Institutional Cluster

TRVI

Trevi Therapeutics, Inc.
MIXED
Impact 5/10
Horizonweeks Processed3mo ago
Institutional cluster: 4 buyers, 3 sellers (mixed)
Actionable Insight ◆ Mixed

The divergence between active asset managers (AllianceBernstein, Fidelity) adding heavily and Morgan Stanley/BofA exiting suggests a catalyst-driven thesis (likely pipeline data) that not all institutions agree on. Monitor upcoming clinical trial readouts or regulatory milestones for TRVI; the active buying cluster signals conviction but the selling cluster warns of potential overhang.

DirectionMixed
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
TRVI ▲ +28.23% at T+60d
NEUTRAL call ✓ call won +28.23% · α vs SPY +23.84% · entry $13.46 → $17.26
Entry anchored
Jun 11, 02:25 PM ET
via exchange tick
T+1d
+5.57%
call +5.57% · α +5.03%
$14.21
settled 4mo ago
T+5d
+21.62%
call +21.62% · α +21.19%
$16.37
settled 4mo ago
T+20d
+36.70%
call +36.70% · α +34.81%
$18.40
settled 3mo ago
T+60d
+28.23%
call +28.23% · α +23.84%
$17.26
settled 24d ago

Executive Summary

Four institutional buyers accumulated $90.6M in TRVI during Q4 2025, led by Fidelity ($51.2M add) and AllianceBernstein ($38.6M new position), while three sellers reduced holdings by $29.4M, notably Morgan Stanley exiting 75.6% of its position ($26.2M). The net $61.2M inflow is dominated by active asset managers, suggesting conviction in Trevi's pipeline catalysts, but the cluster is mixed with significant passive selling.

Key Financial Metrics

Direction
mixed
Buy Value
$121.3M
Sell Value
$29.4M
Net Flow
$61.2M

Institutional Positions

Net institutional flow: $61.2M

▲ Buyers (4)

InstitutionActionChangePosition ValueValue Δ
FidelityADD+97%$81.4M$51.2M
AlliancebernsteinNEW—$38.6M$38.6M
Wells FargoADD+81.9%$1.3M$758.0K
Mirae Asset Global InvestmentsADD+32.3%$78.0K$35.0K

▼ Sellers (3)

InstitutionActionChangePrev ValueValue Δ
Morgan StanleyNEAR_EXIT-75.6%$39.4M-$26.2M
BofATRIM-40.4%$16.8M-$3.1M
Two SigmaTRIM-30.2%$1.1M-$48.7K

Key Facts

  • 4 buyers added $90.6M in aggregate; 3 sellers reduced $29.4M
  • Fidelity added 3.2M shares (+97%), now holding $81.4M
  • AllianceBernstein initiated a new $38.6M position (3.08M shares)
  • Morgan Stanley near-exited, selling 3.25M shares (-75.6%) for $26.2M
  • BofA trimmed 40.4% of its position, selling $3.1M worth
  • Two Sigma quant fund trimmed 30.2% of its small position

Financial Impact

Net institutional inflow of $61.2M (buyers $90.6M minus sellers $29.4M), representing roughly 3.2% of $1.9B market cap

institutional ownershipfloatshare price

Risk Factors

  • Morgan Stanley's near-exit could indicate negative non-public information or portfolio rebalancing unrelated to fundamentals
  • 13F data is 45+ days stale; positions may have been unwound since quarter-end
  • Cluster is mixed (4 buyers vs 3 sellers), reducing directional conviction
  • Passive buyers (Fidelity, Wells Fargo) may reflect index rebalancing rather than active conviction

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
94% bullish (17 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-TRVI-2025-Q4
10 reports for TRVI
Performance horizon
100% Hit rate 3 of 3 directional calls best @ T+60▲ +15.38%Mar 9, 2026
Filters
Rows
Reports for TRVI — sortable, filterable
TypeNow
Jun 11, 2026
16w ago
Institutional Cluster
MIXED ★ 5/10
$13.46 $17.26▲ +28.23%▲ +23.84%—
Jun 11, 2026
16w ago
Institutional Cluster
MIXED ★ 4/10
$13.46 $17.26▲ +28.23%▲ +23.84%—
Apr 21, 2026
23w ago
DEFA14A
NEUTRAL ★ 3/10
$14.80 $19.07▲ +28.85%▲ +24.07%—
Apr 20, 2026
23w ago
Press Release
NEUTRAL ★ 5/10
$14.62 $17.36▲ +18.74%▲ +11.84%—
Apr 17, 2026
23w ago
424B5
BEARISH ★ 7/10
$15.40 $18.15▼ −17.82%▼ −11.05%—
Apr 17, 2026
24w ago
8-K
BEARISH ★ 7/10
$15.23 $17.91▼ −17.60%▼ −11.45%—
Apr 17, 2026
24w ago
Press Release
NEUTRAL ★ 6/10
$15.23 $17.91▲ +17.60%▲ +11.45%—
Mar 17, 2026
28w ago
Press Release
MIXED ★ 6/10
$10.69 $13.46▲ +25.91%▲ +14.39%—
Mar 10, 2026
29w ago
Press Release
NEUTRAL ★ 3/10
$11.94 $13.45▲ +12.65%▲ +1.12%—
Mar 9, 2026
29w ago
Press Release
BULLISH ★ 7/10
$11.70 $13.50▲ +15.38%▲ +3.40%—
Showing 10 of 10

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Report published Jun 11, 2026