Institutional Cluster

TNGX

Tango Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonweeks Processed3mo ago
Institutional cluster: 5 buyers, 0 sellers (bullish)
Actionable Insight • Neutral

The cluster is purely passive/index-driven — no active manager conviction signal. Monitor Q1 2026 13F filings for active fund participation; if active managers remain absent despite the 78% analyst bullishness, it suggests skepticism about near-term catalysts. The stock's +10.53% avg T+20 return on prior reports is misleadingly high — 43% win rate indicates high volatility, not reliable alpha.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+20d ⚠ clustered
TNGX ▲ +2.35% at T+20d
NEUTRAL call ✓ call won +2.35% · α vs SPY +0.46% · entry $29.82 → $30.52
Next anchor: T+60d due 24d ago
Latest observation: T+58 -48.20% FF3 residual α
Entry anchored
Jun 10, 03:59 PM ET
via exchange tick
T+1d
+3.76%
call +3.76% · α +3.21%
$30.94
settled 4mo ago
T+5d
+8.28%
call +8.28% · α +7.85%
$32.29
settled 4mo ago
T+20d
+2.35%
call +2.35% · α +0.46%
$30.52
settled 3mo ago
T+60d
—
call — · α —
—
due 24d ago

Executive Summary

Five mega-passive institutional investors (Vanguard, BlackRock, State Street, Fidelity, Morgan Stanley) collectively added $108.3M to their TNGX positions in Q4 2025, increasing aggregate holdings to $228.6M. The buying is entirely passive/index-driven, reflecting TNGX's inclusion or increased weighting in major indices, not active fundamental conviction. With zero sellers and a 78% bullish analyst consensus, the cluster confirms institutional baseline demand but lacks active-manager alpha signal.

Key Financial Metrics

Direction
accumulating
Buy Value
$228.6M
Net Flow
$108.3M

Institutional Positions

Net institutional flow: $108.3M

▲ Buyers (5)

InstitutionActionChangePosition ValueValue Δ
VanguardADD+33.6%$59.8M$17.4M
BlackRockADD+51.2%$75.7M$28.2M
State StreetADD+84.8%$55.1M$26.8M
FidelityDOUBLED+44524.2%$25.4M$25.4M
Morgan StanleyDOUBLED+464.7%$12.6M$10.5M

Key Facts

  • 5 mega-passive funds added $108.3M net to TNGX in Q4 2025
  • Aggregate institutional holdings rose to $228.6M from $120.3M
  • All buyers are passive/index managers (Vanguard, BlackRock, State Street, Fidelity, Morgan Stanley)
  • Zero institutional sellers in the cluster
  • Fidelity and Morgan Stanley more than quadrupled their positions from tiny bases
  • 78% of analysts rate TNGX as Buy or Strong Buy

Financial Impact

5 passive institutions accumulated $108.3M in new TNGX positions during Q4 2025, bringing total disclosed holdings to $228.6M

institutional ownershippassive fund flows

Risk Factors

  • No active manager buying — passive flows may reverse on index rebalancing
  • Historical 43% win rate on prior TNGX reports suggests high downside tail risk
  • Score calibration shows negative net alpha at T+20 across this segment (-1.14%)
  • 13F data is 45+ days stale; positions may have been unwound

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
78% bullish (18 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-TNGX-2025-Q4
19 reports for TNGX
Performance horizon
63% Hit rate 5 of 8 directional calls best @ T+60▲ +29.28%Jun 8, 2026
Filters
Rows
Reports for TNGX — sortable, filterable
TypeNow
Aug 11, 2026
7w ago
8-K
BEARISH ★ 6/10
$25.58 $25.20▲ +1.49%▲ +1.04%—
Aug 11, 2026
7w ago
8-K
BULLISH ★ 7/10
$26.34 $25.44▼ −3.42%▼ −3.01%—
Aug 11, 2026
7w ago
Press Release
BULLISH ★ 7/10
$26.34 $25.44▼ −3.42%▼ −3.01%—
Aug 9, 2026
7w ago
Institutional Cluster
BULLISH ★ 6/10
$27.67 $25.29▼ −8.60%▼ −8.55%—
Aug 6, 2026
8w ago
8-K
NEUTRAL ★ 2/10
$27.07 $25.60▼ −5.43%▼ −5.83%—
Jun 11, 2026
16w ago
144
NEUTRAL ★ 2/10
$30.94 $27.97▼ −9.60%▼ −10.27%—
Jun 11, 2026
16w ago
Institutional Cluster
BULLISH ★ 5/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 4/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 10, 2026
16w ago
424B5
MIXED ★ 6/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Jun 10, 2026
16w ago
144
NEUTRAL ★ 2/10
$29.82 $32.29▲ +8.28%▲ +7.85%—
Showing 10 of 19

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Report published Jun 11, 2026