ANALYST-DOWNGRADE

REGN

REGENERON PHARMACEUTICALS, INC.
BEARISH
Impact 2/10
Processed4mo ago SECanalyst-REGN-citigrou-20260518
2 firms acted on REGN: Citigroup, Leerink Partners
Actionable Insight ▼ Bearish

The downgrades from low-accuracy firms, while cautionary, are not statistically strong. Given consensus bullishness and improving EPS revisions, traders could view weakness toward $700 as a potential buying entry, but should wait for price stability or confirmation from a high-accuracy firm before committing.

DirectionBearish
Final — all horizons settled through T+60d
REGN ▲ +26.80% at T+60d
SHORT call ✗ call lost -26.80% · α vs SPY -22.22% · entry $629.34 → $797.99
Entry anchored
May 18, 11:01 AM ET
via exchange tick
T+1d
+0.07%
call -0.07% · α -0.72%
$629.76
settled 5mo ago
T+5d
+0.45%
call -0.45% · α +1.17%
$632.17
settled 4mo ago
T+20d
-2.28%
call +2.28% · α +4.47%
$614.98
settled 4mo ago
T+60d
+26.80%
call -26.80% · α -22.22%
$797.99
settled 7w ago

Price Chart

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Executive Summary

On May 18, 2026, two firms downgraded Regeneron Pharmaceuticals (REGN). Citigroup cut from Buy to Neutral, slashed price target from $900 to $700, nearly in line with the current $698.25. Leerink Partners downgraded from Outperform to Market Perform with a $641 target, implying ~8% downside. Both firms have below-average track records on REGN (Citi 43% accuracy on 7 calls, Leerink 50% on 2 calls). Consensus remains strongly bullish: 30 of 38 analysts (79%) rate Buy or Strong Buy, with a mean price target of $875.31 (25.4% upside). EPS revision momentum is positive, with 15 upgrades vs 6 downgrades for the next quarter. Insider sales are small and routine; institutional activity is mixed (Two Sigma trimming but Norges Bank adding a $1B position). While the cluster downgrade signals near-term caution, the positive consensus and earnings momentum suggest the stock may find support near $700. The low accuracy of the downgrading firms reduces the significance of this action.

Impact Score

Base Score
2/7
LLM Adjustment
+0
Final Score
2/10

Consensus & Targets

Buy / Strong Buy
30 (79%)
Hold
8
Sell / Strong Sell
0
Total Analysts
28
Mean PT
$875.31
Median PT
$882.50
High PT
$1,057.00
Low PT
$730.00
Current Price
$698.25
Implied Upside
+25.4%

Consensus is heavily bullish: 30 of 38 analysts (79%) rate Buy or Strong Buy, 8 Hold (21%), and 0 Sell. The average price target is $875.31 with a median of $882.5. The downgrades are contrarian to the consensus view, which sees 25.4% upside from current levels.

Mean price target $875.31, median $882.5, high $1057, low $730. Current price $698.25 implies 25.4% upside to mean. Citigroup's new $700 PT of $700 is below the consensus low of $730, and Leerink's $641 is even lower. Both new targets are well below the consensus mean of $875.31, reflecting a more pessimistic view than the average analyst.

Recent Analyst Activity

DateFirmActionRatingPrice Target
2026-05-18JP MorganmaintainOverweight$850.00
2026-05-18Piper SandlermaintainOverweight$855.00
2026-05-18Wells FargomaintainEqual-Weight$700.00
2026-05-18RBC CapitalmaintainSector Perform$707.00
2026-05-18CitigroupdowngradeNeutral$700.00
2026-05-18Leerink PartnersdowngradeMarket Perform$641.00
2026-05-01GuggenheimmaintainBuy$995.00
2026-04-30RBC CapitalmaintainSector Perform$762.00
2026-04-30BarclaysmaintainOverweight$917.00
2026-04-30Truist SecuritiesmaintainBuy$796.00

In the last 30 days, REGN has seen 0 upgrades and 2 downgrades (these). EPS revisions for the current quarter are positive: 15 upward vs 6 downward in 30 days, with consensus rising $12.30 to $13.09. Full-year EPS also revised up 16 vs 7 down. This positive earnings momentum contrasts with the negative analyst action.

Firm Track Record — Citigroup

Citigroup accuracy: 55% on 4355 calls | avg return: 4.9%

Industry benchmark: mean 51% ± 11%. Top tier: ≥61% (mean + 1σ). Based on 15 firms with ≥5 scored calls.

FirmAccuracyCallsAvg Returnvs Average
UBS67%4/65.1%top tier
Canaccord Genuity57%4/79.4%above average
TD Cowen50%1/23.1%below average
Bernstein50%1/26.2%below average
Cantor Fitzgerald50%4/8-4.5%below average
BMO Capital50%3/6-3.7%below average
Morgan Stanley50%5/104.1%below average
Goldman Sachs50%1/2-3.6%below average
Leerink Partners50%1/2-23.7%below average
Evercore ISI Group50%1/2-4.9%below average

Citigroup has a 43% accuracy rate on 7 REGN calls, with an average return of 3.8% — below the average. Leerink is 50% on 2 calls with a -23.7% average return, the worst among all firms. The best performer is UBS (67% accuracy on 6 calls, +5.1% return); the worst by accuracy is RBC Capital (33% on 18 calls, -8.9%). Both downgrading firms are among the lowest in accuracy on this name.

Earnings Estimates

Next earnings: Jul 30, 2026

PeriodEPS Est.EPS RangeRevenueRevisions (7d)
0q$10.86$8.27 — $13.25$3.8B↑2 ↓0
+1y$48.20$41.10 — $60.05$17.6B↑2 ↓0
+1q$13.09$9.36 — $17.10$4.2B↑5 ↓0
0y$46.50$38.82 — $53.61$15.9B↑6 ↓0

Cross-Platform Signals

Insider Trades (90d)
0 buys / 4 sells
Congressional
Ro Khanna (democrat) — buy $1,001 - $15,000
Institutional
TWO SIGMA INVESTMENTS, LP — trim (-40.2%)
Institutional
RENAISSANCE TECHNOLOGIES LLC — near_exit (-96.7%)
Institutional
SOUND SHORE MANAGEMENT INC /CT/ — add (52.9%)

Insider sales are small ($10k by CFO Ryan in April/May, $38k by director Zoghbi in February) and likely routine; no informative cluster. Congressional: Rep. Khanna bought $1k‑$15k in April — negligible. Institutional actions are mixed: Two Sigma trimmed 40% and Renaissance near-exited (‑97%), but Norges Bank initiated a $1B market position and Sound Shore added 53%. Short interest is not available. Overall, the downgrade divergence with still‑positive institutional buying and upward EPS revisions, reducing the joint signal reliability of the bearish signal.

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

Report based on filing metadata.

26 reports for REGN
Performance horizon
83% Hit rate 10 of 12 directional calls best @ T+60▲ +26.47%May 21, 2026
Filters
Rows
Reports for REGN — sortable, filterable
TypeNow
Oct 1, 2026
1d ago
ANALYST-UPGRADE
BULLISH ★ 4/10
—awaiting T+20——
Sep 3, 2026
29d ago
Insider Cluster
NEUTRAL ★ 2/10
$843.47 $735.20▼ −12.84%▼ −11.65%$735.20 (−12.84%)
Aug 24, 2026
5w ago
Court Ruling
BULLISH ★ 5/10
$828.50 $803.90▼ −2.97%▼ −4.28%$735.20 (−11.26%)
Aug 20, 2026
6w ago
Press Release
NEUTRAL ★ 5/10
$826.64 $784.85▼ −5.06%▼ −5.06%$735.20 (−11.06%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$797.99 $793.26▼ −0.59%▲ +1.30%$735.20 (−7.87%)
Aug 11, 2026
7w ago
Court Ruling
BULLISH ★ 5/10
$797.00 $807.65▲ +1.34%▲ +2.40%$735.20 (−7.75%)
Jul 30, 2026
9w ago
8-K
BULLISH ★ 7/10
$738.34 $807.71▲ +9.40%▲ +5.43%$735.20 (−0.43%)
Jul 30, 2026
9w ago
Press Release
BULLISH ★ 7/10
$738.34 $807.71▲ +9.40%▲ +5.43%$735.20 (−0.43%)
Jul 27, 2026
9w ago
Press Release
BEARISH ★ 6/10
$695.18 $833.56▼ −19.91%▼ −16.52%$735.20 (−5.76%)
Jul 17, 2026
11w ago
Press Release
NEUTRAL ★ 3/10
$676.69 $800.70▲ +18.33%▲ +13.88%$735.20 (+8.65%)
Showing 10 of 26

US Market Status

Market Closed — Opens Mon (64h 12m)

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Report published May 18, 2026