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8-K ·Filed May 14, 2026

TPST

Tempest Therapeutics, Inc.
BEARISH
Impact 7/10
Horizonimmediate Processed5mo ago SEC0001193125-26-224156
8-K Item 2.02: Earnings release
Actionable Insight ▼ Bearish

The $1.8M cash balance is critically low for a company planning to initiate a U.S. registrational study. Expect an imminent dilutive equity offering (following the pattern of $8.35M RDO in Nov 2025 and $6M PIPE in Mar 2026). The 100% CR rate in TPST-2003 is a genuine catalyst but the financing overhang will dominate near-term price action. Monitor for a capital raise announcement within weeks.

DirectionBearish
Confidencehigh
Horizonimmediate
Final — all horizons settled through T+60d
TPST ▼ -35.52% at T+60d
SHORT call ✓ call won +35.52% · α vs SPY +40.03% · entry $1.83 → $1.18
Entry = T+0 close
May 14, 2026
via day close
T+1d
-0.55%
call +0.55% · α +0.48%
$1.82
settled 6mo ago
T+5d
+1.64%
call -1.64% · α -0.68%
$1.86
settled 5mo ago
T+20d
-31.69%
call +31.69% · α +33.81%
$1.25
settled 5mo ago
T+60d
-35.52%
call +35.52% · α +40.03%
$1.18
settled 3mo ago

Price Chart

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Executive Summary

Tempest Therapeutics reported Q1 2026 results with a net loss of $27.7M ($2.53/share), significantly wider than the $10.9M loss in Q1 2025, driven by $22.1M in acquired in-process R&D costs from the Factor Bioscience asset acquisition. Cash burned rapidly to $1.8M from $7.7M at year-end 2025, highlighting acute near-term funding risk for a clinical-stage biotech with no revenue and a planned registrational study.

Key Financial Metrics

EPS
−$2.53
est −$0.28 · -803.6%
Rating
strong miss

Key Facts

  • Cash and cash equivalents fell to $1.8M as of March 31, 2026, from $7.7M on December 31, 2025 — a 77% decline in one quarter
  • Net loss of $27.7M for Q1 2026 vs $10.9M in Q1 2025, driven by $22.1M in acquired in-process R&D expense
  • Operating loss of $27.7M vs $10.9M in the prior-year quarter, with R&D spending collapsing to $0.1M from $7.6M
  • At the current burn rate (~$6M/quarter excluding the one-time acquisition costs), the company has less than one quarter of cash runway
  • No revenue reported; pre-revenue clinical-stage biotech with no approved products
  • Positive interim TPST-2003 data (100% CR rate in 15 CAR-T-naive patients) is the key pipeline catalyst but does not offset the cash crisis

Financial Impact

Cash burn of ~$5.9M in operating activities (excluding $22.1M non-cash IPR&D charge) leaves ~$1.8M cash, implying <1 quarter runway without additional financing

cashnet lossoperating lossR&D spend

Risk Factors

  • Imminent need for dilutive financing — cash runway is <1 quarter at current burn
  • Potential going-concern qualification in next 10-Q if no financing secured
  • Dilution from the March 2026 private placement warrants (up to $4M additional shares)
  • Clinical trial execution risk for planned TPST-2003 registrational study

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
86% bullish (7 analysts)

Investment Themes

Documents Analyzed

This report is based on 6 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001193125-26-224156
Document: tpst-20260514.htm0001193125-26-224156
Document: 0001193125-26-224156-index-headers.html0001193125-26-224156
Document: 0001193125-26-224156-index.html0001193125-26-224156
Document: 0001193125-26-224156.txt0001193125-26-224156
8-K Data (Synthetic)0001193125-26-224156
27 reports for TPST
Performance horizon
77% Hit rate @ T+20 10 of 13 directional calls Went positive at some point 12 of 14 best @ T+60▲ +39.55%May 22, 2026
Filters
Rows
Reports for TPST — sortable, filterable
TypeNow
Oct 26, 2026
1d ago
DEF 14A
BEARISH ★ 6/10
$0.5102awaiting T+20—$0.5110 (−0.16%)
Oct 20, 2026
7d ago
DEFA14A
NEUTRAL ★ 4/10
$0.5282awaiting T+20—$0.5110 (−3.26%)
Oct 20, 2026
7d ago
8-K
NEUTRAL ★ 3/10
$0.5282awaiting T+20—$0.5110 (−3.26%)
Oct 19, 2026
8d ago
8-K
NEUTRAL ★ 2/10
$0.5762awaiting T+20—$0.5110 (−11.32%)
Oct 2, 2026
25d ago
EFFECT
BEARISH ★ 6/10
$0.8112awaiting T+20—$0.5110 (+37.01%)
Sep 25, 2026
4w ago
S-3
BEARISH ★ 6/10
$0.8316 $0.5102▲ +38.65%▲ +38.62%$0.5110 (+38.55%)
Sep 17, 2026
5w ago
8-K
BULLISH ★ 6/10
$0.9680 $0.6240▼ −35.54%▼ −35.74%$0.5110 (−47.21%)
Sep 16, 2026
5w ago
DEFA14A
NEUTRAL ★ 5/10
$0.8950 $0.6350▼ −29.05%▼ −30.51%$0.5110 (−42.91%)
Sep 16, 2026
5w ago
8-K
NEUTRAL ★ 4/10
$0.8950 $0.6350▼ −29.05%▼ −30.51%$0.5110 (−42.91%)
Sep 11, 2026
6w ago
Press Release
BEARISH ★ 6/10
$0.8117 $0.7601▲ +6.36%▲ +8.23%$0.5110 (+37.05%)
Showing 10 of 27

US Market Status

Market Closed — Opens Thu (10h 49m)

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Report published May 14, 2026