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Insider Cluster (3 insiders) ·Filed Apr 21, 2026

PRLD

Prelude Therapeutics Inc
BULLISH
Impact 8/10
Horizonweeks Processed6mo ago
Insider cluster: 3 insiders, $15.5M total
Actionable Insight ▲ Bullish

The significant insider buying suggests confidence in upcoming catalysts. Monitor for news on clinical trials or partnerships that may have prompted this accumulation.

DirectionBullish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
PRLD ▼ -10.30% at T+60d
LONG call ✗ call lost -10.30% · α vs SPY -14.42% · entry $4.27 → $3.83
Entry = T+0 close
Apr 28, 2026
via day close
T+1d
+22.48%
call +22.48% · α +21.46%
$5.23
settled 6mo ago
T+5d
+13.35%
call +13.35% · α +10.24%
$4.84
settled 6mo ago
T+20d
-7.96%
call -7.96% · α -14.01%
$3.93
settled 5mo ago
T+60d
-10.30%
call -10.30% · α -14.42%
$3.83
settled 3mo ago

Price Chart

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Executive Summary

Three major insiders (OrbiMed Advisors, Baker Bros. Advisors, and David P. Bonita) purchased a combined $15.51M of PRLD shares at $4.44, representing ~5.4% of market cap. This is a strong vote of confidence from sophisticated healthcare investors.

Key Financial Metrics

Direction
buying
Total Value
$15.5M
Insiders
3

Key Facts

  • Three director/10% owners purchased $15.51M of PRLD shares at $4.44
  • Purchases represent ~5.4% of market cap
  • Buyers include OrbiMed Advisors, Baker Bros. Advisors, and David P. Bonita

Financial Impact

$15.51M of insider purchases at $4.44 per share, ~5.4% of market cap

stock pricemarket sentiment

Risk Factors

  • Biotech drug development risk

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
89% bullish (9 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-PRLD-1777410925822
13 reports for PRLD
Performance horizon
63% Hit rate @ T+1 5 of 8 directional calls Went positive at some point 6 of 8 best @ T+5▲ +9.37%Apr 28, 2026
Filters
Rows
Reports for PRLD — sortable, filterable
TypeNow
Sep 22, 2026
5w ago
Institutional Cluster
BULLISH ★ 4/10
$4.85 $4.31▼ −11.13%▼ −10.41%$3.88 (−20.00%)
Sep 10, 2026
6w ago
8-K
BULLISH ★ 6/10
$4.67 $4.59▼ −1.71%▼ −2.57%$3.88 (−16.92%)
Sep 10, 2026
6w ago
Press Release
NEUTRAL ★ 4/10
$4.67 $4.59▼ −1.71%▼ −2.57%$3.88 (−16.92%)
Aug 11, 2026
11w ago
8-K
NEUTRAL ★ 4/10
$5.32 $5.73▲ +7.71%▲ +7.46%$3.88 (−27.07%)
Aug 11, 2026
11w ago
Press Release
BULLISH ★ 5/10
$5.32 $5.73▲ +7.71%▲ +7.46%$3.88 (−27.07%)
May 12, 2026
24w ago
8-K
BULLISH ★ 6/10
$4.64 $4.66▲ +0.43%▼ −0.14%$3.88 (−16.38%)
May 12, 2026
24w ago
Press Release
BULLISH ★ 7/10
$4.64 $4.66▲ +0.43%▼ −0.14%$3.88 (−16.38%)
Apr 28, 2026
26w ago
3
BULLISH ★ 6/10
$4.27 $4.27· 0.00%▼ −1.02%$3.88 (−9.13%)
Apr 21, 2026
27w ago
Insider Cluster
BULLISH ★ 8/10
$4.27 $5.23▲ +22.48%▲ +21.46%$3.88 (−9.13%)
Apr 20, 2026
27w ago
8-K
BULLISH ★ 7/10
$4.51 $4.62▲ +2.44%▲ +3.09%$3.88 (−13.97%)
Showing 10 of 13

US Market Status

Market Closed — Opens Thu (11h 37m)

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Report published Apr 28, 2026