144 ·Filed Sep 14, 2026

RYTM

RHYTHM PHARMACEUTICALS, INC.
BEARISH
Impact 5/10
Horizondays Processed17d 18h ago SEC0001950047-26-009442
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

Monitor for the actual Form 4 filing to confirm whether the sale was executed. A director/officer sale of this size (50k shares, ~$5.2M) at a $7.2B market cap is notable but not alarming on its own; watch for any pattern of additional insider selling or upcoming catalysts that could explain the timing.

DirectionBearish
Confidencemedium
Horizondays
Latest settled — T+5d
RYTM ▲ +2.58% at T+5d
SHORT call ✗ call lost -2.58% · α vs SPY -0.47% · entry $96.77 → $99.27
Next anchor: T+20d in 10d
Latest observation: T+10 +4.70% FF3 residual α
Entry anchored
Sep 14, 04:01 PM ET
via 1-min bar
T+1d
+1.28%
call -1.28% · α -1.72%
$98.01
settled 17d ago
T+5d
+2.58%
call -2.58% · α -0.47%
$99.27
settled 11d ago
T+20d
—
call — · α —
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in 10d
T+60d
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call — · α —
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in 2mo

Price Chart

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Executive Summary

David Meeker, a director and officer of Rhythm Pharmaceuticals, filed a Form 144 notice of intent to sell 50,000 shares of common stock with an approximate market value of $5.24 million. The shares are to be sold through Morgan Stanley and were acquired via stock option exercise. This is a notable insider sale from a top executive at a $7.2B market cap biotech, though the filing is an advance notice of intent, not a completed transaction.

Key Facts

  • David Meeker (Director and Officer) filed Form 144 to sell 50,000 shares.
  • Estimated sale value: ~$5,235,500 based on filing date market price.
  • Shares to be sold through Morgan Stanley Smith Barney LLC.
  • Shares acquired via exercise of stock options on 09/14/2026.
  • Filing date: 2026-09-14; proposed sale date also 09/14/2026.

Financial Impact

Proposed sale of 50,000 shares valued at approximately $5.24 million, representing about 0.07% of the company's $7.2B market cap.

dilutioninsider holdings

Risk Factors

  • Insider sale may signal reduced conviction ahead of a potential catalyst or earnings.
  • Form 144 is only an intent to sell; the sale may not be executed.
  • Stock option exercise and immediate sale could indicate tax planning rather than bearish view.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
87% bullish (23 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-009442
Document: 0001950047-26-009442-index.html0001950047-26-009442
Document: 0001950047-26-009442.txt0001950047-26-009442
18 reports for RYTM
Performance horizon
73% Hit rate 8 of 11 directional calls best @ T+60▲ +32.06%May 1, 2026
Filters
Rows
Reports for RYTM — sortable, filterable
TypeNow
Sep 14, 2026
17d ago
144
BEARISH ★ 5/10
$96.77 $99.27▼ −2.58%▼ −0.47%$93.68 (+3.19%)
Aug 17, 2026
6w ago
Insider Cluster
BEARISH ★ 6/10
$115.25 $113.35▲ +1.65%▲ +1.45%$93.68 (+18.72%)
Aug 17, 2026
6w ago
Insider Cluster
NEUTRAL ★ 4/10
$115.25 $113.35▼ −1.65%▼ −1.45%$93.68 (−18.72%)
Aug 4, 2026
8w ago
8-K
BULLISH ★ 7/10
$105.78 $112.85▲ +6.68%▲ +6.78%$93.68 (−11.44%)
Aug 4, 2026
8w ago
Press Release
BULLISH ★ 7/10
$105.78 $112.85▲ +6.68%▲ +6.78%$93.68 (−11.44%)
Jul 8, 2026
12w ago
Press Release
BULLISH ★ 6/10
$115.48 $106.09▼ −8.13%▼ −8.00%$93.68 (−18.88%)
Jun 22, 2026
14w ago
144
NEUTRAL ★ 2/10
$106.19 $110.04▲ +3.63%▲ +2.61%$93.68 (−11.78%)
Jun 15, 2026
15w ago
8-K
BULLISH ★ 6/10
$89.72 $106.19▲ +18.36%▲ +20.59%$93.68 (+4.41%)
Jun 15, 2026
15w ago
Press Release
BULLISH ★ 6/10
$89.72 $106.19▲ +18.36%▲ +20.59%$93.68 (+4.41%)
Jun 13, 2026
15w ago
Press Release
BULLISH ★ 7/10
$89.70 $101.39▲ +13.03%▲ +14.42%$93.68 (+4.44%)
Showing 10 of 18

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