Institutional Cluster

SLNO

SOLENO THERAPEUTICS INC
MIXED
Impact 4/10
Horizonweeks Processed3mo ago
Institutional cluster: 7 buyers, 4 sellers (mixed)
Actionable Insight ◆ Mixed

The cluster is dominated by passive rebalancing (6 of 7 buyers are index/process-driven) while quant funds actively sold. This split suggests no concentrated fundamental catalyst. Monitor for an insider buy cluster or SC 13D filing if active conviction is needed. The historically poor T+20 win rate (33%) on prior SLNO calls argues against trading this signal alone.

DirectionMixed
Confidencemedium
Horizonweeks

Executive Summary

Six institutional investors accumulated $883.9M in SLNO (net +$345.5M) while four reduced holdings by -$139.4M. The buying is overwhelmingly passive/index-driven (Fidelity doubled to $540.8M, Invesco doubled to $101.4M, State Street, Schwab, UBS, Wells Fargo all added), while quant funds D.E. Shaw (-93.2%) and Citadel (-70.1%) made near-complete exits. The divergent signal between passive accumulation and active quant reduction suggests mechanical rebalancing rather than a shared fundamental thesis. No analyst sees upside (0% bullish consensus) and the model's prior T+20 calls on SLNO have only a 33% win rate, tempering conviction.

Key Financial Metrics

Direction
mixed
Buy Value
$883.9M
Sell Value
$677.9M
Net Flow
$205.5M

Institutional Positions

Net institutional flow: $205.5M

▲ Buyers (7)

InstitutionActionChangePosition ValueValue Δ
FidelityDOUBLED+139.7%$540.8M$261.1M
InvescoDOUBLED+132.3%$101.4M$47.3M
State StreetADD+54.7%$146.9M$29.2M

▼ Sellers (4)

InstitutionActionChangePrev ValueValue Δ
CitadelTRIM-70.1%$126.1M-$95.7M
D.E. ShawNEAR_EXIT-93.2%$9.6M-$9.1M
Morgan StanleyTRIM-62.3%$36.9M-$25.7M

Key Facts

  • 7 institutional buyers (6 passive/index) accumulated $883.9M total holdings, a net +$345.5M increase
  • 4 sellers (2 quant, 2 passive) reduced holdings by -$139.4M total
  • Fidelity doubled its stake to $540.8M, the single-largest position change
  • D.E. Shaw exited 93.2% and Citadel trimmed 70.1% of their positions
  • Analyst consensus is 0% bullish (0 buy, 13 hold, 3 sell/strong sell)
  • Model's prior SLNO calls have 33% win rate T+20; neutral reports have historically produced the largest moves

Financial Impact

Institutions added $345.5M net, with $883.9M total current institutional value vs $677.9M prior quarter; sellers reduced by $139.4M

institutional_ownership_pctfloat_held

Risk Factors

  • Passive buying may reverse at next index rebalance — there is no conviction signal
  • Quant selling from D.E. Shaw and Citadel indicates algorithmic models see deterioration
  • Zero bullish analyst coverage implies the sell-side agrees with the quant bears

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
0% bullish (16 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-SLNO-2025-Q3
10 reports for SLNO
Performance horizon
50% Hit rate 2 of 4 directional calls best @ T+60▲ +29.26%Feb 25, 2026
Filters
Rows
Reports for SLNO — sortable, filterable
TypeNow
Jun 11, 2026
16w ago
Institutional Cluster
BULLISH ★ 6/10
—awaiting T+1——
Jun 11, 2026
16w ago
Institutional Cluster
MIXED ★ 4/10
—awaiting T+1——
May 28, 2026
18w ago
15-12G
BEARISH ★ 8/10
—awaiting T+1——
May 28, 2026
18w ago
EFFECT
BEARISH ★ 5/10
—awaiting T+1——
May 18, 2026
19w ago
8-K / 25-NSE
BULLISH ★ 8/10
$53.01 $53.01· 0.00%▲ +0.65%—
Apr 7, 2026
25w ago
8-K
BEARISH ★ 7/10
$52.35 $52.60▼ −0.48%▲ +2.06%—
Apr 6, 2026
25w ago
8-K
BULLISH ★ 8/10
$52.25 $52.35▲ +0.19%▲ +0.13%—
Mar 27, 2026
27w ago
Insider Cluster
NEUTRAL ★ 3/10
$30.05 $30.44▲ +1.30%▲ +1.66%—
Feb 26, 2026
31w ago
8-K
NEUTRAL ★ 3/10
$38.09 $39.07▲ +2.57%▲ +3.03%—
Feb 25, 2026
31w ago
8-K
BULLISH ★ 8/10
$41.01 $38.09▼ −7.12%▼ −6.57%—
Showing 10 of 10

US Market Status

Market Closed — Opens Mon (64h 59m)

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Report published Jun 11, 2026