Insider Cluster (4 insiders) ·Filed Aug 21, 2026

TWST

Twist Bioscience Corp
NEUTRAL
Impact 4/10
Horizondays Processed1mo ago
Insider cluster: 4 insiders, $8.5M total
Actionable Insight • Neutral

The cluster is small relative to market cap and dominated by a single insider's cashless option exercise/sale pattern, which is typical for tax planning. Monitor for any 8-K or press release that could explain the timing — the stock's recent +23% run may simply be providing a favorable exit window. No immediate bearish read-through given the proportionality and academic evidence that cluster sales are not predictive.

DirectionNeutral
Confidencemedium
Horizondays
Latest settled — T+20d ⚠ clustered
TWST ▲ +14.70% at T+20d
NEUTRAL call ✓ call won +14.70% · α vs SPY +14.98% · entry $145.59 → $166.99
Next anchor: T+60d in 6w
Latest observation: T+27 +10.96% FF3 residual α
Entry anchored
Aug 20, 07:27 PM ET
via 1-min bar
T+1d
-3.29%
call -3.29% · α -3.00%
$140.80
settled 6w ago
T+5d
-2.89%
call -2.89% · α -3.37%
$141.38
settled 5w ago
T+20d
+14.70%
call +14.70% · α +14.98%
$166.99
settled 14d ago
T+60d
—
call — · α —
—
in 6w

Price Chart

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Executive Summary

Four Twist Bioscience insiders, including CEO Emily Leproust and President/COO Patrick Finn, sold a total of $8.48M in stock over a 7-day window. The cluster is dominated by the President/COO's $11.0M in sales (including cashless exercise of options) and the CEO's $2.5M sale. While the dollar amount is modest relative to the $9.0B market cap (~0.09%), the concentration of C-suite selling at elevated prices near all-time highs warrants attention, though the academic literature finds cluster sales are not reliably informative.

Key Financial Metrics

Direction
selling
Total Value
$8.5M
Insiders
4

Key Facts

  • 4 insiders sold a total of $8.48M in TWST stock over 7 days
  • CEO Emily Leproust sold 20,000 shares for $2.50M on 2026-08-12
  • President/COO Patrick Finn sold ~78,355 shares for $11.0M (including cashless option exercises) on 2026-08-18
  • Director Katryn Blake sold 2,200 shares for $275K on 2026-08-12
  • VP Dennis Cho sold 14,205 shares for $1.84M on 2026-08-19
  • Total sales represent ~0.09% of TWST's $9.0B market cap
  • Stock is up ~23% in the past 2 weeks and trading near all-time highs

Financial Impact

Total insider sales of $8.48M represent ~0.09% of market cap — below the 0.1% materiality threshold

insider ownershipdilution

Risk Factors

  • C-suite selling at elevated prices could signal peak sentiment or insider caution
  • CEO and President/COO selling simultaneously may raise governance questions
  • Stock's recent parabolic move (+23% in 2 weeks) increases mean-reversion risk

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
94% bullish (16 analysts)

Investment Themes

Biotech & Drug DiscoveryGenomics & Gene Editing

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-TWST-1787379007205
27 reports for TWST
Performance horizon
88% Hit rate 7 of 8 directional calls best @ T+60▲ +52.11%May 4, 2026
Filters
Rows
Reports for TWST — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$127.22 $166.99▲ +31.26%▲ +31.60%$187.45 (+47.34%)
Aug 27, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$153.10 $128.71▼ −15.93%▼ −16.20%$187.45 (+22.44%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$151.42 $132.06▼ −12.79%▼ −12.25%$187.45 (+23.79%)
Aug 21, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$145.59 $141.38▼ −2.89%▼ −3.37%$187.45 (+28.75%)
Aug 20, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$136.23 $153.10▲ +12.38%▲ +11.27%$187.45 (+37.60%)
Aug 14, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$124.41 $140.80▲ +13.17%▲ +14.36%$187.45 (+50.67%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$124.41 $140.80▼ −13.17%▼ −14.36%$187.45 (−50.67%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 12, 2026
7w ago
144
NEUTRAL ★ 2/10
$125.29 $136.23▲ +8.73%▲ +10.70%$187.45 (+49.61%)
Aug 11, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$123.12 $116.10▼ −5.70%▼ −5.30%$187.45 (+52.25%)
Showing 10 of 27

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Report published Aug 22, 2026