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Institutional Cluster ·Filed Sep 22, 2026

PRLD

Prelude Therapeutics Inc
BULLISH
Impact 4/10
Horizonweeks Processed1mo ago
Institutional cluster: 14 buyers, 5 sellers (bullish)
Actionable Insight ▲ Bullish

The cluster is overwhelmingly passive/index-driven, not thesis-driven. Monitor upcoming 13F filings for Q3 to see if these positions were held or reversed. Without insider buying or an active-fund catalyst, the signal is weak for a standalone trade.

DirectionBullish
Confidencemedium
Horizonweeks
Latest settled — T+20d
PRLD ▼ -27.22% at T+20d
LONG call ✗ call lost -27.22% · α vs SPY -26.66% · entry $4.85 → $3.53
Next anchor: T+60d in 7w
Latest observation: T+23 -27.94% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
-11.13%
call -11.13% · α -10.41%
$4.31
settled 5w ago
T+5d
-18.35%
call -18.35% · α -17.16%
$3.96
settled 28d ago
T+20d
-27.22%
call -27.22% · α -26.66%
$3.53
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

A strong institutional accumulation cluster emerged in PRLD during Q2 2026, with 14 buyers adding $27.0M in net new holdings (total $36.7M) versus only 5 sellers trimming $747K. The buying is dominated by mega-passive funds (Vanguard, BlackRock, Geode, Northern Trust, UBS, Morgan Stanley) and one quant fund (Millennium), suggesting broad index-driven or systematic rebalancing rather than a concentrated active thesis. The net direction is heavily bullish by dollar volume, but the passive composition and small absolute dollar base ($36.7M total) limit the signal's conviction.

Key Financial Metrics

Direction
accumulating
Buy Value
$36.7M
Sell Value
$747.0K
Net Flow
$27.0M

Institutional Positions

Net institutional flow: $27.0M

▲ Buyers (14)

InstitutionActionChangePosition ValueValue Δ
BlackRockDOUBLED+458.4%$9.6M$8.5M
VanguardADD+65.3%$12.2M$7.5M
GeodeDOUBLED+178.3%$4.5M$3.5M
MillenniumDOUBLED+120.8%$4.5M$3.2M
Morgan StanleyADD+56.4%$2.7M$1.6M

▼ Sellers (5)

InstitutionActionChangePrev ValueValue Δ
CitadelNEAR_EXIT-81.9%$425.0K-$305.0K
Marshall WaceTRIM-46.9%$1.2M-$211.0K
Goldman SachsTRIM-48.9%$809.0K-$165.0K

Key Facts

  • 14 institutional buyers added $27.0M in net new PRLD positions during Q2 2026, bringing total buyer holdings to $36.7M
  • 5 sellers reduced holdings by $747K, a negligible amount relative to buying
  • Top buyers by dollar increase: BlackRock (+$8.5M), Vanguard (+$7.5M), Geode (+$3.5M), Millennium (+$3.2M), Morgan Stanley (+$1.6M)
  • Mega-passive funds (Vanguard, BlackRock, Geode, Northern Trust, UBS, Morgan Stanley, JPMorgan) account for the vast majority of buying volume
  • Only one active quant fund (Millennium) appears among buyers; no activist or event-driven funds are present
  • Sellers include Citadel (near-exit, -$305K), Marshall Wace (trim, -$211K), and Goldman Sachs (trim, -$165K)

Financial Impact

14 institutions accumulated $27.0M in net new PRLD positions during Q2 2026, while 5 sellers reduced holdings by $747K. Total institutional buyer holdings reached $36.7M.

institutional ownershipfloat demand

Risk Factors

  • 13F data is 45 days stale; positions may have already been unwound in Q3
  • Passive/index fund buying may reflect index rebalancing, not fundamental conviction
  • No activist or event-driven funds present; no insider buying confluence
  • Small absolute dollar base ($36.7M) limits market impact

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-PRLD-2026-Q2
13 reports for PRLD
Performance horizon
75% Hit rate @ T+1 6 of 8 directional calls Went positive at some point 7 of 8 best @ T+1▲ +22.48%Apr 21, 2026
Filters
Rows
Reports for PRLD — sortable, filterable
TypeNow
Sep 22, 2026
4w ago
Institutional Cluster
BULLISH ★ 4/10
$4.85 $4.31▼ −11.13%▼ −10.41%—
Sep 10, 2026
6w ago
8-K
BULLISH ★ 6/10
$4.67 $4.59▼ −1.71%▼ −2.57%—
Sep 10, 2026
6w ago
Press Release
NEUTRAL ★ 4/10
$4.67 $4.59▼ −1.71%▼ −2.57%—
Aug 11, 2026
10w ago
8-K
NEUTRAL ★ 4/10
$5.32 $5.73▲ +7.71%▲ +7.46%—
Aug 11, 2026
10w ago
Press Release
BULLISH ★ 5/10
$5.32 $5.73▲ +7.71%▲ +7.46%—
May 12, 2026
23w ago
8-K
BULLISH ★ 6/10
$4.64 $4.66▲ +0.43%▼ −0.14%—
May 12, 2026
23w ago
Press Release
BULLISH ★ 7/10
$4.64 $4.66▲ +0.43%▼ −0.14%—
Apr 28, 2026
25w ago
3
BULLISH ★ 6/10
$4.27 $4.27· 0.00%▼ −1.02%—
Apr 21, 2026
27w ago
Insider Cluster
BULLISH ★ 8/10
$4.27 $5.23▲ +22.48%▲ +21.46%—
Apr 20, 2026
27w ago
8-K
BULLISH ★ 7/10
$4.51 $4.62▲ +2.44%▲ +3.09%—
Showing 10 of 13

US Market Status

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Report published Sep 22, 2026