Insider Cluster (7 insiders) ·Filed Aug 25, 2026

TWST

Twist Bioscience Corp
NEUTRAL
Impact 4/10
Horizondays Processed1mo ago
Insider cluster: 3 insiders, $2.5M total
Actionable Insight • Neutral

The cluster is too small relative to market cap to be material. The simultaneous C-suite selling on Aug 21 at identical prices strongly suggests a 10b5-1 plan execution or blackout-window opening, not a coordinated bearish view. Monitor for any upcoming earnings or material news that could have triggered a blackout window closing, but no immediate trading action is warranted.

DirectionNeutral
Confidencemedium
Horizondays
Latest settled — T+20d
TWST ▲ +4.68% at T+20d
NEUTRAL call ✓ call won +4.68% · α vs SPY +3.70% · entry $151.42 → $158.50
Next anchor: T+60d in 7w
Latest observation: T+25 +9.93% FF3 residual α
Entry anchored
Aug 24, 07:49 PM ET
via 1-min bar
T+1d
-0.90%
call -0.90% · α -0.92%
$150.06
settled 5w ago
T+5d
-12.79%
call -12.79% · α -12.25%
$132.06
settled 5w ago
T+20d
+4.68%
call +4.68% · α +3.70%
$158.50
settled 10d ago
T+60d
—
call — · α —
—
in 7w

Price Chart

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Executive Summary

A cluster of insider sales at Twist Bioscience, totaling ~$2.50M over a week, with the CEO, CFO, COO, and other senior executives all selling on the same day (Aug 21). While the dollar amount is modest relative to the $9.3B market cap (~0.027%), the unanimity of C-suite selling on a single date is notable. The sales are likely driven by a shared blackout-window opening or 10b5-1 plan, not a bearish signal, given the academic literature showing cluster sales are not predictive of negative returns.

Key Financial Metrics

Direction
selling
Total Value
$2.5M
Insiders
7

Key Facts

  • CEO Emily Leproust sold 6,639 shares for ~$923K on Aug 21
  • CFO Adam Laponis sold 1,965 shares for ~$273K on Aug 21
  • COO Patrick Finn sold 4,046 shares for ~$563K on Aug 21
  • Chief Accounting Officer Robert Werner sold 854 shares for ~$120K on Aug 24
  • Total cluster value ~$2.50M, representing ~0.027% of $9.3B market cap
  • All C-suite sales occurred on Aug 21 at the same price ($139.066), suggesting a coordinated or plan-driven event

Financial Impact

Total insider sales of ~$2.50M, a trivial 0.027% of market cap

insider ownership

Risk Factors

  • Insider sales could be misinterpreted as a bearish signal by the market
  • If the sales are not plan-driven, they may indicate management's lack of confidence in near-term prospects

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
94% bullish (16 analysts)

Investment Themes

Biotech & Drug DiscoveryGenomics & Gene Editing

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-TWST-1787728174018
27 reports for TWST
Performance horizon
88% Hit rate 7 of 8 directional calls best @ T+60▲ +52.11%May 4, 2026
Filters
Rows
Reports for TWST — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$127.22 $166.99▲ +31.26%▲ +31.60%$187.45 (+47.34%)
Aug 27, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$153.10 $128.71▼ −15.93%▼ −16.20%$187.45 (+22.44%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$151.42 $132.06▼ −12.79%▼ −12.25%$187.45 (+23.79%)
Aug 21, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$145.59 $141.38▼ −2.89%▼ −3.37%$187.45 (+28.75%)
Aug 20, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$136.23 $153.10▲ +12.38%▲ +11.27%$187.45 (+37.60%)
Aug 14, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$124.41 $140.80▲ +13.17%▲ +14.36%$187.45 (+50.67%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$124.41 $140.80▼ −13.17%▼ −14.36%$187.45 (−50.67%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 12, 2026
7w ago
144
NEUTRAL ★ 2/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 11, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$123.12 $116.10▼ −5.70%▼ −5.30%$187.45 (+52.25%)
Showing 10 of 27

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Report published Aug 26, 2026