.79
Entry anchored
Feb 20, 03:59 PM ET
via exchange tick
T+1d
+0.94%
call -0.94% · α -0.20%
$48.54
settled 7mo ago
T+5d
-4.57%
call +4.57% · α +5.19%
$45.89
settled 7mo ago
T+20d
-7.47%
call +7.47% · α +3.52%
$44.50
settled 7mo ago
T+60d
+3.54%
call -3.54% · α +4.72%
$49.79
settled 5mo ago

Price Chart

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Executive Summary

Six insiders at Twist Bioscience Corp, including the CEO, COO, CFO, and other executives, sold shares in a coordinated open-market transaction on February 23, 2026, totaling approximately $821,000 in sales. All transactions occurred at the same price and date, indicating a planned divestment rather than opportunistic trading.

Key Financial Metrics

Direction
selling
Total Value
$821.4K
Insiders
6

Key Facts

  • CEO Emily Leproust sold 7,205 shares for $336,544, the largest individual sale in the cluster.
  • President and COO Patrick Finn sold 4,294 shares for $200,572.
  • CFO Adam Laponis sold 2,085 shares for $97,390.
  • All six insiders executed identical open-market sales on the same day at $46.7098 per share.
  • Total value of the cluster: $821,438.54 in open-market selling by corporate insiders.

Financial Impact

$821,438 in insider selling over a single day

insider ownershipinvestor sentimentshareholder dilution risk (if proceeds used for operations)

Risk Factors

  • Perception of lack of confidence from top leadership, particularly the CEO and COO.
  • Potential for follow-on selling if other insiders participate in similar plans.
  • Negative market reaction due to clustering of sales among key executives.

Market Snapshot

Exchange
Nasdaq

Investment Themes

Biotech & Drug DiscoveryGenomics & Gene Editing

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (6 trades, 7d window)cluster-TWST-1772109101826
27 reports for TWST
Performance horizon
86% Hit rate 6 of 7 directional calls best @ T+60▲ +52.11%May 4, 2026
Filters
Rows
Reports for TWST — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$127.22 $166.99▲ +31.26%▲ +31.60%$187.45 (+47.34%)
Aug 27, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$153.10 $128.71▼ −15.93%▼ −16.20%$187.45 (+22.44%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$151.42 $132.06▼ −12.79%▼ −12.25%$187.45 (+23.79%)
Aug 21, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$145.59 $141.38▼ −2.89%▼ −3.37%$187.45 (+28.75%)
Aug 20, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$136.23 $153.10▲ +12.38%▲ +11.27%$187.45 (+37.60%)
Aug 14, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$124.41 $140.80▲ +13.17%▲ +14.36%$187.45 (+50.67%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$124.41 $140.80▼ −13.17%▼ −14.36%$187.45 (−50.67%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 12, 2026
7w ago
144
NEUTRAL ★ 2/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 11, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$123.12 $116.10▼ −5.70%▼ −5.30%$187.45 (+52.25%)
Showing 10 of 27

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Report published Feb 26, 2026