144 ·Filed Jun 26, 2026

SEPN

Septerna, Inc.
BEARISH
Impact 4/10
Horizonweeks Processed3mo ago SEC0001950047-26-006526
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

An officer's intent to sell ~$3.33M of stock, combined with a recent negative T+20 alpha trajectory for this issuer, suggests caution. Monitor for actual execution on Form 4 and any upcoming pipeline catalysts that may offset selling pressure.

DirectionBearish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
SEPN ▲ +16.20% at T+60d
SHORT call ✗ call lost -16.20% · α vs SPY -11.82% · entry $34.75 → $40.38
Entry anchored
Jun 26, 03:59 PM ET
via exchange tick
T+1d
-3.63%
call +3.63% · α +4.40%
$33.49
settled 3mo ago
T+5d
-3.68%
call +3.68% · α +5.07%
$33.47
settled 3mo ago
T+20d
-4.75%
call +4.75% · α +4.47%
$33.10
settled 2mo ago
T+60d
+16.20%
call -16.20% · α -11.82%
$40.38
settled 10d ago

Price Chart

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Executive Summary

Jae B. Kim, an officer of Septerna, Inc., filed a Form 144 on June 26, 2026, indicating intent to sell 94,339 shares of common stock, with an approximate market value of $3.33 million based on the filing date. This is a non-urgent intent filing, but the sell size relative to recent insider activity carries negative signal.

Key Facts

  • Form 144 filed by officer Jae B. Kim on 2026-06-26 for 94,339 shares of SEPN common stock.
  • Estimated market value of proposed sale: approximately $3.33 million ($35.26 per share).
  • Prior 30-day insider activity includes 3 sells totaling $547,000, so this filing more than quintuples known insider selling volume.
  • Shares to be sold were acquired via employee stock purchase plans (10/31/2025 and 04/30/2026) — not open-market buys.

Financial Impact

Proposed insider sale of ~$3.33M in SEPN stock (0.21% of $1.6B market cap).

Risk Factors

  • Insider sale may signal reduced conviction ahead of key clinical or operational milestones.
  • If sale executes, near-term technical overhang of ~94k shares could pressure the stock.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
93% bullish (15 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-006526
Document: 0001950047-26-006526-index.html0001950047-26-006526
Document: 0001950047-26-006526.txt0001950047-26-006526
17 reports for SEPN
Performance horizon
100% Hit rate 6 of 6 directional calls best @ T+60▲ +55.96%Apr 13, 2026
Filters
Rows
Reports for SEPN — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Press Release
NEUTRAL ★ 2/10
$38.51 $38.69▲ +0.47%▲ +0.69%$38.27 (−0.62%)
Sep 3, 2026
28d ago
3
NEUTRAL ★ 2/10
$36.75 $39.55▲ +7.62%▲ +8.83%$38.27 (+4.14%)
Aug 25, 2026
5w ago
8-K
NEUTRAL ★ 3/10
$41.30 $37.68▼ −8.77%▼ −8.23%$38.27 (−7.34%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 7/10
$44.20 $40.52▲ +8.33%▲ +7.14%$38.27 (+13.42%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$44.20 $40.52▲ +8.33%▲ +7.14%$38.27 (+13.42%)
Aug 12, 2026
7w ago
144
BEARISH ★ 5/10
$45.14 $40.79▲ +9.64%▲ +7.67%$38.27 (+15.22%)
Aug 12, 2026
7w ago
144
BEARISH ★ 5/10
$45.14 $40.79▲ +9.64%▲ +7.67%$38.27 (+15.22%)
Aug 10, 2026
7w ago
8-K
NEUTRAL ★ 4/10
$47.76 $43.80▼ −8.29%▼ −7.89%$38.27 (−19.87%)
Aug 10, 2026
7w ago
Press Release
NEUTRAL ★ 4/10
$47.76 $43.80▼ −8.29%▼ −7.89%$38.27 (−19.87%)
Jul 2, 2026
13w ago
Insider Cluster
NEUTRAL ★ 2/10
$34.00 $37.84▲ +11.29%▲ +10.36%$38.27 (+12.56%)
Showing 10 of 17

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