SecBot SecBot
PRESS-RELEASE ·Filed Aug 11, 2026

PRLD

Prelude Therapeutics, Incorporated
BULLISH
Impact 5/10
Horizonmonths Processed2mo ago WireGlobeNewswire
Press release · Earnings
Actionable Insight ▲ Bullish

The beat is driven by cost cuts and a new revenue line, not pipeline progress. Watch for Phase 1 data readouts on PRT13722 and PRT12396 as the next catalysts; the cash runway into 2028 provides a long development horizon.

DirectionBullish
Confidencehigh
Horizonmonths
Latest settled — T+20d ⚠ clustered
PRLD ▼ -4.32% at T+20d
LONG call ✗ call lost -4.32% · α vs SPY -3.26% · entry $5.32 → $5.09
Next anchor: T+60d in 8d
Latest observation: T+52 -28.02% FF3 residual α
Entry = T+0 close
Aug 11, 2026
via day close
T+1d
+7.71%
call +7.71% · α +7.46%
$5.73
settled 3mo ago
T+5d
+8.08%
call +8.08% · α +8.49%
$5.75
settled 2mo ago
T+20d
-4.32%
call -4.32% · α -3.26%
$5.09
settled 7w ago
T+60d
Pending
in 8d

Price Chart

Loading chart...

Executive Summary

Prelude Therapeutics reported Q2 2026 EPS of -$0.14, beating consensus of -$0.18 by 22.2%, and generated $5.7M in revenue (vs $0 consensus). Net loss narrowed to $13.9M from $31.2M a year ago, with cash runway into Q2 2028. The beat is driven by cost controls and a new revenue stream, but the company remains pre-revenue on its pipeline, limiting the stock-moving impact.

Key Financial Metrics

EPS
−$0.14
est −$0.18 · +22.2%
Revenue
$5.7M
est $0.00
Rating
beat

Key Facts

  • Q2 2026 EPS -$0.14 beat consensus -$0.18 (22.2% beat)
  • Revenue of $5.7M vs $0 consensus and $0 year-ago
  • Net loss narrowed to $13.9M from $31.2M YoY
  • Cash, equivalents, restricted cash, and marketable securities $155.2M as of June 30, 2026
  • Cash runway expected into Q2 2028
  • R&D expenses fell to $16.1M from $25.8M YoY; G&A fell to $5.0M from $6.4M
  • Phase 1 study of PRT13722 (KAT6A degrader) expected to initiate in Q4 2026
  • Enrollment continues in Phase 1 of PRT12396 (JAK2V617F inhibitor) for PV and MF

Financial Impact

EPS beat of $0.04 vs consensus; revenue surprise of $5.7M; net loss improvement of $17.3M YoY

epsrevenuenet losscash runway

Risk Factors

  • Pre-revenue pipeline with no approved products; clinical trial risks for PRT13722 and PRT12396
  • Revenue of $5.7M may be one-time or non-recurring; sustainability unclear

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
89% bullish (9 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3342538
13 reports for PRLD
Performance horizon
63% Hit rate @ T+1 5 of 8 directional calls Went positive at some point 6 of 8 best @ T+1▲ +22.48%Apr 21, 2026
Filters
Rows
Reports for PRLD — sortable, filterable
TypeNow
Sep 22, 2026
4w ago
Institutional Cluster
BULLISH ★ 4/10
$4.85 $4.31▼ −11.13%▼ −10.41%$3.69 (−23.81%)
Sep 10, 2026
6w ago
8-K
BULLISH ★ 6/10
$4.67 $4.59▼ −1.71%▼ −2.57%$3.69 (−20.88%)
Sep 10, 2026
6w ago
Press Release
NEUTRAL ★ 4/10
$4.67 $4.59▼ −1.71%▼ −2.57%$3.69 (−20.88%)
Aug 11, 2026
11w ago
8-K
NEUTRAL ★ 4/10
$5.32 $5.73▲ +7.71%▲ +7.46%$3.69 (−30.55%)
Aug 11, 2026
11w ago
Press Release
BULLISH ★ 5/10
$5.32 $5.73▲ +7.71%▲ +7.46%$3.69 (−30.55%)
May 12, 2026
24w ago
8-K
BULLISH ★ 6/10
$4.64 $4.66▲ +0.43%▼ −0.14%$3.69 (−20.37%)
May 12, 2026
24w ago
Press Release
BULLISH ★ 7/10
$4.64 $4.66▲ +0.43%▼ −0.14%$3.69 (−20.37%)
Apr 28, 2026
25w ago
3
BULLISH ★ 6/10
$4.27 $4.27· 0.00%▼ −1.02%$3.69 (−13.47%)
Apr 21, 2026
27w ago
Insider Cluster
BULLISH ★ 8/10
$4.27 $5.23▲ +22.48%▲ +21.46%$3.69 (−13.47%)
Apr 20, 2026
27w ago
8-K
BULLISH ★ 7/10
$4.51 $4.62▲ +2.44%▲ +3.09%$3.69 (−18.07%)
Showing 10 of 13

US Market Status

Market Open — Closes in 6h 18m

Subscribe to SecBot

Get Real-Time SEC Filing Intelligence

Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.

Create a free account Live analysis, Telegram alerts, watchlists and the MCP server for subscribers
Report published Aug 11, 2026