Institutional Cluster

TNGX

Tango Therapeutics, Inc.
BULLISH
Impact 5/10
Horizonweeks Processed3mo ago
Institutional cluster: 10 buyers, 2 sellers (bullish)
Actionable Insight ▲ Bullish

The cluster indicates strong institutional interest, but given TNGX's historical patterns of weak follow-through (43% win rate at T+20), traders should look for a near-term catalyst (e.g., pipeline data, partnership) to confirm the thesis before acting. The involvement of both passive and active funds suggests a broad re-rating thesis.

DirectionBullish
Confidencemedium
Horizonweeks
Latest settled — T+20d ⚠ clustered
TNGX ▲ +2.35% at T+20d
LONG call ✓ call won +2.35% · α vs SPY +0.46% · entry $29.82 → $30.52
Next anchor: T+60d due 24d ago
Latest observation: T+58 -48.20% FF3 residual α
Entry anchored
Jun 11, 01:22 PM ET
via exchange tick
T+1d
+3.76%
call +3.76% · α +3.21%
$30.94
settled 4mo ago
T+5d
+8.28%
call +8.28% · α +7.85%
$32.29
settled 4mo ago
T+20d
+2.35%
call +2.35% · α +0.46%
$30.52
settled 3mo ago
T+60d
—
call — · α —
—
due 24d ago

Executive Summary

A strong institutional accumulation cluster emerged in TNGX during Q3 2025, with 10 funds net buying $96.6M vs. 2 sellers trimming only $0.7M. Point72 initiated a notable $24.5M position, while passive giants Vanguard, State Street, and Invesco also substantially increased holdings. This represents ~2.4% of TNGX's $4.1B market cap and signals broad conviction, though historical reports on TNGX have shown limited follow-through.

Key Financial Metrics

Direction
accumulating
Buy Value
$130.7M
Sell Value
$4.1M
Net Flow
$95.9M

Institutional Positions

Net institutional flow: $95.9M

▲ Buyers (10)

InstitutionActionChangePosition ValueValue Δ
Point72NEW—$24.5M$24.5M
State StreetDOUBLED+143.4%$28.3M$21.2M
VanguardADD+25.5%$42.4M$21.8M

▼ Sellers (2)

InstitutionActionChangePrev ValueValue Δ
Morgan StanleyTRIM-52.9%$2.7M-$622.2K
UBSTRIM-42.1%$1.4M-$70.7K

Key Facts

  • 10 institutional buyers added $96.6M net, while only 2 sellers trimmed $0.7M
  • Point72 (quant) opened a new $24.5M position, the largest active buyer
  • State Street (passive) doubled its stake to $28.3M, and Vanguard (passive) added $21.8M to reach $42.4M
  • Two Sigma (quant) and Franklin Resources (active) also made significant additions
  • Sellers Morgan Stanley and UBS trimmed modestly, reducing by $0.6M and $0.07M respectively

Financial Impact

Net institutional inflow of $95.9M, representing ~2.4% of TNGX's $4.1B market cap

institutional ownershipfloat held by tracked institutions

Risk Factors

  • Passive buying may reflect index rebalancing rather than stock-specific conviction
  • Historical performance on TNGX shows limited positive return persistence after cluster signals
  • Point72's new position could be momentum-driven and may reverse quickly

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
78% bullish (18 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-TNGX-2025-Q3
19 reports for TNGX
Performance horizon
57% Hit rate 4 of 7 directional calls best @ T+60▲ +29.28%Jun 8, 2026
Filters
Rows
Reports for TNGX — sortable, filterable
TypeNow
Aug 11, 2026
7w ago
8-K
BEARISH ★ 6/10
$25.58 $25.20▲ +1.49%▲ +1.04%—
Aug 11, 2026
7w ago
8-K
BULLISH ★ 7/10
$26.34 $25.44▼ −3.42%▼ −3.01%—
Aug 11, 2026
7w ago
Press Release
BULLISH ★ 7/10
$26.34 $25.44▼ −3.42%▼ −3.01%—
Aug 9, 2026
7w ago
Institutional Cluster
BULLISH ★ 6/10
$27.67 $25.29▼ −8.60%▼ −8.55%—
Aug 6, 2026
8w ago
8-K
NEUTRAL ★ 2/10
$27.07 $25.60▼ −5.43%▼ −5.83%—
Jun 11, 2026
16w ago
144
NEUTRAL ★ 2/10
$30.94 $27.97▼ −9.60%▼ −10.27%—
Jun 11, 2026
16w ago
Institutional Cluster
BULLISH ★ 5/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 4/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 10, 2026
16w ago
424B5
MIXED ★ 6/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 10, 2026
16w ago
144
NEUTRAL ★ 2/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Showing 10 of 19

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Report published Jun 11, 2026