SecBot SecBot
SC 13G ·Filed Sep 30, 2026

STOK

Stoke Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonweeks Processed25d 19h ago SEC0000921895-26-002685
Passive investor 5%+ stake
Actionable Insight • Neutral

Monitor for any future conversion to a 13D or increased activism, as BVF is a known healthcare-focused fund that sometimes engages with management. The passive filing suggests no near-term catalyst, but the 5.6% stake provides a base for potential future influence.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+5d
STOK ▼ -7.92% at T+5d
NEUTRAL call -7.92% · α vs SPY -9.22% · entry $26.01 → $23.95
Next anchor: T+20d tomorrow
Latest observation: T+16 +3.48% FF3 residual α
Entry = T+0 close
Sep 30, 2026
via day close
T+1d
-1.50%
call -1.50% · α -2.24%
$25.62
settled 25d ago
T+5d
-7.92%
call -7.92% · α -9.22%
$23.95
settled 19d ago
T+20d
Pending
tomorrow
T+60d
Pending
in 8w

Price Chart

Loading chart...

Executive Summary

Biotechnology Value Fund L.P. (BVF) and related entities filed a new Schedule 13G disclosing a 5.6% beneficial ownership stake in Stoke Therapeutics as of September 30, 2026. The filing is passive (Rule 13d-1(c)), indicating no intent to influence control. BVF GP Holdings LLC owns 5.1% and BVF Partners L.P./BVF Inc./Mark N. Lampert each own 5.6% on an aggregated basis. This is a new 13G filing (not an amendment) for BVF, which had not previously filed a 13G for Stoke in the provided cross-filing context (prior filings were by Fidelity and Lynx1 Capital). The stake is notable for its size and the reputation of BVF as a dedicated healthcare investor, but the passive filing limits immediate market impact.

Key Financial Metrics

Stake
5.6%
Investor
Biotechnology Value Fund L.P. (BVF) and related entities
Investor Type
hedge fund

Key Facts

  • BVF GP Holdings LLC beneficially owns 3,271,024 shares (5.1% of outstanding) as of September 30, 2026.
  • BVF Partners L.P., BVF Inc., and Mark N. Lampert each beneficially own 3,608,968 shares (5.6% of outstanding) on an aggregated basis.
  • The filing is made under Rule 13d-1(c), confirming a passive investment intent with no control influence.
  • The percentage calculations are based on 64,526,242 shares outstanding as of July 30, 2026 (per the issuer's 10-Q filed August 3, 2026).
  • This is a new Schedule 13G filing for BVF; prior 13G filings for Stoke were by Fidelity (August 2026) and Lynx1 Capital (May 2026).

Financial Impact

BVF entities hold a combined 5.6% stake valued at approximately $XX million based on current market price (not disclosed in filing).

ownership_percentage

Risk Factors

  • BVF could convert to an activist 13D filing in the future, potentially leading to management changes or strategic shifts.
  • The stake is relatively small (5.6%) and passive, limiting immediate influence on corporate actions.

Investment Themes

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G Filing (Primary)0000921895-26-002685
Document: 0000921895-26-002685-index-headers.html0000921895-26-002685
Document: 0000921895-26-002685-index.html0000921895-26-002685
Document: 0000921895-26-002685.txt0000921895-26-002685
12 reports for STOK
Performance horizon
50% Hit rate @ T+20 2 of 4 directional calls Went positive at some point 4 of 5 best @ T+60▲ +12.62%Mar 13, 2026
Filters
Rows
Reports for STOK — sortable, filterable
TypeNow
Oct 21, 2026
4d ago
144
BEARISH ★ 6/10
$25.70awaiting T+20—$25.31 (+1.52%)
Sep 30, 2026
25d ago
SC 13G
NEUTRAL ★ 4/10
$26.01awaiting T+20—$25.31 (−2.69%)
Sep 25, 2026
4w ago
8-K
NEUTRAL ★ 2/10
$25.50awaiting T+20—$25.31 (−0.75%)
Aug 18, 2026
9w ago
Insider Cluster
NEUTRAL ★ 3/10
$33.03 $28.93▼ −12.41%▼ −10.46%$25.31 (−23.37%)
Aug 3, 2026
11w ago
8-K
BEARISH ★ 6/10
$31.67 $30.89▲ +2.46%▲ +1.22%$25.31 (+20.08%)
Aug 3, 2026
11w ago
424B5
BEARISH ★ 6/10
$31.67 $30.89▲ +2.46%▲ +1.22%$25.31 (+20.08%)
Jun 30, 2026
16w ago
8-K
BULLISH ★ 6/10
$32.72 $29.31▼ −10.42%▼ −9.39%$25.31 (−22.65%)
May 7, 2026
24w ago
8-K
NEUTRAL ★ 4/10
$32.89 $30.01▼ −8.76%▼ −8.78%$25.31 (−23.05%)
Apr 22, 2026
26w ago
DEFA14A
NEUTRAL ★ 3/10
$34.93 $30.30▼ −13.27%▼ −17.90%$25.31 (−27.54%)
Apr 7, 2026
28w ago
8-K
NEUTRAL ★ 3/10
$34.87 $32.96▼ −5.48%▼ −14.02%$25.31 (−27.42%)
Showing 10 of 12

US Market Status

Market Open — Closes in 2h 16m

Subscribe to SecBot

Get Real-Time SEC Filing Intelligence

Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.

Create a free account Live analysis, Telegram alerts, watchlists and the MCP server for subscribers
Report published Sep 30, 2026