144 ·Filed Jun 22, 2026

SEPN

Septerna, Inc.
NEUTRAL
Impact 4/10
Horizondays Processed3mo ago SEC0001950047-26-006351
Form 144 — notice of proposed sale of securities
Actionable Insight • Neutral

This filing signals an insider's intent to take profits post-exercise. While the sale is not massive in absolute terms, the officer status and the recent cluster of insider sells (3 sells $621K in 30 days) warrant caution. Monitor for a follow-on Form 4 to confirm execution. The stock may face mild near-term selling pressure. Given the historical calibration for this filing-type shows negative average net alpha at T+20 (-1.98%), consider hedging or reducing exposure in the near term.

DirectionNeutral
Confidencemedium
Horizondays
Final — all horizons settled through T+60d
SEPN ▲ +5.11% at T+60d
NEUTRAL call ✓ call won +5.11% · α vs SPY +1.87% · entry $36.57 → $38.44
Entry anchored
Jun 22, 03:59 PM ET
via exchange tick
T+1d
-1.42%
call -1.42% · α -1.38%
$36.05
settled 3mo ago
T+5d
-4.98%
call -4.98% · α -5.99%
$34.75
settled 3mo ago
T+20d
-11.92%
call -11.92% · α -13.08%
$32.21
settled 2mo ago
T+60d
+5.11%
call +5.11% · α +1.87%
$38.44
settled 16d ago

Price Chart

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Executive Summary

Jae Kim, an officer of Septerna, filed a Form 144 to sell 94,339 shares valued at approximately $3.3 million. The sale stems from a stock option exercise, and the insider intends to sell on the open market. Given the company's size and the insider's role, this is a moderately notable signal of potential insider profit-taking.

Key Facts

  • Officer Jae Kim filed a Form 144 to sell 94,339 shares of common stock.
  • The proposed sale value is approximately $3.3 million based on the filing date.
  • The sale is related to a stock option exercise, not a secondary market purchase.
  • The filing date is June 22, 2026, and the sale is intended to occur soon.
  • As a percentage of market cap, the sale is roughly 0.2% ($3.3M / $1.6B).
  • Recent insider activity shows 3 sells totaling $621K in the last 30 days, making this a larger-than-average individual sale.

Financial Impact

Sale of ~$3.3 million worth of stock, approximately 0.2% of market cap. Not a controlling stake liquidation but a meaningful signal from an officer.

dilutioninsider sentiment

Risk Factors

  • Potential for insider sentiment to weigh on stock near-term as profit-taking is executed.
  • If additional insiders follow suit, could signal broader skepticism about valuation.
  • The sale may be tax-motivated or for personal diversification, reducing its predictive value.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
93% bullish (15 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-006351
Document: 0001950047-26-006351-index.html0001950047-26-006351
Document: 0001950047-26-006351.txt0001950047-26-006351
17 reports for SEPN
Performance horizon
100% Hit rate 7 of 7 directional calls best @ T+60▲ +55.96%Apr 13, 2026
Filters
Rows
Reports for SEPN — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Press Release
NEUTRAL ★ 2/10
$38.51 $38.69▲ +0.47%▲ +0.69%$38.27 (−0.62%)
Sep 3, 2026
28d ago
3
NEUTRAL ★ 2/10
$36.75 $39.55▲ +7.62%▲ +8.83%$38.27 (+4.14%)
Aug 25, 2026
5w ago
8-K
NEUTRAL ★ 3/10
$41.30 $37.68▼ −8.77%▼ −8.23%$38.27 (−7.34%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 7/10
$44.20 $40.52▲ +8.33%▲ +7.14%$38.27 (+13.42%)
Aug 14, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$44.20 $40.52▲ +8.33%▲ +7.14%$38.27 (+13.42%)
Aug 12, 2026
7w ago
144
BEARISH ★ 5/10
$45.14 $40.79▲ +9.64%▲ +7.67%$38.27 (+15.22%)
Aug 12, 2026
7w ago
144
BEARISH ★ 5/10
$45.14 $40.79▲ +9.64%▲ +7.67%$38.27 (+15.22%)
Aug 10, 2026
7w ago
8-K
NEUTRAL ★ 4/10
$47.76 $43.80▼ −8.29%▼ −7.89%$38.27 (−19.87%)
Aug 10, 2026
7w ago
Press Release
NEUTRAL ★ 4/10
$47.76 $43.80▼ −8.29%▼ −7.89%$38.27 (−19.87%)
Jul 2, 2026
13w ago
Insider Cluster
NEUTRAL ★ 2/10
$34.00 $37.84▲ +11.29%▲ +10.36%$38.27 (+12.56%)
Showing 10 of 17

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