144 ·Filed Sep 15, 2026

RVMD

Revolution Medicines, Inc.
NEUTRAL
Impact 4/10
Horizondays Processed16d 17h ago SEC0001294192-26-000005
Actionable Insight • Neutral

Two Form 144 notices filed 2026-09-15 signal insider selling intent at Revolution Medicines. Margaret A. Horn (Officer) intends to sell 29,600 shares (~$4.74M) via RSU vesting. Mark A. Goldsmith (Director) intends to sell 80,000 shares (~$16.74M) from trusts. Combined ~$21.5M in proposed sales. This follows 8 insider sells totaling $4.3M in the past 30 days. The sales are RSU-vesting and trust-related, not open-market discretionary, but the dollar amounts are material relative to recent insider activity. Market cap is $44.0B, so the sales are small relative to company size. Historical reports on RVMD show strong positive T+20 alpha (86% win rate), suggesting the stock has been in an uptrend; insider selling at elevated levels is a mild caution but not a reversal signal. Impact: moderate negative tilt, score 4.

DirectionNeutral
Confidencemedium
Horizondays
Latest settled — T+5d ⚠ clustered
RVMD ▼ -2.64% at T+5d
NEUTRAL call ✗ call lost -2.64% · α vs SPY -5.21% · entry $195.92 → $190.74
Next anchor: T+20d in 11d
Latest observation: T+10 -7.61% FF3 residual α
Entry anchored
Sep 15, 04:14 PM ET
via 1-min bar
T+1d
+0.52%
call +0.52% · α -0.61%
$196.94
settled 16d ago
T+5d
-2.64%
call -2.64% · α -5.21%
$190.74
settled 10d ago
T+20d
—
call — · α —
—
in 11d
T+60d
—
call — · α —
—
in 2mo

Price Chart

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Executive Summary

Two Form 144 notices filed 2026-09-15 signal insider selling intent at Revolution Medicines. Margaret A. Horn (Officer) intends to sell 29,600 shares (~$4.74M) via RSU vesting. Mark A. Goldsmith (Director) intends to sell 80,000 shares (~$16.74M) from trusts. Combined ~$21.5M in proposed sales. This follows 8 insider sells totaling $4.3M in the past 30 days. The sales are RSU-vesting and trust-related, not open-market discretionary, but the dollar amounts are material relative to recent insider activity. Market cap is $44.0B, so the sales are small relative to company size. Historical reports on RVMD show strong positive T+20 alpha (86% win rate), suggesting the stock has been in an uptrend; insider selling at elevated levels is a mild caution but not a reversal signal. Impact: moderate negative tilt, score 4.

Financial Impact

Not specified

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
93% bullish (28 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 6 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (RVMD) — Batch item 10001294192-26-000005
Document: 0001294192-26-000005-index.html0001246842-26-000006
Document: 0001294192-26-000005.txt0001294192-26-000005
144 Filing (RVMD) — Batch item 40001246842-26-000006
Document: 0001246842-26-000006-index.html0001294192-26-000005
Document: 0001246842-26-000006.txt0001294192-26-000005
26 reports for RVMD
Performance horizon
100% Hit rate 12 of 12 directional calls best @ T+60▲ +31.56%Apr 21, 2026
Filters
Rows
Reports for RVMD — sortable, filterable
TypeNow
Sep 15, 2026
16d ago
144
NEUTRAL ★ 2/10
$195.92 $190.74▼ −2.64%▼ −5.21%$206.54 (+5.42%)
Sep 15, 2026
16d ago
144
NEUTRAL ★ 4/10
$195.92 $190.74▼ −2.64%▼ −5.21%$206.54 (+5.42%)
Sep 15, 2026
17d ago
Insider Cluster
NEUTRAL ★ 2/10
$204.86 $190.95▼ −6.79%▼ −7.61%$206.54 (+0.82%)
Sep 14, 2026
17d ago
Insider Cluster
NEUTRAL ★ 3/10
$204.86 $192.86▼ −5.86%▼ −7.98%$206.54 (+0.82%)
Aug 26, 2026
5w ago
8-K
BULLISH ★ 8/10
$215.44 $209.23▼ −2.88%▼ −2.76%$206.54 (−4.13%)
Aug 26, 2026
5w ago
Press Release
BULLISH ★ 8/10
$215.44 $209.23▼ −2.88%▼ −2.76%$206.54 (−4.13%)
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 3/10
$211.38 $209.87▼ −0.71%▼ −0.18%$206.54 (−2.29%)
Jul 2, 2026
13w ago
Press Release
BULLISH ★ 7/10
$189.24 $191.13▲ +1.00%▲ +0.07%$206.54 (+9.14%)
Jul 1, 2026
13w ago
Insider Cluster
NEUTRAL ★ 2/10
$187.51 $190.46▲ +1.57%▲ +1.31%$206.54 (+10.15%)
Jun 22, 2026
14w ago
8-K
NEUTRAL ★ 2/10
$165.81 $192.62▲ +16.17%▲ +16.62%$206.54 (+24.56%)
Showing 10 of 26

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